Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing an ....Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing and reduced-order state observer, supported by lab/plant experiments, and collaborating with two industry partners from coal and steel industries. The project outcomes including codes, models and raceway control strategies can help promote Australian metallurgical coal's global markets and ultimately the Australian economy.Read moreRead less
Expectations and commitments in the Australia-USA alliance. This project aims to investigate the gap between the high expectations of mutual support and the lack of detailed security commitments in the Australia-US Alliance. The project intends to use a focused approach that captures thematic aspects of the alliance through project frames and historical slices across time. Expected outcomes can advance understanding of how alliances operate as security institutions. The outcomes can help to prom ....Expectations and commitments in the Australia-USA alliance. This project aims to investigate the gap between the high expectations of mutual support and the lack of detailed security commitments in the Australia-US Alliance. The project intends to use a focused approach that captures thematic aspects of the alliance through project frames and historical slices across time. Expected outcomes can advance understanding of how alliances operate as security institutions. The outcomes can help to promote a more informed national conversation about the costs and benefits of Australia's security relationship with the United States of America (USA) and contribute to debates over the future of the Australia-USA Alliance during a period of strategic uncertainty.Read moreRead less
New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry suppl ....New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry supply and sales network. This project seeks to identify and harness the key material-product attributes required to develop and implement new, lead-free alloy alternatives that meet health-compliance, production and commercial viability, that offer benefits across the industry network and health benefits to society.Read moreRead less
Special Research Initiatives - Grant ID: SR180100005
Funder
Australian Research Council
Funding Amount
$1,225,000.00
Summary
Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The proj ....Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The project will provide a scientific basis for understanding the benefits and limitations associated with soil washing and immobilisation techniques and a more comprehensive understanding of future liabilities associated with formation of PFASs from precursors remaining in remediated soils. Collaboration with stakeholders will ensure benefits are captured both commercially and environmentally, as well as removing a potential and on-going health threat to communities exposed to these contaminants.Read moreRead less
Radical right populist parties. This project aims to explain why some radical right-wing populists in Western democracies enter governmental alliances with mainstream parties while others remain isolated. The emergence, spread and electoral success of radical right populists is a problem facing liberal democracy in the twenty-first century. While these parties’ policies, ideologies and rhetoric are similar, their relationships with mainstream parties are different. By examining explanatory facto ....Radical right populist parties. This project aims to explain why some radical right-wing populists in Western democracies enter governmental alliances with mainstream parties while others remain isolated. The emergence, spread and electoral success of radical right populists is a problem facing liberal democracy in the twenty-first century. While these parties’ policies, ideologies and rhetoric are similar, their relationships with mainstream parties are different. By examining explanatory factors that Political Science studies have so far been neglected, this project seeks to explain this variation and explore its implications for coalition theory.Read moreRead less
Evaluating the impact of neuromusculoskeletal impairment on athletic performance. Sufficient physical activity is required for good health. Competitive sport is a culturally significant physical activity in Australia and the prospect of participating in fair competition is known to drive participation. In Paralympic sport, fair competition is enabled by classification, which aims to minimise the impact of impairments on competition outcome. Unfortunately classification methods are not evidence-b ....Evaluating the impact of neuromusculoskeletal impairment on athletic performance. Sufficient physical activity is required for good health. Competitive sport is a culturally significant physical activity in Australia and the prospect of participating in fair competition is known to drive participation. In Paralympic sport, fair competition is enabled by classification, which aims to minimise the impact of impairments on competition outcome. Unfortunately classification methods are not evidence-based, reducing confidence in the process and discouraging participation. This project will inform the development of the first evidence-based classification system, creating the possibility that, in the future, the prospect of truly fair competition may motivate sports participation among Australians, regardless of disability.Read moreRead less
The impact of political reconciliation in the Asia-Pacific. Focusing on the cases of East Timor, Bougainville and the Solomon Islands, this project will examine the contribution that political reconciliation processes, practices and events make to the pursuit of peace and security in the Asia-Pacific. Using a highly contextual, interpretive approach grounded in intensive in-country fieldwork, it will provide an empirically grounded assessment of regional reconciliation processes that not only co ....The impact of political reconciliation in the Asia-Pacific. Focusing on the cases of East Timor, Bougainville and the Solomon Islands, this project will examine the contribution that political reconciliation processes, practices and events make to the pursuit of peace and security in the Asia-Pacific. Using a highly contextual, interpretive approach grounded in intensive in-country fieldwork, it will provide an empirically grounded assessment of regional reconciliation processes that not only contributes to the development of scholarly literature on transitional justice, peacebuilding and security, but also to contemporary policy debates concerning Australia’s engagement with states within its immediate regional neighbourhood.Read moreRead less
Amnesties and peace accords in the Asia-Pacific. This project aims to produce a comprehensive empirical study of peace-settlement amnesties and their impact on democracy, human rights and long-term peace in the aftermath of violent con?ict. It combines a large-scale global study of all amnesties included in peace accords from 1980 to 2005 with four case studies drawn from the Asia-Paci?c region: Indonesia/Aceh; Papua New Guinea/Bougainville; East Timor; and the Solomon Islands. It will provide a ....Amnesties and peace accords in the Asia-Pacific. This project aims to produce a comprehensive empirical study of peace-settlement amnesties and their impact on democracy, human rights and long-term peace in the aftermath of violent con?ict. It combines a large-scale global study of all amnesties included in peace accords from 1980 to 2005 with four case studies drawn from the Asia-Paci?c region: Indonesia/Aceh; Papua New Guinea/Bougainville; East Timor; and the Solomon Islands. It will provide an original contribution to scholarship concerned with amnesties and peace- settlements as well as crucial and as yet unavailable insights into the effectiveness and broader rami?cations of offering amnesties in exchange for peace that will inform future peacemaking practice.Read moreRead less