Saving energy on trains - demonstration, evaluation, integration. Reducing energy use from rail transport will significantly contribute to cutting carbon dioxide emissions. This project will develop a toolkit to facilitate the introduction of in-cab technologies that help train drivers save energy and stay on time. The toolkit will make it easier to demonstrate, evaluate and integrate the system in a range of railways.
Faster, cheaper, better: mathematical advances for improved design and scheduling of robotic instrumentation. This project extends previous research addressing mathematical challenges in the optimal design and scheduling of robotic instrumentation. The Partner Organisation manufactures instruments for cancer diagnostics, and designs instruments that need to produce rapid, high-quality results, at a reasonable cost in a competitive market. It is intended that powerful new scheduling algorithms wi ....Faster, cheaper, better: mathematical advances for improved design and scheduling of robotic instrumentation. This project extends previous research addressing mathematical challenges in the optimal design and scheduling of robotic instrumentation. The Partner Organisation manufactures instruments for cancer diagnostics, and designs instruments that need to produce rapid, high-quality results, at a reasonable cost in a competitive market. It is intended that powerful new scheduling algorithms will be devised to handle their complex problem, which is more challenging than standard problems. The developed methodologies aim to reduce the product development cycle and boost the competitiveness of Australian manufacturers. In addition, new theoretical and algorithmic contributions aim to enable improved scheduling in other application areas.Read moreRead less
Innovative mathematical modelling to determine incorporation of gene therapy in different cell lineages; Human Immunodeficiency Virus (HIV) as a model setting. Gene therapy is a promising therapeutic that is being developed to address genetic diseases and viral infections such as Human Immunodeficiency Virus (HIV). This project will produce mathematical models of how gene therapy delivered to one type of cell can differentiate into the desired end target and impact disease.
Development of a Risk Assessment and Cost-Effectiveness Model for Optimising Geotechnical Roadway Assets. Roadway performance is strongly a function of the topography and foundation conditions through which the roadway passes, dictating the need for cuttings and fills, and approaches to handle problematic foundation conditions. The project aims to develop a risk management model to minimise the geotechnical risks and costs involved in roadway construction and maintenance, and maximise design li ....Development of a Risk Assessment and Cost-Effectiveness Model for Optimising Geotechnical Roadway Assets. Roadway performance is strongly a function of the topography and foundation conditions through which the roadway passes, dictating the need for cuttings and fills, and approaches to handle problematic foundation conditions. The project aims to develop a risk management model to minimise the geotechnical risks and costs involved in roadway construction and maintenance, and maximise design life. In Queensland, the value of roadway geotechnical assets is about $ 7.5 billion, with $ 0.5 billion spent annually adding to and maintaining these assets. The expected outcome of the project is maximising the life of geotechnical roadway assets for the funds available.Read moreRead less
Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV? Approximately 15,000 individuals in Australia are currently HIV infected. Gene therapy has the capacity to remove antiretroviral treatment related issues, dramatically decrease treatment costs and simplify treatment of HIV.
In this study we will model a new approach to treat HIV in which the patient's own cells are used as the therapy by incorporating an anti-HIV gene. These cells are then re-introduced into the p ....Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV? Approximately 15,000 individuals in Australia are currently HIV infected. Gene therapy has the capacity to remove antiretroviral treatment related issues, dramatically decrease treatment costs and simplify treatment of HIV.
In this study we will model a new approach to treat HIV in which the patient's own cells are used as the therapy by incorporating an anti-HIV gene. These cells are then re-introduced into the patient.
The strong mathematical focus of this project, and its application to a promising approach against HIV, will place Australia at the forefront of the mathematics of gene research and contribute to the National Priority Area of Promoting and Maintaining Good Health and the Priority Goal of Preventative Healthcare.
