Discovery Early Career Researcher Award - Grant ID: DE180100741
Funder
Australian Research Council
Funding Amount
$342,996.00
Summary
Harnessing neural plasticity with brain stimulation. This project aims to investigate the links between the molecular mechanisms underlying brain plasticity and the effects of non-invasive brain stimulation. It will use a novel approach that integrates genetics, electrophysiology and biological modelling. Plasticity underpins all learning, memory and aging. Brain stimulation can drive plasticity in humans, but these effects are extremely difficult to harness and vary widely between people. Expec ....Harnessing neural plasticity with brain stimulation. This project aims to investigate the links between the molecular mechanisms underlying brain plasticity and the effects of non-invasive brain stimulation. It will use a novel approach that integrates genetics, electrophysiology and biological modelling. Plasticity underpins all learning, memory and aging. Brain stimulation can drive plasticity in humans, but these effects are extremely difficult to harness and vary widely between people. Expected outcomes include a critical understanding of the fundamental mechanisms governing plasticity. This will provide significant benefits such as the development of individually optimised brain stimulation protocols, enabling tailored, reliable approaches to address brain function and cognition.Read moreRead less
The Australian naturalistic driving study: innovation in road safety research and policy. A revolutionary new approach, the naturalistic driving study, will investigate what people actually do when they drive, in normal and safety-critical situations. It will provide Australia with answers to some intractable, high priority, road safety problems that cannot be answered using current methods, thereby saving hundreds of lives.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100050
Funder
Australian Research Council
Funding Amount
$570,000.00
Summary
Integrated facility for recording driver and road user behaviour. The integrated facility will be used to record and analyse data on driver and road user behaviour, in normal and safety-critical situations, for thousands of Australian drivers. The data yielded will be used to develop new and improved countermeasures for reducing road deaths and serious injuries on Australian roads.
Strengthening community partnerships to promote adolescent school engagement and prevent problems such as alcohol misuse and violence. The project will reduce community rates of adolescent school non-attendance, adolescent alcohol misuse and antisocial behaviour. Adolescent school exclusion, alcohol use and antisocial behaviour are highly prevalent in Australia, and can be reduced using a variety of strategies that are coordinated at the school and community level. The project will decrease adol ....Strengthening community partnerships to promote adolescent school engagement and prevent problems such as alcohol misuse and violence. The project will reduce community rates of adolescent school non-attendance, adolescent alcohol misuse and antisocial behaviour. Adolescent school exclusion, alcohol use and antisocial behaviour are highly prevalent in Australia, and can be reduced using a variety of strategies that are coordinated at the school and community level. The project will decrease adolescent problems through community improvements in child and adolescent protective influences and reductions in risk influences. Furthermore, the project will equip communities with the capacity to learn how to identify and implement strategies to address the major influences that have the potential to reduce adolescent behaviour problems.Read moreRead less
Common synaptic inputs to human upper airway muscles. Changes in the activity of upper airway muscles at sleep onset contribute to the development of Obstructive Sleep Apnoea. The aim of this project is to investigate how the brain controls upper airway muscles during wakefulness and sleep and to identify the pathological processes that lead to the development of Obstructive Sleep Apnoea.
How inhibition shapes human brain oscillations and working memory capacity. This project aims to investigate the link between inhibitory mechanisms, gamma oscillations and working memory in humans. Retaining information in short-term ‘working’ memory is crucial for cognition, influencing our personality and intelligence. However, the brain mechanisms underlying this process are unclear. Evidence from animal/computational research indicates that brain oscillations in high frequency ‘gamma’ bands, ....How inhibition shapes human brain oscillations and working memory capacity. This project aims to investigate the link between inhibitory mechanisms, gamma oscillations and working memory in humans. Retaining information in short-term ‘working’ memory is crucial for cognition, influencing our personality and intelligence. However, the brain mechanisms underlying this process are unclear. Evidence from animal/computational research indicates that brain oscillations in high frequency ‘gamma’ bands, which depend on neural inhibition, are critical for working memory. Mapping a path from molecules to cognition will detail how neural mechanisms shape human behavioural performance and guide efforts to enhance memory and cognitive function.Read moreRead less
Left of centre: Attentional distortions in the mental representation of space in healthy and clinical populations. Stroke patients cost the Australian economy $1.3bn pa in addition to their social burden, but effective diagnosis and rehabilitation is impeded by a lack of fundamental research into the cognitive and neural mechanisms that underlie attentional disorders. Our research will provide significant new insights into how the brain deploys attention in external and imagined space and will l ....Left of centre: Attentional distortions in the mental representation of space in healthy and clinical populations. Stroke patients cost the Australian economy $1.3bn pa in addition to their social burden, but effective diagnosis and rehabilitation is impeded by a lack of fundamental research into the cognitive and neural mechanisms that underlie attentional disorders. Our research will provide significant new insights into how the brain deploys attention in external and imagined space and will lead to more effective management and treatment of stroke victims. Our new test of attentional disorders is independent of a patient's inability to see or move and will enable more effective diagnosis. Our research provides the fundamental knowledge base for our discipline and is vital for developing the next generation of Australia's cognitive neuroscientists. Read moreRead less
Functional impact of high fat and high sugar diets on memory encoding. This project aims to determine the functional mechanisms of how fats and sugar affect neuronal processes vital for learning and memory. Expected outcomes will define the neural mechanisms underpinning cognitive changes in emotional and spatial memory encoding, and how these relate to brain and metabolic parameters. This will provide benefits by unveiling the possible consequences of dietary fat and sugar on the brain, and th ....Functional impact of high fat and high sugar diets on memory encoding. This project aims to determine the functional mechanisms of how fats and sugar affect neuronal processes vital for learning and memory. Expected outcomes will define the neural mechanisms underpinning cognitive changes in emotional and spatial memory encoding, and how these relate to brain and metabolic parameters. This will provide benefits by unveiling the possible consequences of dietary fat and sugar on the brain, and the mechanisms of neuroplasticity enhancing interventions.Read moreRead less
Killing which averts suffering: the role of norms and empathy. Abattoir workers and butchers kill animals to prepare food, farmers to cull stock, and veterinarians to alleviate suffering. Soldiers kill other humans in war, police or security guards to protect the public, and doctors to enact legal euthanasia. Research shows that these tasks can be confronting, and even traumatic. This project aims to test the processes through which people learn socially supported palliative killing to avert suf ....Killing which averts suffering: the role of norms and empathy. Abattoir workers and butchers kill animals to prepare food, farmers to cull stock, and veterinarians to alleviate suffering. Soldiers kill other humans in war, police or security guards to protect the public, and doctors to enact legal euthanasia. Research shows that these tasks can be confronting, and even traumatic. This project aims to test the processes through which people learn socially supported palliative killing to avert suffering and their neural underpinnings, with a focus on norms and empathic distress. It will focus on two core samples: veterinarians, who must euthanize animals, and health practitioners in Victoria, where legal changes will introduce ‘voluntary assisted dying’ in mid-2019. It will investigate how practitioners learn palliative killing, and what the impact is on psychological variables such as empathy and identity. It will generate new understandings of social influence around life and death decisions, provide an evidence basis to inform policy makers, and help institutions and practitioners seeking to manage distress and respond to fast-moving, controversial policy changes.Read moreRead less
Left to right is front to back: attentional distortions in near and far space for healthy and clinical populations. We are investigating a perceptual bias that makes people think objects right in front of them are actually slightly to the right but objects far away are slightly to the left. This project will help understand why this happens, to help reduce traffic collisions and help people with brain damage that causes similar perceptual biases.