The Role Of Central Haemodynamics In Type 2 Diabetes Mellitus-related Brain Disease
Funder
National Health and Medical Research Council
Funding Amount
$899,704.00
Summary
Type 2 Diabetes Mellitus is associated with stiffening of major blood vessels which may allow the transmission of harmful pressure to the small vessels of the brain. This may in turn be responsible for damage to brain cells and a greater risk of dementia. This study will use state-of-the art techniques to test this theory. If true, it may open opportunities to reduce the risk of brain disease in diabetes by using therapies to reduce arterial stiffening.
ARC Centre of Excellence for Climate Extremes. This Centre aims to transform understanding of past and present climate extremes and revolutionise Australia’s capability to predict them into the future. Climate extremes cost Australia up to $4 billion a year and will intensify over coming decades. This Centre’s blue-sky research will discover processes that explain the behaviour of present and future climate extremes. It will use its researchers, data, modelling, collaboration, graduate programme ....ARC Centre of Excellence for Climate Extremes. This Centre aims to transform understanding of past and present climate extremes and revolutionise Australia’s capability to predict them into the future. Climate extremes cost Australia up to $4 billion a year and will intensify over coming decades. This Centre’s blue-sky research will discover processes that explain the behaviour of present and future climate extremes. It will use its researchers, data, modelling, collaboration, graduate programme and early career researcher mentoring to transform Australia’s capacity to predict climate extremes. This research is expected to make Australia more resilient to climate extremes and minimise risks from climate extremes to the Australian environment, society and economy.Read moreRead less
Southern Ocean aerosols: sources, sinks and impact on cloud properties. This project aims to provide fundamental process-level understanding of atmospheric aerosol processes over the Southern Ocean, a region that has a profound influence on the Australian and global climate and where climate models perform poorly. Comprehensive observations during 3 Southern Ocean voyages and land-based measurements will enhance our knowledge of aerosols and cloud formation in that region and provide much-needed ....Southern Ocean aerosols: sources, sinks and impact on cloud properties. This project aims to provide fundamental process-level understanding of atmospheric aerosol processes over the Southern Ocean, a region that has a profound influence on the Australian and global climate and where climate models perform poorly. Comprehensive observations during 3 Southern Ocean voyages and land-based measurements will enhance our knowledge of aerosols and cloud formation in that region and provide much-needed data for improving global climate models. Expected outcomes include more accurate seasonal and latitudinal representations of Southern Ocean aerosol populations, properties and sources. The main benefit includes improvements in weather forecasting and future climate projection for Australia and the Southern Hemisphere.Read moreRead less
Advanced micro analysis systems for environmental monitoring. Understanding of the behaviour of the nutrients controlling nuisance algae in water bodies is currently limited by the cost and logistics of collecting and analysing the large numbers of samples required.
This proposal describes the development and evaluation of portable multiparameter micro analysis systems that will be capable of high frequency measurements from a sampling vessel. This will enable environmental agencies to perfo ....Advanced micro analysis systems for environmental monitoring. Understanding of the behaviour of the nutrients controlling nuisance algae in water bodies is currently limited by the cost and logistics of collecting and analysing the large numbers of samples required.
This proposal describes the development and evaluation of portable multiparameter micro analysis systems that will be capable of high frequency measurements from a sampling vessel. This will enable environmental agencies to perform rapid on-site mapping of nutrients and other water quality parameters in large water bodies, intensive scale mapping of effluent mixing and dispersal zones, quick assessment of the impact of dredging and aquaculture, and compliance monitoring in effluent streams.