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An integrated mathematical approach to synchronise and optimise hospital operations. This project aims to develop an integrated mathematical approach to synchronise and optimise patient scheduling systems of different departments to ensure that the hospital’s assets and related resources are used efficiently. The project’s aim is to investigate patient flow, process delay, and the interaction and inter-dependence of departments within the hospital to reduce access block (bottleneck) and subseque ....An integrated mathematical approach to synchronise and optimise hospital operations. This project aims to develop an integrated mathematical approach to synchronise and optimise patient scheduling systems of different departments to ensure that the hospital’s assets and related resources are used efficiently. The project’s aim is to investigate patient flow, process delay, and the interaction and inter-dependence of departments within the hospital to reduce access block (bottleneck) and subsequent overcrowding. This project aims to smooth the running of the hospital, improve the efficiency of patient throughput, reduce waiting times, and revolutionise hospital planning and scheduling.Read moreRead less
Optimisation of Rail Network Infrastructure Capacity under Dynamic Train Planning. Recent changes in railway operating environments have caused significant operational and management problems in Australia. This research will lead to improvements of railway's key managerial functions, namely: network capacity planning; rollingstock planning; train scheduling; and maintenance planning. The major outcome of the research will be to develop an optimisation model to significantly improve the operati ....Optimisation of Rail Network Infrastructure Capacity under Dynamic Train Planning. Recent changes in railway operating environments have caused significant operational and management problems in Australia. This research will lead to improvements of railway's key managerial functions, namely: network capacity planning; rollingstock planning; train scheduling; and maintenance planning. The major outcome of the research will be to develop an optimisation model to significantly improve the operating efficiency and assets productivity of Australia's rail system. The novelty of the research is that it will be undertaken using innovations based on modern job shop scheduling and sequencing optimisation techniques as the complexity of the problem makes it impossible to solve by classic optimisation techniques.Read moreRead less
Managing Australia's water resources: Automated demand scheduling and supply control systems for large scale irrigation networks. Irrigation water delivery losses in Australia are equal in volume to the total non-agricultural water consumption nationwide. In a drought-prone country where water is such a scarce resource, precise water management is critical. Through the intelligent development and application of technology to the supply and management of water flows in irrigation networks, this p ....Managing Australia's water resources: Automated demand scheduling and supply control systems for large scale irrigation networks. Irrigation water delivery losses in Australia are equal in volume to the total non-agricultural water consumption nationwide. In a drought-prone country where water is such a scarce resource, precise water management is critical. Through the intelligent development and application of technology to the supply and management of water flows in irrigation networks, this project will deliver increased flexibility and security in water delivery to farmers, and substantial water savings overall. These benefits will lead directly to increased productivity and growth in the rural sector and wider economy, whilst providing improved environmental and catchment flows of benefit to all Australians.Read moreRead less
Synchromodal container logistics for Australia. Synchromodal container logistics for Australia. This project aims to develop advanced mathematical optimization models and algorithms to create multi-modal logistics approaches for container movements in and out of Australia’s busy ports. The increasingly congested capital cities of Sydney, Brisbane and Melbourne need to find new ways of moving an increasing volume of containerized freight. Moving from trucks to rail is expected to reduce pollution ....Synchromodal container logistics for Australia. Synchromodal container logistics for Australia. This project aims to develop advanced mathematical optimization models and algorithms to create multi-modal logistics approaches for container movements in and out of Australia’s busy ports. The increasingly congested capital cities of Sydney, Brisbane and Melbourne need to find new ways of moving an increasing volume of containerized freight. Moving from trucks to rail is expected to reduce pollution and road congestion, but is only possible if highly efficient modes of operation can be developed. Research into system design and operational scheduling is expected to achieve the required efficiency for multi-modal logistics that will reduce air pollution and road congestion.Read moreRead less
Hybrid Job Shop Techniques for Dynamic Train Scheduling. The job shop approach to dynamic train scheduling promises considerable benefits over existing approaches, and allows problems of large size and complexity to be solved with great accuracy. The application of research results in Australia has the potential to:
- reduce train delays and costs by better planning of train schedules of railway systems;
- reduce transport costs to rail customers and increase rail's market share of freight ....Hybrid Job Shop Techniques for Dynamic Train Scheduling. The job shop approach to dynamic train scheduling promises considerable benefits over existing approaches, and allows problems of large size and complexity to be solved with great accuracy. The application of research results in Australia has the potential to:
- reduce train delays and costs by better planning of train schedules of railway systems;
- reduce transport costs to rail customers and increase rail's market share of freight movements;
- enhance the ability of operators to control operations in an efficient manner and minimise conflicts;
- to increase efficiency of Australian Railway System, leading to lower operating and capital costs;
- optimise the energy consumed.
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