The cell types of the blood, such as red and white blood cells, are produced in the bone marrow from a rare stem cell. The stem cell uses a handful of important master-regulatory genes that act in a hierarchy to promote the blood cell differentiation process. This research aims to understand how these master-regulators function in isolation and together in producing the white blood cells that are required for our immune response to microbes, vaccination and to prevent cancer.
I am an infectious diseases physician and basic scientist interested in the immunopathogenesis of HIV and hepatitis B virus. My work focuses on HIV viral reservoirs and immune reconstitution and the adaptive immune response to hepatitis B virus.
I am infectious disease physician undertaking research on natural history and therapeutic strategies in viral hepatitis, including acute hepatitis C, chronic hepatitis C and chronic hepatitis B. The hepatitis C therapeutic research has a particular focus
I am an immunologist-cell biologist investigating the regulation of human immune responses in health and disease. The overall goal of this work is to improve immunity in individuals with immunodeficiencies, or during vaccination, or to attenuate immune re
I am an immunologist determining the development and function of the dendritic cell system, including its role in autoimmunity and resistance to infection.
I am cellular immunologist determining the important host immune cell types and effector molecules that control tumour initiation, growth, and metastasis.