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Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and ....Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and a better understanding of long-run health and inequality. These should provide economic and social benefits by informing policy aimed at contemporary social and health challenges, enhancing our understanding of Australian history, and developing public resources.Read moreRead less
Transforming The Diagnosis And Management Of Severe Neurocognitive Disorders Through Genomics
Funder
National Health and Medical Research Council
Funding Amount
$2,499,330.00
Summary
Neurocognitive disorders (NCD) are one of the most common genetic conditions in our society and it results with a need for ongoing permanent care for many affected people. Until recently, only 30% of people with NCD could be diagnosed but this has changed with the availability of genomic testing where all genes can be tested at once. The use of genomics in the CRE will lead to new NCD genes being identified and this information being translated into a clinical setting.
Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
Preventing Hospital Readmission In A Regional Australian Hospital Setting
Funder
National Health and Medical Research Council
Funding Amount
$565,695.00
Summary
Hospitals face high levels of emergency presentations and demand for inpatient care particularly for Aboriginal Australian people from remote communities. Readmissions lead to overcrowded emergency departments and poorer patient outcomes. We will evaluate the efficacy of a multidimensional case-based management intervention linking hospital and primary health in a regional Australian hospital with the aim of reducing hospital readmission and improving patient outcomes.
Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of ....A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of these shock waves, while simultaneously unifying existing regularisation techniques under a single, geometric banner. It will devise innovative tools in singular perturbation theory and stability analysis that will identify key parameters in the creation of shock waves, as well as their dynamic behaviour.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775716
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Infrastructure for a Spatially Integrated Social Science e-Research Facility. The requested facility with its Nationally Distributed Socio-Spatial Data System and On-Line Analysis, Modeling and Visualisation Research Facility will enhance Australia's national research capacity for secondary data analysis and modeling of socio-spatial information with visualisation, substantially reducing the cost of innovative research conducted at various levels of spatial scale to investigate both local and na ....Infrastructure for a Spatially Integrated Social Science e-Research Facility. The requested facility with its Nationally Distributed Socio-Spatial Data System and On-Line Analysis, Modeling and Visualisation Research Facility will enhance Australia's national research capacity for secondary data analysis and modeling of socio-spatial information with visualisation, substantially reducing the cost of innovative research conducted at various levels of spatial scale to investigate both local and nationally significant demographic, social, economic and behavioural issues. It will deliver national/community benefits through enabling hundreds of researchers and graduate students across the university system to investigate demographic, economic and social issues at various levels of spatial scale.Read moreRead less
Identifying cost-effective reforestation approaches for biodiversity conservation and carbon sequestration in the Australian wet tropics. There is great potential for rainforest reforestation to help in the protection of Australia's tropical flora and fauna. Little is known, however, about how to reforest pasture to rainforest for the purpose of maximising the recovery of native biodiversity. We propose a unique experimental study of rainforest reforestation practices with biodiversity conservat ....Identifying cost-effective reforestation approaches for biodiversity conservation and carbon sequestration in the Australian wet tropics. There is great potential for rainforest reforestation to help in the protection of Australia's tropical flora and fauna. Little is known, however, about how to reforest pasture to rainforest for the purpose of maximising the recovery of native biodiversity. We propose a unique experimental study of rainforest reforestation practices with biodiversity conservation as a primary goal. Reforestation is currently an unlikely option for most landholders in Australia's tropics given the lack of data on the economic benefits obtainable from such efforts. Our study examines the profits obtainable through the carbon market for each reforestation approach with the goal of increasing the feasibility of rainforest reforestation in North Queensland.Read moreRead less
A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic ev ....A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic evaluation, improving the quality of life and wellbeing of older Australians, and will assist in determining the relative cost effectiveness of new and existing services.
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A health economic model for the development and evaluation of innovations in aged care: an application to consumer directed care. This project will investigate the preferences, quality of life outcomes and cost effectiveness of a new consumer directed care approach to community aged care service delivery for older people. The applicability of a health economic model in the development and economic evaluation of innovations in aged care service delivery will be demonstrated.