Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-th ....Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-thalassaemia, understanding the specific aHb-binding factor, AHSP is a goal of national significance. In the long term, manipulation of AHSP function through gene therapy may have a direct role in the treatment of thalassaemia.Read moreRead less
An investigation of the impacts of increased power supply to the national grid by wind generators on the Australian electricity industry. The aim of this project is to discover the most economical and effective way to accommodate large increases in wind power into the national grid and to understand the effects on the national electricity market. This is crucial to ensure stability of electricity supply and affordable prices in the transition towards a low carbon economy.
Rapid starting and unsteady operation of hydraulic turbines. The project will investigate the ability of hydraulic turbines to start rapidly with the turbine spinning in air which is more water efficient and has lower maintenance costs than other methods. The project will allow higher use of hydroelectricity and higher penetration of wind or other intermittent renewable energy generation into an electricity grid.
No load diesel application in remote power systems. No load diesel application in remote power systems. This project aims to investigate and optimise no-load diesel application within remote area renewable hybrid power systems. While hundreds of remote Australian communities rely on expensive diesel for power generation, this project intends to increase penetration of alternative renewable sources into remote and isolated power systems. Using dual thermodynamic and electrical modelling, this pro ....No load diesel application in remote power systems. No load diesel application in remote power systems. This project aims to investigate and optimise no-load diesel application within remote area renewable hybrid power systems. While hundreds of remote Australian communities rely on expensive diesel for power generation, this project intends to increase penetration of alternative renewable sources into remote and isolated power systems. Using dual thermodynamic and electrical modelling, this project will investigate low to no-load diesel threshold capability, reducing diesel consumption at minimal costs. The project is expected to return immediate benefits to remote mining, defence and tourism based communities, providing a pathway to reduced diesel usage and increased renewable penetration.Read moreRead less