ARDC Research Link Australia

Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $679,744.00
Summary: This project will address the important question of the vascular risk of stroke associated with snoring and obstructive sleep apnoea, by using retinal photography of the eye to directly visualise the vascular changes in the cerebral circulation. Retinal photography may provide a useful clinical tool to help reduce the risk of stroke in patients with snoring and sleep apnoea.

Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $436,000.00
Summary: Cardiac problems account for many complications in patients undergoing major non-cardiac surgery, and even apparently minor cardiac damage is a marker of high risk for subsequent adverse events. Unfortunately, while money and effort is expended on identifying patients at risk, the appropriate response to this risk is quite unclear. The performance of bypass surgery or balloon angioplasty in order to treat the underlying coronary disease of at-risk patients is used in other situations, and reduce ....
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Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $317,308.00
Summary: A-Prof Wheatley is a respiratory and sleep disorders physician investigating the pathogenesis, health consequences and management of sleep breathing disorders, including sleep apnoea and snoring.

Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $697,512.00
Summary: Mild sleep disordered breathing, including habitual snoring, is a very common problem in the adult population, with a prevalence of between 20-40%. Increasingly it is now recognised that habitual snoring may be an independent risk factor for the development of stroke. In this proposal we will explore the hypothesis that treatment for snoring will slow or stop the development of carotid artery atherosclerosis.

Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $595,330.00
Summary: The balance between the ways that blood vessels decrease in size (constrict) and increase in size (dilate) determine how blood vessels normally function. There are many differences in the ways that blood vessels control this balance in different parts of the body. Such differences are altered in vascular diseases, such as hypertension and diabetes, which are prevalent in obesity, such that constriction generally outweighs dilation. However, what these differences are and how they occur are not w ....
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Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $593,833.00
Summary: Habitual snoring is a very common problem in the adult population, with a prevalence of between 20-40%. Increasingly it is now recognised that snoring may be an independent risk factor for the development of stroke. In this proposal, we will explore the hypothesis that chronic snoring transmits a pressure wave through the tissues of the neck to the carotid artery which may damage the artery wall and subsequently lead to stroke. This may lead to new strategies to treat habitual snoring.

Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $407,545.00
Summary: Human cytomegalovirus (HCMV) is a herpesvirus which infects a majority of the population. HCMV is a significant cause of serious, life-threatening disease in neonates and in people who are immunosuppressed. Transplant recipients such as bone marrow, kidney and heart transplant patients are particularly at risk of developing HCMV disease. Like other herpesviruses, after initial infection HCMV can establish a life-long latent infection. During latency, the virus remains dormant in the human body a ....
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Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $476,052.00
Summary: Snoring refers to a condition where the throat narrows significantly during sleep, and allows the soft tissues which surround this part of the airway to vibrate and create the typical snoring noise. Habitual snoring is a very common problem in the adult population, with a prevalence of between 20-40%. More severe forms of snoring are associated with the obstructive sleep apnoea syndrome, which is a condition in which the throat completely blocks behind the tongue and palate during sleep leading ....
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Funded Activity

Funder: National Health and Medical Research Council
Funding Amount: $149,250.00
Summary: Human cytomegalovirus (CMV) is a herpesvirus which infects a majority of the population. HCMV is a significant cause of serious, life-threatening disease in neonates and in people who are immunosuppressed. Transplant recipients such as bone marrow, kidney and heart transplant patients are particularly at risk of developing CMV disease. Like other herpesviruses, after initial infection CMV can establish a life-long latent infection. During latency, the virus remains dormant in the human body and ....
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