The Role Of Tau In Experimental Retinal And Optic Nerve Pathology: Relevance To Glaucoma
Funder
National Health and Medical Research Council
Funding Amount
$375,225.00
Summary
Aberrant processing of the axonal protein, tau, is believed to underlie key pathological events in Alzheimer's Disease (AD). Recent data have suggested a link between AD pathology and retinal neuron death in glaucoma. We have further evidence that changes in tau also occur in models of retinal damage. We thus aim to characterise the role of tau in retinal injury models and to relate these findings to glaucoma with a view to having a greater understanding of this disease process.