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Psychological Adjustment Following Complex Trauma Among Children And Adolescents In Emergency Settings.
Funder
National Health and Medical Research Council
Funding Amount
$362,512.00
Summary
Children are among the most vulnerable in disaster settings, and yet little is known about the development of psychological distress following complex trauma. Research conducted at Harvard University and The University of Western Australia will investigate how daily stressors impact psychological distress and resilience among children affected by war and natural disaster. The findings will inform the development of evidence-based mental health interventions for refugee youth in Australia.
Defining The Role Of Genetic Variants In Systemic Lupus Erythematosus: Copy Number Variants And Epigenetic Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$338,625.00
Summary
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with increased risk of mortality, severely impacting the quality of life for those affected. A large number of genes have been implicated in SLE susceptibility, however we know little of the genetic mechanisms proceeding disease onset. This project uses state of the art technology to define the role of genetic variants in SLE susceptibility and identify their importance across patients of different ethnic backgrounds.
Evaluating Recently Introduced Prevention Strategies And Investigating Further Aetiologies Of Cerebral Palsy
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Cerebral palsy is an early brain injury that affects movement. Every year in Australia, this life long condition will be identified in another 600 infants. This Early Career Fellowship will train an Australian researcher to evaluate promising prevention strategies that could reduce the overall incidence of cerebral palsy for the first time. The researcher will also investigate other causes of cerebral palsy including birth defects that occur very early in pregnancy.
Novel Actions Of HDL Cholesterol: A Potential New Strategy For Treatment Of Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$74,973.00
Summary
There are currently in excess of 170 million patients diagnosed with type 2 diabetes worldwide. Recent studies have identified novel actions of HDL cholesterol in relation to glucose and fat metabolism which provide a rationale for therapeutic approaches to raise levels of circulating HDL to manage the metabolic syndrome and type 2 diabetes. This research will investigate HDL signaling pathways and contribute significantly to our understanding of the metabolic actions of HDL in Humans.
The first kernels of cardiovascular disease begin very early in life; in the womb and early infancy. These early indications are known to track into adulthood, eventually resulting in diseases such as heart attacks. Dr Huang has found that childhood obesity, high blood pressure, cholesterol and a "prediabetes" profile, cluster together and additionally are associated with many factors in the womb and first few years of life. She investigates how to give babies the optimal healthy start.
Identifying Social Pathways To Enhanced Life Outcomes In Aboriginal And Torres Strait Islander Children
Funder
National Health and Medical Research Council
Funding Amount
$316,449.00
Summary
This fellowship broadly aims to elucidate the social pathways to good and poor physical and mental health outcomes in Aboriginal and Torres Strait Islander children in Australia. This will identify the most salient social factors that drive ill health, disease and mortality, and improve population health strategies that aim to prevent poor health outcomes in early life. In doing so, I hope to support policies that can increase the pace of change toward health equity in Australia.