Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlyin ....Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlying biological and biomedical processes, bringing sustainable discovery of new relationships and variations within the data. The project aims to support new approaches to medical diagnosis and treatment, and offer crucial lessons to address the broader challenge of understanding large, complex data sets.Read moreRead less
Next-generation genomic resources to tackle parasitic diseases of animals. The revolution in genomics provides unprecedented opportunities to tackle destructive parasitic diseases affecting billions of animals worldwide. Through a synergy of leading-edge technologies and a strong partnership with BGI International, this project aims to deliver major conceptual advances in the understanding of parasitism; an unparalleled skills-base in genomics and bioinformatics; innovative new molecular technol ....Next-generation genomic resources to tackle parasitic diseases of animals. The revolution in genomics provides unprecedented opportunities to tackle destructive parasitic diseases affecting billions of animals worldwide. Through a synergy of leading-edge technologies and a strong partnership with BGI International, this project aims to deliver major conceptual advances in the understanding of parasitism; an unparalleled skills-base in genomics and bioinformatics; innovative new molecular technologies; and new treatments and diagnostic tests as biotechnological outcomes. This leap forward in Australia will substantially enhance the global profile of parasitology research, training and employment opportunities for early career scientists, and improve access to international research funding and networks. Read moreRead less
Smart algorithms for visual field assessment. Australian demographic studies show that visual impairment contributes significantly to elderly disability. Visual field loss due to glaucoma, the second leading cause of blindness in developed nations, may be slowed if detected early, but recent studies estimate 50% of Australians with glaucoma are undiagnosed. The fast and effective approaches to measuring visual fields discovered in this project will allow more accurate diagnosis and monitoring of ....Smart algorithms for visual field assessment. Australian demographic studies show that visual impairment contributes significantly to elderly disability. Visual field loss due to glaucoma, the second leading cause of blindness in developed nations, may be slowed if detected early, but recent studies estimate 50% of Australians with glaucoma are undiagnosed. The fast and effective approaches to measuring visual fields discovered in this project will allow more accurate diagnosis and monitoring of vision loss; crucial for the ARC's priority goals of "ageing well, ageing productively" and "preventative healthcare". Developing smart algorithms in conjunction with Heidelberg Engineering creates an opportunity for the international promotion of Australia's biomedical software capabilities.Read moreRead less
Effective software process improvement in a large-scale defence contracting environment. Most organisations struggle to consistently develop high-quality software on schedule and within budget. Continuing changes in technologies and customer expectations complicate this challenge. Software process improvement frameworks aim to guide organisations towards best practice. This project will assess practical experience with individual software process improvement frameworks in a large-scale defence c ....Effective software process improvement in a large-scale defence contracting environment. Most organisations struggle to consistently develop high-quality software on schedule and within budget. Continuing changes in technologies and customer expectations complicate this challenge. Software process improvement frameworks aim to guide organisations towards best practice. This project will assess practical experience with individual software process improvement frameworks in a large-scale defence contracting environment, with the goal of developing an effective strategy for integrating them. The outcomes will include documented experience with specific process improvement frameworks and a strategy for an overall framework that combines them.Read moreRead less
Real-time phylogenetics for food-borne outbreak surveillance. The project aims to introduce, for the first time, real-time evolutionary analysis of agricultural pathogens so that outbreaks affecting crops and the food supply can be managed precisely and rapidly. An expert team will implement a large-scale data analytics framework in user-friendly software that integrates Australian infectious disease genomics data with global data. Underpinning this work are new theory and algorithms that apply ....Real-time phylogenetics for food-borne outbreak surveillance. The project aims to introduce, for the first time, real-time evolutionary analysis of agricultural pathogens so that outbreaks affecting crops and the food supply can be managed precisely and rapidly. An expert team will implement a large-scale data analytics framework in user-friendly software that integrates Australian infectious disease genomics data with global data. Underpinning this work are new theory and algorithms that apply Sequential Monte Carlo to update phylogenetic analyses continuously as new data arrives. Expected outcomes include new knowledge of statistical algorithms for evolutionary analysis, relevant to biological disciplines beyond infectious disease; and enhanced capacity for infectious disease analysis. Read moreRead less
