Rethinking the Data-driven Discovery of Rare Phenomena. This project will investigate novel technologies for the data-driven discovery of rare phenomena. Scientific disciplines are increasingly able to generate large amounts of data relevant to key discoveries such as novel photovoltaic materials or explanations of brain seizures. However, these discoveries typically correspond to extremely rare phenomena in high dimensional spaces, which current data science methods are unable to detect. The pr ....Rethinking the Data-driven Discovery of Rare Phenomena. This project will investigate novel technologies for the data-driven discovery of rare phenomena. Scientific disciplines are increasingly able to generate large amounts of data relevant to key discoveries such as novel photovoltaic materials or explanations of brain seizures. However, these discoveries typically correspond to extremely rare phenomena in high dimensional spaces, which current data science methods are unable to detect. The project will fill this void and yield novel methods, publications, and open source software for the data-driven discovery or rare phenomena. Thus, it will expand the capabilities of data science, providing better use of the massive data collections accumulating across science, government, and industry.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100200
Funder
Australian Research Council
Funding Amount
$418,398.00
Summary
Next generation causal inference methods for biological data. This project aims to develop next generation causal inference methods for analysing biological data especially the single cell sequencing data and their applications in cell biology. Although Artificial Intelligence and Statistical Machine Learning have been applied successfully in many fields, including biological research, there is still a serious lack of methods for interpreting and reasoning about the mechanism of biological syste ....Next generation causal inference methods for biological data. This project aims to develop next generation causal inference methods for analysing biological data especially the single cell sequencing data and their applications in cell biology. Although Artificial Intelligence and Statistical Machine Learning have been applied successfully in many fields, including biological research, there is still a serious lack of methods for interpreting and reasoning about the mechanism of biological systems, the ultimate goal of research in many areas. Efficient data-driven causality discovery approaches developed by the project will be a timely and significant contribution to the knowledge of biology and statistics as well as the battle against health threats.
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Mathematical modelling of information flow in social networks. This proposal aims to develop new mathematical and statistical methods to understand information flow in social networks. By using novel information theoretic techniques, it will create new methods to characterise social information flow in social networks. These tools will allow derivation of fundamental limits of predictability for AI methods applied to digital data. New mathematics of information flow will produce insights into so ....Mathematical modelling of information flow in social networks. This proposal aims to develop new mathematical and statistical methods to understand information flow in social networks. By using novel information theoretic techniques, it will create new methods to characterise social information flow in social networks. These tools will allow derivation of fundamental limits of predictability for AI methods applied to digital data. New mathematics of information flow will produce insights into social influence in online social networks. Benefits include: better understanding of how echo chambers may form in social networks, predictive models for how misinformation can spread online such as during an emergency, and a framework for intercomparison of AI methods applied to digital data on individuals. Read moreRead less
Advances in data integration modelling for infectious disease response. This project aims to develop powerful mathematical frameworks that integrate data from multiple sources to facilitate informed decisions in response to the threat of present, and future, infectious diseases. The project expects to generate new knowledge in mathematics by advancing the tools for incorporating multiple data sources into models of infectious diseases. The expected outcomes include enhanced capacity to predict s ....Advances in data integration modelling for infectious disease response. This project aims to develop powerful mathematical frameworks that integrate data from multiple sources to facilitate informed decisions in response to the threat of present, and future, infectious diseases. The project expects to generate new knowledge in mathematics by advancing the tools for incorporating multiple data sources into models of infectious diseases. The expected outcomes include enhanced capacity to predict spatiotemporal changes in transmission of infectious diseases. This project should provide significant benefits in the advancement of modelling techniques broadly applicable to infectious disease settings, which will be demonstrated for antimalarial drug resistance – a major threat to malaria elimination.
