Rad50 Protects The Integrity Of The Genome To Minimise Disease Risk
Funder
National Health and Medical Research Council
Funding Amount
$524,222.00
Summary
Exposure to both endogenous products of metabolism as well as a variety of exogenous agents (UV, X-rays) increases the risk of cancer and other diseases. This project is designed to further investigate a novel defect in the Rad50 gene that predisposes to genetic instability and cancer. In short we have described for the first time a patient with a defect in the Rad50 gene. This information will assist in understanding our defence systems against oxidative stress to reduce the risk of disease.