Understanding somatic mutation in plants: new methods, new software, new data. Somatic mutations accumulate as plants grow, affecting everything from short-term ecological interactions to long-term evolutionary dynamics. These mutations have important consequences for plant industry and conservation, but because they are so hard to measure almost nothing is known about them. This project aims to develop new methods and software to detect, analyse, and compare the genome-wide history of somatic m ....Understanding somatic mutation in plants: new methods, new software, new data. Somatic mutations accumulate as plants grow, affecting everything from short-term ecological interactions to long-term evolutionary dynamics. These mutations have important consequences for plant industry and conservation, but because they are so hard to measure almost nothing is known about them. This project aims to develop new methods and software to detect, analyse, and compare the genome-wide history of somatic mutation in individual plants, providing an unprecedented level of detail into an important but understudied source of biological variation. By applying these methods to an iconic experimental population, This project aims to provide the first insights into the genome-wide causes and consequences of somatic mutation in plants.Read moreRead less
Learning Software Security Analysers with Imperfect Data. This project aims to systematically investigate next-generation learning-based software security analysis to detect vulnerabilities in real-world large-scale software. The expected learning-based foundation will support the handling of imperfect data in order to provide a precise, scalable and adaptive security analysis of the critical software components, thus capturing important security vulnerabilities missed by existing approaches. Th ....Learning Software Security Analysers with Imperfect Data. This project aims to systematically investigate next-generation learning-based software security analysis to detect vulnerabilities in real-world large-scale software. The expected learning-based foundation will support the handling of imperfect data in order to provide a precise, scalable and adaptive security analysis of the critical software components, thus capturing important security vulnerabilities missed by existing approaches. The success of this project will further enhance the international competitiveness of Australian research in this important field and will benefit any Australian industry and business where software systems are deeply-rooted, such as transportation, smart homes, medical devices, defence and finance.Read moreRead less
Evolution and functional impact of gene silencing by hairpin derived RNAs. This project aims to study RNA-mediated gene silencing in genome evolution. RNA interference (RNAi) has been widely used as an experimental tool since its Nobel Prize-winning discovery in 1998, but little is known about endogenous RNAi or its evolution. This project uses bioinformatics, high-throughput sequencing and molecular approaches to study hpRNAs, a class of small interfering RNAs, their adaptive evolution across f ....Evolution and functional impact of gene silencing by hairpin derived RNAs. This project aims to study RNA-mediated gene silencing in genome evolution. RNA interference (RNAi) has been widely used as an experimental tool since its Nobel Prize-winning discovery in 1998, but little is known about endogenous RNAi or its evolution. This project uses bioinformatics, high-throughput sequencing and molecular approaches to study hpRNAs, a class of small interfering RNAs, their adaptive evolution across fly species and vertebrates, and their functional effect on testis morphogenesis and distortion of female/male sex-ratio. The project also studies splicing-dependent small RNAs and miRNA-target interaction. This research could have applications from animal development to human pathology.Read moreRead less
Advanced Interface Technologies for Computational Science & Simulation. The project will research novel computer vision technologies that enable the next generation of visualisation portals for scientific collaboration. The development of new computer vision tools is key to truly natural human-machine interaction. The research outcomes of this project directly align with National Research Priority 3: Frontier Technologies. It supports four of the five relevant priority goals - Breakthrough Scien ....Advanced Interface Technologies for Computational Science & Simulation. The project will research novel computer vision technologies that enable the next generation of visualisation portals for scientific collaboration. The development of new computer vision tools is key to truly natural human-machine interaction. The research outcomes of this project directly align with National Research Priority 3: Frontier Technologies. It supports four of the five relevant priority goals - Breakthrough Science, Frontier Technologies, Smart Information Use, and Promoting an Innovation Culture and Economy. Outcomes of this research are also relevant to Research Priority 4: Safeguarding Australia, and has direct applications to video surveillance technology. Significant commercial opportunities, including licensing and spin-offs exist.Read moreRead less
Engineering Artificial Intelligence: A Spatial Representation and Reasoning Perspective. Spatial information is important in areas of national interest such as mining and exploration, environmental monitoring and planning, emergency response, and defence. Mission control centres, for instance, receive different forms of spatial data from satellites, radar, or people on the ground. They have to process the input data and make intelligent decisions in a very limited time. Intelligent systems that ....Engineering Artificial Intelligence: A Spatial Representation and Reasoning Perspective. Spatial information is important in areas of national interest such as mining and exploration, environmental monitoring and planning, emergency response, and defence. Mission control centres, for instance, receive different forms of spatial data from satellites, radar, or people on the ground. They have to process the input data and make intelligent decisions in a very limited time. Intelligent systems that are able to assist with processing different forms of spatial data efficiently and that offer reliable decision support are essential for improving the quality and reliability of such applications. This research enables future intelligent systems with these capabilities. This will directly benefit applications in areas of national interest.Read moreRead less
Controlling ultracold atomic gases. This project will develop ways to control the quantum state of ultracold atomic gases. These experimentally accessible systems will be used to investigate and understand a huge range of scientific phenomena from stars to superconductors, and enable critical quantum technologies that will revolutionise communications and precision measurement.