Radiosensitisation Of Diffuse Intrinsic Pontine Gliomas By Modulating Glucose Metabolism
Funder
National Health and Medical Research Council
Funding Amount
$325,000.00
Summary
Diffuse intrinsic pontine glioma (DIPG) represents the most aggressive cancer of childhood with no effective treatment available and radiotherapy is the only form of treatment that offers a transient benefit. We have successfully grown the first DIPG cells in the laboratory and found a new approach to radiosensitise them by targeting glucose metabolism. We will build on these findings and develop this treatment strategy to make this novel therapy available to children with this deadly disease.