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Improving plant productivity and human health using next generation biotechnology approaches. Both medical and plant sciences face similar technological problems in harnessing the power of modern DNA sequencing for accelerating the pace of beneficial gene function discovery. Plant and animal researchers will collaborate in this program to meet this common challenge. The research outcomes envisaged in this proposal will benefit human health by enabling more rapid discovery of genes related to obe ....Improving plant productivity and human health using next generation biotechnology approaches. Both medical and plant sciences face similar technological problems in harnessing the power of modern DNA sequencing for accelerating the pace of beneficial gene function discovery. Plant and animal researchers will collaborate in this program to meet this common challenge. The research outcomes envisaged in this proposal will benefit human health by enabling more rapid discovery of genes related to obesity, immunity, fertility, neurological function and cancer. In the plant sphere, the outcomes will shed new light on plant functions related to plant energy metabolism, vitamin biosynthesis drought tolerance and water use by crops. The research will benefit both human health and agricultural food production and quality.Read moreRead less
Future Industries Research - Biotechnology and Nanotechnology: Small talk: Communication networks in microbes. We will use the Australian Proteome Analysis Facility to address the multifaceted mechanisms of microbial interactions and produce new knowledge about the pathogen Pseudomonas aeruginosa, a common cause of death in cystic fibrosis patients. We will characterise the interactions between P. aeruginosa and the emerging fungal pathogen Scedosporium aurantiacum as a proactive step towards be ....Future Industries Research - Biotechnology and Nanotechnology: Small talk: Communication networks in microbes. We will use the Australian Proteome Analysis Facility to address the multifaceted mechanisms of microbial interactions and produce new knowledge about the pathogen Pseudomonas aeruginosa, a common cause of death in cystic fibrosis patients. We will characterise the interactions between P. aeruginosa and the emerging fungal pathogen Scedosporium aurantiacum as a proactive step towards better understanding of pathogen communication. Improved understanding of pathogen interactions should facilitate the development of novel anti-adhesives as therapeutics. Our project will train young scientists in a new integrated approach to biology.Read moreRead less
Developing biotechnology solutions for improving phosphate acquisition in plants using functional genomics in rice. Global supplies of the most currently used phosphate fertilisers are predicted to be exhausted in less than a century. These fertilisers are non-renewable resources based on phosphate rock deposits and their use are key drivers of both plant production costs and environmental damage in Australia and internationally. Using the power of genetic and functional genomics analyses in ric ....Developing biotechnology solutions for improving phosphate acquisition in plants using functional genomics in rice. Global supplies of the most currently used phosphate fertilisers are predicted to be exhausted in less than a century. These fertilisers are non-renewable resources based on phosphate rock deposits and their use are key drivers of both plant production costs and environmental damage in Australia and internationally. Using the power of genetic and functional genomics analyses in rice, this project will reveal key controllers of phosphate acquisition in plants. Hence, novel biotechnology based solutions can be implemented in a variety of cereal crops to aid reduced use of phosphate fertiliser in agriculture and unlock the large phosphate pool not used by plants in soil.Read moreRead less
Design and Fabrication of Molecular Machines: the Nanomachines of the Future. Nanotechnology that incorporates the use of nanomachines and molecular machines is an exciting new area of translational research, with broad potential in biomedical technology and industrial applications. We are developing new molecular machines and optimising their assembly. Recent innovation in the world of nanotechnology concerns the design and manufacture of synthetic and hybrid machines, based on existing biologi ....Design and Fabrication of Molecular Machines: the Nanomachines of the Future. Nanotechnology that incorporates the use of nanomachines and molecular machines is an exciting new area of translational research, with broad potential in biomedical technology and industrial applications. We are developing new molecular machines and optimising their assembly. Recent innovation in the world of nanotechnology concerns the design and manufacture of synthetic and hybrid machines, based on existing biological molecular machines but incorporating synthetic parts. Australia has an opportunity to be at the forefront of these new developments in nanotechnology, with a new generation of Australian scientists being trained across the foundation disciplines of chemistry, physics and molecular biology.Read moreRead less
Extreme expression: building a platform for industrial plant biotechnology. Plants have remarkable potential as bioreactors for the production of usually non-plant compounds such as medical proteins, industrial proteins including enzymes and polymers. However, to realise this potential, there needs to be very significant advances in the amount of target compounds produced in the bioreactor plants and to develop other plant species as bioreactors. The aim of this project is to develop technologie ....Extreme expression: building a platform for industrial plant biotechnology. Plants have remarkable potential as bioreactors for the production of usually non-plant compounds such as medical proteins, industrial proteins including enzymes and polymers. However, to realise this potential, there needs to be very significant advances in the amount of target compounds produced in the bioreactor plants and to develop other plant species as bioreactors. The aim of this project is to develop technologies that provide the platform to produce large quantities of target novel compounds in plants and extend the range of plant species that can be used as bioreactors. These technologies will provide the basis of a dynamic biofarming industry in Australia.Read moreRead less
