Discovery Early Career Researcher Award - Grant ID: DE180100202
Funder
Australian Research Council
Funding Amount
$365,058.00
Summary
Interplay between plasticity and senescence. This project aims at bridging two fundamental human stressors together in a quantitative genetic framework. The environment changes globally on a huge scale coupled with effect on the age-structures and genetic composition of countless populations by over-harvesting and exploitation. This project will provide significant benefits, such as potential strategies of dealing with future human-induced changes more effectively.
Evolutionary limits. This project aims to understand the processes that limit adaptation to rapid environmental change. Adaption to rapid environmental change determines population persistence. Species with restricted distributions may lack the genetic variation necessary to adapt to changing environments, although they represent the vast majority of biodiversity. Understanding why they lack the necessary genetic variation for adaptation is important for identifying and managing vulnerable biolo ....Evolutionary limits. This project aims to understand the processes that limit adaptation to rapid environmental change. Adaption to rapid environmental change determines population persistence. Species with restricted distributions may lack the genetic variation necessary to adapt to changing environments, although they represent the vast majority of biodiversity. Understanding why they lack the necessary genetic variation for adaptation is important for identifying and managing vulnerable biological systems. This project will empirically determine the contribution of mutations to key traits to better understand what limits evolutionary adaptation. Better prediction of extinction risk should inform conservation and biodiversity management.Read moreRead less
Integrating evolution and plasticity into predictions of population persistence in a changing climate: adaptation or extinction? To effectively manage biodiversity at a time of rapid environmental change, Australia needs accurate predictions of how human alterations to climate and habitat will affect species. This project integrates evolution and spatial ecology to develop new tools for predicting and understanding how species will respond to environmental change.
The evolutionary biology of seminal fluid. This project will identify proteins within seminal fluid that impact sperm performance and male fertility. The work will derive new insights into the evolution of seminal fluid proteins, while simultaneously exploring how environmental factors such as diet impact male fertility in animals and humans.
Discovery Early Career Researcher Award - Grant ID: DE120102630
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
The neurological correlates of periodic breathing in insects. While at rest many animals switch from breathing continuously to displaying long breath-hold periods between periods of ventilation. The neurological mechanisms responsible for generating this respiratory pattern will be investigated using insects that display a discontinuous pattern of breathing.
Functional evolution and therapeutic potential of snake venom coagulotoxins. This project aims to identify and understand the factors that influence the useful function of key residues (parts of larger compounds) in Australian snake venom coagulotoxins, which alter blood-clotting ability. In recent years, snake venom compounds have been demonstrated as useful models from which to synthesise therapeutic drugs to improve health and well-being. This project will test these important toxins on model ....Functional evolution and therapeutic potential of snake venom coagulotoxins. This project aims to identify and understand the factors that influence the useful function of key residues (parts of larger compounds) in Australian snake venom coagulotoxins, which alter blood-clotting ability. In recent years, snake venom compounds have been demonstrated as useful models from which to synthesise therapeutic drugs to improve health and well-being. This project will test these important toxins on model systems that represent natural prey items in order to determine the molecular and functional evolution of blood-clot forming enzymes. Expected outcomes include substantial contributions to the body of evolutionary biology knowledge, as well as narrowing the search for the ultimate drug candidates.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101853
Funder
Australian Research Council
Funding Amount
$356,000.00
Summary
One genome but two sexes: Conflict and the evolution of sexual dimorphism. How can males and females display striking sex differences, when they primarily share the same set of genes? By experimentally evolving the degree of sexual dimorphism in Drosophila melanogaster, this project endeavours to address key issues at the heart of evolutionary biology. This project aims to deliver a novel, data-rich resource with which to explore the mechanisms and consequences of sexual dimorphism evolution, to ....One genome but two sexes: Conflict and the evolution of sexual dimorphism. How can males and females display striking sex differences, when they primarily share the same set of genes? By experimentally evolving the degree of sexual dimorphism in Drosophila melanogaster, this project endeavours to address key issues at the heart of evolutionary biology. This project aims to deliver a novel, data-rich resource with which to explore the mechanisms and consequences of sexual dimorphism evolution, to expand current understanding of this fundamental evolutionary paradox.Read moreRead less
Comparative Paleogenomics of the Arctic Tundra Ecosystem: the genetic response of plants and animals to climate change. This project will use DNA from deep-frozen seeds and bones 100,000 years old to record how species respond to climate change - by adapting and surviving or by shifting ranges and moving. Very large numbers of genes will be examined to identify changes across the genomes of four plant and two animal species, and contrast the responses to major climatic shifts.
Experimental co-evolution of Yeast and E. coli. This project aims to measure the rates and genetic mechanisms of adaptation for individual species within a microbial community. Expected outcomes of this interdisciplinary project include the first genomic and phenotypic dataset of a model microbial community, and novel tools for the analysis of meta-genomic datasets. This project has the potential to transform understanding of microbial adaptation.
Experimental evolution in the mitochondrion. This project aims to discover if the genetic variation in mitochondria (our energy centres) contributes to evolutionary adaptation. This is a long-debated hypothesis in evolutionary biology. This project will take an inter-disciplinary approach, involving experimental evolution, an ecological framework, the measurement of organismal physiologies, and fruit fly genetics. The outcomes could change how biologists view the mitochondria, reveal mitochondri ....Experimental evolution in the mitochondrion. This project aims to discover if the genetic variation in mitochondria (our energy centres) contributes to evolutionary adaptation. This is a long-debated hypothesis in evolutionary biology. This project will take an inter-disciplinary approach, involving experimental evolution, an ecological framework, the measurement of organismal physiologies, and fruit fly genetics. The outcomes could change how biologists view the mitochondria, reveal mitochondria’s role in adaptation to climatic stress, and their contribution to shaping evolutionary trade-offs and conflict between the sexes.Read moreRead less