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Investigation into flow over complex topography and escarpments for wind turbine siting using experimental and computational methods. This project will improve national capability to optimise power production from wind turbine farms in complex terrain by improving the understanding of the flow regime. By better understanding separated regions and the turbulent structures within these regions power production can be optimised and fatigue risks associated with turbine positioning in complex sites ....Investigation into flow over complex topography and escarpments for wind turbine siting using experimental and computational methods. This project will improve national capability to optimise power production from wind turbine farms in complex terrain by improving the understanding of the flow regime. By better understanding separated regions and the turbulent structures within these regions power production can be optimised and fatigue risks associated with turbine positioning in complex sites can be reduced. This will improve confidence in wind farm site assessment techniques and consequently reduce economic risks associated with current wind farm viability assessments. By increasing national capacity to generate clean energy stationary energy emissions can be reduced. This project will also deliver high calibre graduates that will be potential future industry leaders.Read moreRead less
3D printed microchemical devices and systems. This project aims to address the barriers faced by 3D printing in chemistry. 3D printing can create bespoke 3D structures within a fraction of time and cost compared to traditional fabrication. However, its scope in chemistry has been limited by the poor chemical robustness, biotoxicity and low resolution of the 3D printed components. Hence, this project will develop novel gold coating techniques and explore high-resolution 3D printing to overcome th ....3D printed microchemical devices and systems. This project aims to address the barriers faced by 3D printing in chemistry. 3D printing can create bespoke 3D structures within a fraction of time and cost compared to traditional fabrication. However, its scope in chemistry has been limited by the poor chemical robustness, biotoxicity and low resolution of the 3D printed components. Hence, this project will develop novel gold coating techniques and explore high-resolution 3D printing to overcome these challenges. The project should generate commercially significant products (analytical platforms), technology (gold coating) and patents. The developed systems and technologies will address Australian research challenges in advanced manufacturing and enable on-site environmental monitoring.Read moreRead less
An autonomous microfluidic analyser for the determination of total phosphorus and nitrogen in aquatic systems. Development of automated monitoring systems capable of extended and remote operation will enable assessment of the effectiveness of water treatment and the impact of nutrient releases on the aquatic environment. Both are important in preserving the quality of existing water resources, and assessing the quality of recycled water, in line with the National Research Priority Environmentall ....An autonomous microfluidic analyser for the determination of total phosphorus and nitrogen in aquatic systems. Development of automated monitoring systems capable of extended and remote operation will enable assessment of the effectiveness of water treatment and the impact of nutrient releases on the aquatic environment. Both are important in preserving the quality of existing water resources, and assessing the quality of recycled water, in line with the National Research Priority Environmentally sustainable Australia, and the Priority Goal, Water - a critical resource. Commercialization of the microfluidic flow analysis system for total N and P will enhance the international competitiveness of Ecotech Pty Ltd and Australia as an exporter of scientific instruments.Read moreRead less
Precipitation in wintertime storms across southeast Australia, Tasmania and the Southern Ocean. The pristine conditions and strong wind-shear over the Southern Ocean affect the formation of precipitation in clouds over the region, which is vital to the water supply of southeastern Australia and Tasmania. This project will evaluate and improve the ability to simulate this precipitation, which will lead to better water resource management.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100094
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Development of a world-class facility for three dimensional dynamic testing. Development of a world-class facility for three dimensional dynamic testing: This project aims to establish a world-class facility for multi-directional dynamic testing. Currently there are no such facilities in Australia. The ability to recreate dynamic motion in all available degrees-of-freedom opens up enormous fields of research not currently possible in Australia. This includes such areas as vibration testing, mate ....Development of a world-class facility for three dimensional dynamic testing. Development of a world-class facility for three dimensional dynamic testing: This project aims to establish a world-class facility for multi-directional dynamic testing. Currently there are no such facilities in Australia. The ability to recreate dynamic motion in all available degrees-of-freedom opens up enormous fields of research not currently possible in Australia. This includes such areas as vibration testing, materials testing, biomechanics and human factors, blast and earthquake simulations, field robotics, automotive safety research, flight/vehicle simulation, and marine applications including sloshing of liquids and liquefaction of fines. In conjunction with a 3D laser doppler system this facility will be unique in the world for dynamic mechanical testing.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140100076
Funder
Australian Research Council
Funding Amount
$394,585.00
Summary
Mixing hot spots in the Southern Ocean: processes, parameterisations and climate impacts. The Southern Ocean plays a critical role in the uptake of heat and carbon dioxide from the atmosphere into the deep ocean. This uptake depends strongly on mixing processes due to ocean eddies, which are especially important in regions of steep topography, leading to localised mixing hot spots. These ocean eddies have scales of 10-100km and therefore can not be resolved in current global climate models. This ....Mixing hot spots in the Southern Ocean: processes, parameterisations and climate impacts. The Southern Ocean plays a critical role in the uptake of heat and carbon dioxide from the atmosphere into the deep ocean. This uptake depends strongly on mixing processes due to ocean eddies, which are especially important in regions of steep topography, leading to localised mixing hot spots. These ocean eddies have scales of 10-100km and therefore can not be resolved in current global climate models. This project will examine these mixing processes using a combination of observations and innovative modelling approaches. This knowledge will be used to improve the representation of eddy processes in state-of-the-art climate models, which will ultimately allow Australia to more effectively respond to the challenge of climate change.Read moreRead less