Development Of Potent And Selective Blockers Of Acid Sensing Ion Channels For The Treatment Of Pain
Funder
National Health and Medical Research Council
Funding Amount
$578,704.00
Summary
More than three million Australians suffer from chronic pain, and there are few effective drugs available for treating this condition. A 2007 Access Economics Report estimated the economic burden of chronic pain in Australia at $34.3 billion. Acid-sensing ion channels (ASICs) are a recently discovered family of proteins that play a key role in sensing pain. The goal of this project is to develop potent blockers of these channels that can be used to treat patients suffering from persistent pain.