Molecular Analysis Of Endocarditis Causing Strains Of Staphylococcus Aureus
Funder
National Health and Medical Research Council
Funding Amount
$110,960.00
Summary
"Staphylococcus aureus" or "Golden Staph” is one of the principal causes of infective endocarditis, the infection of the endocardial surfaces of the heart and heart valves that may result in valvular insufficiency and eventual heart failure. This work will define the molecular mechanisms that allow S. aureus to survive and persist on endocardial surfaces. Such insight may lead to new future treatment regimes for infective endocarditis.
Translating Obesity Prevention Research Into Practice: Targeting Infants At Risk
Funder
National Health and Medical Research Council
Funding Amount
$107,204.00
Summary
Childhood obesity is a significant public health concern, with one in four children aged 5 -14 years affected. Those from single parent and lower income families are at particular risk. Infancy and the preschool years are an ideal time for obesity prevention, before children have formed their lifelong eating habits. This project aims to design a program (informed by prior research) that is targeted toward those families most at risk, and that is community-based, practical and cost-effective.
From Advocacy To Action: Utilising Health Impact Assessment As A Tool To Realise The Right To Health.
Funder
National Health and Medical Research Council
Funding Amount
$97,419.00
Summary
The actions of governments often affect people’s health and wellbeing. Health Impact Assessment (HIA) is used to identify how these actions may impact on health and develop recommendations about how to maximise positive health benefits and reduce or stop negative impacts. This project is investigating how human rights can be used to strengthen the role of HIA in protecting the right to health.
Optimising Management Of Injection-related Infections In People Who Inject Drugs
Funder
National Health and Medical Research Council
Funding Amount
$132,743.00
Summary
People who inject drugs are a vulnerable group who are at increased risk of bacterial infections, which can lead to serious illness and death. This project aims to optimize management of bacterial infections in people who inject drugs. Measuring the current burden of infections, analysing different management strategies employed in hospitals and discussing attitudes and barriers to care with both healthcare workers and people who inject drugs will provide the evidence to optimize ongoing care.
Livelihoods Of Indigenous People Displaced From Remote Communities To Urban Centres For Dialysis Treatment
Funder
National Health and Medical Research Council
Funding Amount
$86,117.00
Summary
Kidney disease has a profound impact on Indigenous Australians due to outcomes of the disease itself and consequences of treatment. Indigenous people displaced from remote areas to urban centres for dialysis for kidney disease and their families are likely to have few assets or opportunities to generate livelihoods. This study combines public health and livelihoods-based approaches to understand the livelihoods of displaced people and analyse the policy and health and community service context.
Evidence-based Policy To End Rheumatic Heart Disease In Australia
Funder
National Health and Medical Research Council
Funding Amount
$128,224.00
Summary
Rheumatic heart disease (RHD) occurs when untreated infections from streptococcal bacteria cause heart valve damage. RHD is almost exclusively a disease of Aboriginal and Torres Strait Islander Australians. Researchers are working on an endgame for RHD which will provide a set of recommendations to end the disease. This PhD is to understand how to ensure those recommendations are implemented. The outcomes will also help to control other diseases which are more common in Indigenous Australians.
Establishing The Use Of Bacterial Genomics In Australia
Funder
National Health and Medical Research Council
Funding Amount
$157,669.00
Summary
We propose to establish a set of fully assembled reference genomes through new technologies and methods to analyse data from high throughput genome sequencing of important bacterial pathogens in Australia. We aim to demonstrate the capabilities of genome sequencing in clinical situations by comparing the genomes from clinical bacterial isolates to the established and annotated reference genomes.
Gender As A Determinant Of Health – Consolidating The Evidence Base. An Analysis Of Gender Equity And Health Outcomes In Lower Income Countries, With A Focus On Maternal And Neonatal Mortality
Funder
National Health and Medical Research Council
Funding Amount
$122,714.00
Summary
Gender has been cited as a powerful influence on the extent and distribution of adverse health outcomes, especially maternal and neonatal mortality. It has been suggested that global health and development targets cannot be reached without adequate attention to gender equity. A strong evidence base is vital if gender is to be meaningfully considered in the post-2015 agenda. This thesis aims to extend this evidence base.
Determinants Of Outcomes In SLE: Impact Of Models Of Care, Socioeconomic Factors And Biologic Variables In A Multiethnic Australian Population
Funder
National Health and Medical Research Council
Funding Amount
$134,124.00
Summary
Lupus is a chronic disease where the immune cells attack multiple systems in the body, which can lead to severe organ damage and even death. It is known that genes, socioeconomics and models of care all individually influence the outcomes in lupus. The exact contribution of each one is poorly understood, because they are studied in isolation. This project will take an integrated approach to investigating the factors that influence outcomes in lupus, looking for potentially addressable effects.