Reducing the risks associated with developing large-scale, critical software-integrated systems. Industry, government and defence increasingly rely on large-scale, critical software-integrated systems. The scale and complexity of these systems means current methods of analysing, designing and assuring their dependability are struggling to provide the constructive support and assurance that is demanded. Consequently, there are significant risks of cost and schedule overruns and of system problems ....Reducing the risks associated with developing large-scale, critical software-integrated systems. Industry, government and defence increasingly rely on large-scale, critical software-integrated systems. The scale and complexity of these systems means current methods of analysing, designing and assuring their dependability are struggling to provide the constructive support and assurance that is demanded. Consequently, there are significant risks of cost and schedule overruns and of system problems and failures. This project builds on results from our current collaboration - a new method for modelling, analysis and defect detection for the requirements of large-scale systems. We will develop and scale-up to industry strength, simpler, more powerful, strategies for analysing, designing and providing the high level of assurance required.Read moreRead less
Achieving Tailored Industrial Software Process Improvement with Experience Repositories and Electronic Process Guides. There is a well-recognised need for organisations to improve their software development processes in order to achieve higher software quality and greater efficiencies in development. The use of electronic process guides and experience repositories have been two technologies independently proposed to achieve these aims. This research will develop a framework, methods and tools ....Achieving Tailored Industrial Software Process Improvement with Experience Repositories and Electronic Process Guides. There is a well-recognised need for organisations to improve their software development processes in order to achieve higher software quality and greater efficiencies in development. The use of electronic process guides and experience repositories have been two technologies independently proposed to achieve these aims. This research will develop a framework, methods and tools to allow integration of experience repositories and electronic process guides to facilitate process tailoring, process improvement, and project management. The result will be significant improvements in software development productivity and quality.Read moreRead less
Eat and Dream: effective automatic testing and debugging for real-life embedded wireless communications software. Embedded software is a key enabling technology for the majority of Australian manufacturing industries, including strategically important sectors such as the automotive industry. Embedded wireless communication technologies are playing an increasingly significant role in Australia with a wide range of critical applications ranging from natural disaster early warning to personal healt ....Eat and Dream: effective automatic testing and debugging for real-life embedded wireless communications software. Embedded software is a key enabling technology for the majority of Australian manufacturing industries, including strategically important sectors such as the automotive industry. Embedded wireless communication technologies are playing an increasingly significant role in Australia with a wide range of critical applications ranging from natural disaster early warning to personal health monitoring. Embedded wireless communications software, however, is difficult to test and debug owing to the complexity of the operational environment and complications arising from the interplay between software and hardware. This project will develop an effective and automatic technology to alleviate these difficulties and achieve higher quality software.Read moreRead less
A Generic Software Architecture for Web-Based Applications on Micro-Mobile Systems. The next generation of computers that will capture the imagination of the society are likely to be micro-mobile devices such as personal digital assistants, mobile phones, smartcards and chips embedded in home and office items. Developing applications for information processing using a wireless network of such devices is an emerging challenge. This project will develop and evaluate a generic architecture for web- ....A Generic Software Architecture for Web-Based Applications on Micro-Mobile Systems. The next generation of computers that will capture the imagination of the society are likely to be micro-mobile devices such as personal digital assistants, mobile phones, smartcards and chips embedded in home and office items. Developing applications for information processing using a wireless network of such devices is an emerging challenge. This project will develop and evaluate a generic architecture for web-based applications on micro-mobile devices. This will make it easy to design applications that can seamlessly interact with different kinds of devices. The project will be carried out in partnership with Total Internet Centre, a Newcastle based regional enterprise.Read moreRead less
Formal modelling and analysis of software requirements for air traffic management systems for improved integrity assurance. This project will significantly reduce the time and cost of developing software for critical applications such as aviation and air traffic management. As well as improving the trustworthiness of safety-critical computer-based systems, this project will also enable system improvements to be deployed faster and more reliably.