Understanding mosquito smell system: a new frontier in mosquito control. This project aims to identify and functionally investigate mosquito smell receptors, which are critical in detecting volatile compounds and locating their hosts from a considerable distance away. Mosquitoes display preferences for certain hosts over others, primarily determined by volatile chemicals produced by hosts. This study builds on recently discovered, novel, host-derived volatile compounds, which can elicit robust r ....Understanding mosquito smell system: a new frontier in mosquito control. This project aims to identify and functionally investigate mosquito smell receptors, which are critical in detecting volatile compounds and locating their hosts from a considerable distance away. Mosquitoes display preferences for certain hosts over others, primarily determined by volatile chemicals produced by hosts. This study builds on recently discovered, novel, host-derived volatile compounds, which can elicit robust responses and attractiveness from mosquitoes. Expected outcomes of the project are enhanced understanding of mosquito smell system and behaviours. This could provide significant benefits to how we can fight mosquitoes and mosquito-transmitted diseases in a more efficient and environmentally responsible way.Read moreRead less
TELEPHONE COUNSELLING FOR MAINTENANCE OF PHYSICAL ACTIVITY, WEIGHT LOSS And GLYCAEMIC CONTROL IN TYPE 2 DIABETES
Funder
National Health and Medical Research Council
Funding Amount
$1,285,894.00
Summary
Regular exercise, a healthy diet and weight loss are key to managing type 2 diabetes, yet these are major challenges for most people with diabetes. This study will evaluate the impact of a telephone counselling program to assist people with type 2 diabetes to exercise, eat a healthy diet and lose weight, with the goal of helping them to sustain these changes over the long-term. It is expected that these lifestyle changes will also result in improved blood glucose control and quality of life.
Early evolutionary origins of mechanosensory transduction: structure, function and phylogenetic studies of the family of mechanosensitive channels in cell-walled organisms. The proposed project is based on the recent progress the applicants have made by (i) identifying a novel family of mechanosensitive (MS) channels in cell-walled organisms, which include Archaea and Bacteria (prokaryotes), as well as fungi and plants (eukaryotes), and (ii) determining basic aspects of the structural dynamics ....Early evolutionary origins of mechanosensory transduction: structure, function and phylogenetic studies of the family of mechanosensitive channels in cell-walled organisms. The proposed project is based on the recent progress the applicants have made by (i) identifying a novel family of mechanosensitive (MS) channels in cell-walled organisms, which include Archaea and Bacteria (prokaryotes), as well as fungi and plants (eukaryotes), and (ii) determining basic aspects of the structural dynamics of MscL, the prototype MS channel, using electronparamagnetic resonance spectroscopy and molecular dynamics simulations in combination with the patch clamp technique. The aim of the project is to elucidate the molecular principles underlying the function of MS channels, which is of fundamental importance for understanding of the biophysics and physiology of mechanosensory transduction throughout the biological world.Read moreRead less
Force from lipids: the role of the lipid bilayer in mechanosensory transduction. The proposed research will significantly contribute to a better understanding of the wide range of physiological processes underlying mechanosensory transduction in living cells. The direct benefit for Australian science consists of: (i) strengthening international links with leading overseas laboratories, and (ii) accessing the state-of-the-art expertise not available in Australia. The acquired knowledge will aid i ....Force from lipids: the role of the lipid bilayer in mechanosensory transduction. The proposed research will significantly contribute to a better understanding of the wide range of physiological processes underlying mechanosensory transduction in living cells. The direct benefit for Australian science consists of: (i) strengthening international links with leading overseas laboratories, and (ii) accessing the state-of-the-art expertise not available in Australia. The acquired knowledge will aid in developing and designing artificial tactile sensors inspired by their biological models studied in this project. Long-term, the project is expected to make an original contribution towards developing new technologies and novel medical applications, both of which promise to be of great national benefit.Read moreRead less