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Scalable and Robust Bayesian Inference for Implicit Statistical Models. This project aims to develop the next generation of efficient methods for fitting complex simulation-based statistical models to data. Practitioners and scientists are interested in such implicit models to enable discoveries, produce accurate predictions and inform decisions under uncertainty. However, the associated computational cost has restricted researchers to implicit models that must have a small number of parameters ....Scalable and Robust Bayesian Inference for Implicit Statistical Models. This project aims to develop the next generation of efficient methods for fitting complex simulation-based statistical models to data. Practitioners and scientists are interested in such implicit models to enable discoveries, produce accurate predictions and inform decisions under uncertainty. However, the associated computational cost has restricted researchers to implicit models that must have a small number of parameters and be well specified, impeding scientific progress. This project will develop new computational methods and algorithms for implicit models that scale to high dimensions and are robust to misspecification. Benefits will arise from the more routine use of implicit models in epidemiology, biology, ecology and other fields.Read moreRead less
Advances in Sequential Monte Carlo Methods for Complex Bayesian Models. This project aims to develop efficient statistical algorithms for parameter estimation of complex stochastic models that currently cannot be handled. Parameter estimation is an essential component of mathematical modelling for answering scientific questions and revealing new insights. Current parameter estimation methods can be inefficient and require too much user intervention. This project will develop novel Bayesian alg ....Advances in Sequential Monte Carlo Methods for Complex Bayesian Models. This project aims to develop efficient statistical algorithms for parameter estimation of complex stochastic models that currently cannot be handled. Parameter estimation is an essential component of mathematical modelling for answering scientific questions and revealing new insights. Current parameter estimation methods can be inefficient and require too much user intervention. This project will develop novel Bayesian algorithms that are optimally automated and efficient by exploiting ever-improving parallel computing devices. The new methods will allow practitioners to process realistic models, enabling new scientific discoveries in a wide range of disciplines such as biology, ecology, agriculture, hydrology and finance.Read moreRead less
Optimising progress towards elimination of malaria. The project aims to advance mathematical knowledge by developing novel tools appropriate for modelling disease elimination. We will apply these new mathematical tools to the significant problem of malaria elimination in Vietnam. The expected outcomes are new tools for modelling disease elimination on a fine spatial resolution with heterogeneities in individual patient characteristics, calibrating models to household level data on disease transm ....Optimising progress towards elimination of malaria. The project aims to advance mathematical knowledge by developing novel tools appropriate for modelling disease elimination. We will apply these new mathematical tools to the significant problem of malaria elimination in Vietnam. The expected outcomes are new tools for modelling disease elimination on a fine spatial resolution with heterogeneities in individual patient characteristics, calibrating models to household level data on disease transmission and designing intervention strategies for maximum effect on disease transmission. The innovative combination of modelling, inference and optimisation ensures that the mathematical methods developed will be broadly applicable to modelling elimination strategies for other infectious diseases.
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Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable mode ....Statistical methods for quantifying variation in spatiotemporal areal data. This project aims to develop new statistical methods for extracting insights into spatial and temporal variation in areal data. These tools will extend the Australian Cancer Atlas which provides small area estimates for 20 cancers across Australia. The project is significant because it will allow government and other organisations to reap dividends from investment in collecting spatial information and it will enable modelled small-area estimates to be released without compromising confidentiality. The expected outcomes include new statistical knowledge and new insights into cancer. The results will benefit the many disciplines, managers and policy makers that make decisions based on geographic data mapped over space and time. Read moreRead less
Remote sensing to improve structural efficiency of high-speed catamarans. This project aims to develop a monitoring system to remotely measure ship motions, loads and ride control activity under commercial operations. Data will be analysed using advanced statistical methods to inform evidence-based design to improve both structural efficiency and passenger comfort. The research will impact on design rules used worldwide, reducing weight and increasing payload and transport efficiency for this cl ....Remote sensing to improve structural efficiency of high-speed catamarans. This project aims to develop a monitoring system to remotely measure ship motions, loads and ride control activity under commercial operations. Data will be analysed using advanced statistical methods to inform evidence-based design to improve both structural efficiency and passenger comfort. The research will impact on design rules used worldwide, reducing weight and increasing payload and transport efficiency for this class of vessel. A "Smart” semi-autonomous interface will be developed to provide on-board seakeeping guidance to the ship captain. This technology will have significant benefits such as increased ship safety, vessel longevity and improving passenger comfort for all types of vessels worldwide including high-speed catamarans.Read moreRead less
In for the count: Maximising trust and reliability in Australian elections. This project aims to develop innovative approaches to identifying, measuring, and evaluating errors and purposeful intervention in the uniquely complex elections at the basis of Australian democracy. Such methods can underpin a world-class election auditing system, which contends with the risks that are emerging at the intersection of election digitisation, cybersecurity and foreign interference. The project’s expected o ....In for the count: Maximising trust and reliability in Australian elections. This project aims to develop innovative approaches to identifying, measuring, and evaluating errors and purposeful intervention in the uniquely complex elections at the basis of Australian democracy. Such methods can underpin a world-class election auditing system, which contends with the risks that are emerging at the intersection of election digitisation, cybersecurity and foreign interference. The project’s expected outcomes are new auditing methods, tested on real Australian election data, with their benefits quantified against global best practice. The research outputs should help reinforce the community’s trust in Australian elections, which are a foundation for our security, social cohesion, and political resilience.Read moreRead less