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Molecular Analysis Of Endocarditis Causing Strains Of Staphylococcus Aureus
Funder
National Health and Medical Research Council
Funding Amount
$110,960.00
Summary
"Staphylococcus aureus" or "Golden Staph” is one of the principal causes of infective endocarditis, the infection of the endocardial surfaces of the heart and heart valves that may result in valvular insufficiency and eventual heart failure. This work will define the molecular mechanisms that allow S. aureus to survive and persist on endocardial surfaces. Such insight may lead to new future treatment regimes for infective endocarditis.
Early Origins Study Of Cystic Fibrosis-related Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$128,188.00
Summary
Cystic Fibrosis is a genetic condition that causes recurrent lung infections and early death. Some patients also develop diabetes which causes a more rapid decline. Many young children with CF have “pre-diabetes” but guidelines do not recommend screening high glucose in this group. In order to intervene early, this study aims to determine if “pre-diabetes” in very young children with Cystic Fibrosis causes poorer growth, lung function or an increase in bacterial infections to.
Design And Implementation Of A Human Challenge Model For Neisseria Gonorrhoeae
Funder
National Health and Medical Research Council
Funding Amount
$132,743.00
Summary
Gonorrhoea is a major public health problem that can lead to severe disease and promote the spread of HIV. Gonorrhoea infections are increasing worldwide and the spread of antibiotic resistant gonorrhoea is a critical health threat. This study aims to develop a controlled infection model for male throat and genital gonorrhoea infection in order to improve scientific understanding of gonorrhoea infection and responses to novel antibiotic treatment; and provide insights into vaccine development.
Rapid Point-of-Care (POC) Tests For Sexually Transmitted Infections (STIs): Evaluation Of Accuracy, Acceptability And Impact In Australia And Papua New Guinea (PNG)
Funder
National Health and Medical Research Council
Funding Amount
$99,883.00
Summary
This research, composed of three studies, aims to evaluate rapid point-of-care tests for selected sexually transmitted infections (including syphilis, Chlamydia and gonorrhoea) to determine their accuracy and acceptability, their potential role in and impact on control of STIs in Papua New Guinea and remote settings in Australia.
Exploring HIV Sexual Risk Behaviours Among ‘hidden’ MSM In Myanmar And Opportunities To Improve Health Through Information Communication Technology (ICT) Platforms
Funder
National Health and Medical Research Council
Funding Amount
$92,364.00
Summary
This research will describe sexual risk behaviours and perceptions of HIV vulnerability among 'hidden' MSM in Myanmar. It will characterise their sexual and social networks with both male and female partners, as well as identify barriers to accessing sexual health and HIV testing and support services. This study will also assess the potential for digital technology to deliver sexual health promotion and facilitate service access among hidden MSM in Myanmar.
Treatment Of Rectal Chlamydia Infection In Gay And Bisexual Men
Funder
National Health and Medical Research Council
Funding Amount
$64,713.00
Summary
Rectal chlamydia is very common in gay men; it can exist for long periods without symptoms leading to ongoing transmission. There are two choices for antibiotic treatment: azithromycin and doxycycline, but there is uncertainty about which is more effective. This research will determine which treatment is best and what the economic implications are. The findings will update treatment guidelines and ensure that the most effective treatment is used to prevent ongoing transmission.
The HIV Treatment Cascade: Improved Individual And Population Health Outcomes Through A Better Understanding Of The Natural History Of HIV And Its Treatment In Modern Health Care Systems.
Funder
National Health and Medical Research Council
Funding Amount
$93,124.00
Summary
To review the methodologies used to analyse the HIV care and treatment cascade in different settings and their limitations. To identify, design and evaluate pilot interventions to improve individual and population outcomes. I am not currently working on any research that requires ethics clearance.
Sexually Transmitted Infections(STIs) And Co Transmission Of HIV In Men Who Have Sex With Men. The Presence Of STIs In The Rectum And Its Effect On HIV Viral Load Independent Of Anti-retroviral Treatment In HIV
Funder
National Health and Medical Research Council
Funding Amount
$137,721.00
Summary
I am a trainee sexual health physician with a special interest in sexually transmitted infections (STIs) and how it influences HIV transmission between men who have sex with men(MSM). I intend to achieve this by conducting research to help better define the causes of rectal STIs in MSM and what can be done to detect and treat them early. This will hopefully lead to a decrease in HIV transmission in a group who are at higher risk for STI/HIV infections and hence improve their overall health.
Working Conditions, Job Stress And Mental Health Of Family Day Care Providers: Implications For Quality Of Caregiving.
Funder
National Health and Medical Research Council
Funding Amount
$93,630.00
Summary
Over 100,000 children attend family day care in the homes of 12,000 providers in Australia. Family day carers work under challenging conditions and many carers leave the profession annually. The working conditions, mental health and job stress of family day carers and how their mental health may relate to quality of care has not been investigated. This PhD study will examine these issues and explore if and how a systems approach can improve family day carer mental health and job satisfaction.
THE EFFECT OF LONG ACTING BRONCHODILATORS ON VENTILATION IN COPD
Funder
National Health and Medical Research Council
Funding Amount
$143,676.00
Summary
COPD is a common and important smoking-related lung disease. Well-established treatments with inhaled medications including long-acting bronchodilators have a proven clinical track record. However the physiological basis for their effects is still under investigation. This research examines some of the physiological changes in lung function and the response to long-acting bronchodilators in patients with COPD, and may help explain why some patients respond to therapy while others do not, leading ....COPD is a common and important smoking-related lung disease. Well-established treatments with inhaled medications including long-acting bronchodilators have a proven clinical track record. However the physiological basis for their effects is still under investigation. This research examines some of the physiological changes in lung function and the response to long-acting bronchodilators in patients with COPD, and may help explain why some patients respond to therapy while others do not, leading to more targeted therapeuticsRead moreRead less