Revealing the beneficial effects of acoustic stimulation on the human brain. This project aims to provide greater understanding of the neural mechanisms by which initiation of motor responses can be improved by unexpected auditory stimulation. Initiating motor actions appears natural and effortless, but is underpinned by complex neural mechanisms that are not well understood. Using novel brain stimulation techniques, the project aims to assess the potential for properly timed strong sensory stim ....Revealing the beneficial effects of acoustic stimulation on the human brain. This project aims to provide greater understanding of the neural mechanisms by which initiation of motor responses can be improved by unexpected auditory stimulation. Initiating motor actions appears natural and effortless, but is underpinned by complex neural mechanisms that are not well understood. Using novel brain stimulation techniques, the project aims to assess the potential for properly timed strong sensory stimulation during movement preparation to induce neural plasticity and motor learning. This knowledge would have important implications across a number of fields, including neuroscience, sports science, and applied ergonomics.Read moreRead less
ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the d ....ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the design of peptides and proteins for targeted scientific, agricultural, biotechnology, animal health and pharmaceutical applications. CIPPS will assemble leading researchers from diverse disciplines to create a sustainable national entity that will drive new Australian industries and train next generation researchers.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC150100019
Funder
Australian Research Council
Funding Amount
$4,571,797.00
Summary
ARC Training Centre for Liquefied Natural Gas Futures. ARC Training Centre for Liquefied Natural Gas Futures. This training centre aims to deliver projects and training to enable future Australian Liquefied Natural Gas (LNG) production from reserves in deep water, at small or remote on-shore locations, with greater efficiency, less environmental impact, and at lower cost than currently possible. This should be accomplished via research projects undertaken by the PhD students and research fellows ....ARC Training Centre for Liquefied Natural Gas Futures. ARC Training Centre for Liquefied Natural Gas Futures. This training centre aims to deliver projects and training to enable future Australian Liquefied Natural Gas (LNG) production from reserves in deep water, at small or remote on-shore locations, with greater efficiency, less environmental impact, and at lower cost than currently possible. This should be accomplished via research projects undertaken by the PhD students and research fellows with guidance from the centre’s industrial partners. The centre’s expected legacy is a unique research and training facility, designed for future integration into a microscale LNG plant. The anticipated research and training outcomes will help to ensure Australia plays a leading role in future global LNG developments.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100184
Funder
Australian Research Council
Funding Amount
$183,437.00
Summary
Femtoliter Liquid Deposition Facility. This project aims to create a research capacity for direct printing of femtolitre volumes of functional liquids onto devices and surfaces. This project expects to enable the development of new sensing and electronic devices that require a novel fabrication step with delicate materials that cannot be deposited using existing processes. Expected outcomes include new chemical and biological sensors created through collaborative research between the partner in ....Femtoliter Liquid Deposition Facility. This project aims to create a research capacity for direct printing of femtolitre volumes of functional liquids onto devices and surfaces. This project expects to enable the development of new sensing and electronic devices that require a novel fabrication step with delicate materials that cannot be deposited using existing processes. Expected outcomes include new chemical and biological sensors created through collaborative research between the partner institutions and researchers. The benefits of this project should include the creation of a new rapid prototyping facility for Australian researchers, and the application of these capabilities for the development of new low-cost sensors for environmental gas sensing and glucose monitoring.Read moreRead less
Special Research Initiatives - Grant ID: SR0354636
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecula ....Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecular scale computations in the fields of nanoscience, biomaterials, biotechnology, biomedical science and environmental science. It will uncover and explore critical new interdisciplinary science and create new molecular-based paradigms that will drive advances in these fields over the next decade.Read moreRead less
Improving Sexual Health In Men With Prostate Cancer: Randomised Controlled Trial Of Exercise And Psychosexual Therapies
Funder
National Health and Medical Research Council
Funding Amount
$583,416.00
Summary
Sexual dysfunction is one of the most common and distressing side effects of prostate cancer. Despite being a critical survivorship care issue, there is a clear gap in knowledge surrounding the optimal treatment of sexual dysfunction in men with prostate cancer. This project examines whether exercise aids in the management of sexual dysfunction and explores if an integrated treatment model incorporating pharmacological, exercise and psychosexual therapies maximises improvement in sexual health.