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The central nucleus of the amygdala and alcohol-seeking behaviour. Alcohol abuse and alcoholism is a significant problem in Australia (and throughout the world). However, pharmacological interventions remain limited due to our poor understanding of the neural networks underlying addictive processes. These experiments will explain how the positive rewarding and negative reinforcing aspects of alcohol are transduced within the brain. We believe that our research will facilitate the ability to trea ....The central nucleus of the amygdala and alcohol-seeking behaviour. Alcohol abuse and alcoholism is a significant problem in Australia (and throughout the world). However, pharmacological interventions remain limited due to our poor understanding of the neural networks underlying addictive processes. These experiments will explain how the positive rewarding and negative reinforcing aspects of alcohol are transduced within the brain. We believe that our research will facilitate the ability to treat alcoholism at a pharmacological level, enabling the continuation of abstinence or the prevention of relapse, while allowing other factors such as social support structure and coping skills to be developed for each individual, with flow-on social and economic benefits for society as a whole. Read moreRead less
Roadside saliva based testing for amphetamine-type stimulants in drivers: An evaluation of the relationship between positive drug tests and driving impairment after the consumption of methamphetamine and MDMA. Since the implementation of random saliva tests for illicit substances in Victoria, 1 in 48 drivers intercepted have tested positive to the presence of methamphetamine. Because amphetamines have been reported to increase road crash risk, this finding highlights a significant road traffic p ....Roadside saliva based testing for amphetamine-type stimulants in drivers: An evaluation of the relationship between positive drug tests and driving impairment after the consumption of methamphetamine and MDMA. Since the implementation of random saliva tests for illicit substances in Victoria, 1 in 48 drivers intercepted have tested positive to the presence of methamphetamine. Because amphetamines have been reported to increase road crash risk, this finding highlights a significant road traffic problem. The proposed research will provide information on the most accurate saliva drug test to detect the presence of methamphetamine and MDMA in drivers, and will also provide data on the appropriate amphetamine cut-off level that relates to driving impairment. Accurate drug detection measures will result in better detection of drivers impaired by amphetamines, and in turn deter drivers from driving after consuming amphetamines.
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