Pelagic ecosystem linkages in a changing Southern Ocean. Our study, which aims to better describe and understand the ecology of the vast Ocean to the south of Australia, will provide the information that will assist in managing this region in an era of change. Many species are of significant conservation concern, others are recovering from previous harvesting, some are being harvested and all will be affected by a changing climate. Understanding the ecosystem linkages and the way in which the p ....Pelagic ecosystem linkages in a changing Southern Ocean. Our study, which aims to better describe and understand the ecology of the vast Ocean to the south of Australia, will provide the information that will assist in managing this region in an era of change. Many species are of significant conservation concern, others are recovering from previous harvesting, some are being harvested and all will be affected by a changing climate. Understanding the ecosystem linkages and the way in which the physical environment affects the distribution and abundance of key ecosystem components will allow us to better manage the system and to predict the effects of future climate change. Read moreRead less
Supporting early science from the Murchison Widefield Array - a Square Kilometre Array (SKA) pathfinder telescope. The Murchison Widefield Array (MWA) is likely to be the first operational pathfinder for the $2.5 billion Square Kilometre Array (SKA) on one of the two candidate SKA sites - the Murchison Radioastronomy Observatory (MRO) in Western Australia. The MWA will therefore generate large volumes of scientific data before 2012, the expected date of the international decision that will dete ....Supporting early science from the Murchison Widefield Array - a Square Kilometre Array (SKA) pathfinder telescope. The Murchison Widefield Array (MWA) is likely to be the first operational pathfinder for the $2.5 billion Square Kilometre Array (SKA) on one of the two candidate SKA sites - the Murchison Radioastronomy Observatory (MRO) in Western Australia. The MWA will therefore generate large volumes of scientific data before 2012, the expected date of the international decision that will determine whether Australia or South Africa is to host the SKA. The early science results from the MWA will showcase the excellence of the Australian site for radio astronomy and play a significant strategic role in Australia's bid to attract the SKA, as an international mega-science project to Australia, with its benefits to Australian science, industry and society.Read moreRead less
Supporting early science from the Murchison Widefield Array - a Square Kilometre Array (SKA) pathfinder telescope. The Murchison Widefield Array (MWA) is likely to be the first operational pathfinder for the $2.5 billion Square Kilometre Array (SKA) on one of the two candidate SKA sites - the Murchison Radioastronomy Observatory (MRO) in Western Australia. The MWA will therefore generate large volumes of scientific data before 2012, the expected date of the international decision that will dete ....Supporting early science from the Murchison Widefield Array - a Square Kilometre Array (SKA) pathfinder telescope. The Murchison Widefield Array (MWA) is likely to be the first operational pathfinder for the $2.5 billion Square Kilometre Array (SKA) on one of the two candidate SKA sites - the Murchison Radioastronomy Observatory (MRO) in Western Australia. The MWA will therefore generate large volumes of scientific data before 2012, the expected date of the international decision that will determine whether Australia or South Africa is to host the SKA. The early science results from the MWA will showcase the excellence of the Australian site for radio astronomy and play a significant strategic role in Australia's bid to attract the SKA, as an international mega-science project to Australia, with its benefits to Australian science, industry and society.Read moreRead less
The Galaxy Genome Project 2. The Galaxy Genome Project builds on the Anglo-Australian Observatory's (AAO) major investments and world-leading strengths in wide-field survey astronomy and multi-object spectrographs. Combining the AAO's ongoing and planned survey programs with data from other new Australian facilities, such as SkyMapper and Australian Square Kilometre Array Pathfinder, will increase the scientific productivity and impact of all of these major Australian investments and leverage ac ....The Galaxy Genome Project 2. The Galaxy Genome Project builds on the Anglo-Australian Observatory's (AAO) major investments and world-leading strengths in wide-field survey astronomy and multi-object spectrographs. Combining the AAO's ongoing and planned survey programs with data from other new Australian facilities, such as SkyMapper and Australian Square Kilometre Array Pathfinder, will increase the scientific productivity and impact of all of these major Australian investments and leverage access for Australian researchers in other leading international astronomical surveys and facilities. The project will also increase the international profile of Australian astronomy and enhance the prospects of Australian scientific and technical involvement in next-generation astronomical facilities such as Square Kilometre Array and Giant Magellan Telescope.Read moreRead less
The Galaxy Genome Project 1. The Galaxy Genome Project builds on the Anglo-Australian Observatory's (AAO) major investments and world-leading strengths in wide-field survey astronomy and multi-object spectrographs. Combining the AAO's ongoing and planned survey programs with data from other new Australian facilities, such as SkyMapper and Australian Square Kilometre Array Pathfinder, this project will increase the scientific productivity and impact of all of these major Australian investments an ....The Galaxy Genome Project 1. The Galaxy Genome Project builds on the Anglo-Australian Observatory's (AAO) major investments and world-leading strengths in wide-field survey astronomy and multi-object spectrographs. Combining the AAO's ongoing and planned survey programs with data from other new Australian facilities, such as SkyMapper and Australian Square Kilometre Array Pathfinder, this project will increase the scientific productivity and impact of all of these major Australian investments and leverage access for Australian researchers in other leading international astronomical surveys and facilities. The project will also increase the international profile of Australian astronomy and enhance the prospects of Australian scientific and technical involvement in next-generation astronomical facilities such as Square Kilometre Array and Giant Magellan Telescope.Read moreRead less