A more intelligent knowledge-based system apprentice. Our previous techniques already had an impact on Australian industry, with five Australian companies marketing such technology, and for three of these it is a central technology. We expect an early uptake of the enhancements we propose by these companies, greatly increasing their international competitiveness against other rule technologies. Three of these companies are very recent, so we would expect other company uptake of the new enhance ....A more intelligent knowledge-based system apprentice. Our previous techniques already had an impact on Australian industry, with five Australian companies marketing such technology, and for three of these it is a central technology. We expect an early uptake of the enhancements we propose by these companies, greatly increasing their international competitiveness against other rule technologies. Three of these companies are very recent, so we would expect other company uptake of the new enhanced technology. In turn Australian companies using the technology will improve their competitiveness in an increasingly knowledge-based economy by being able to more rapidly and easily deploy knowledge-based systems. Our previous techniques have already had a significant impact in medical practice.Read moreRead less
Social acceptability of forest management options: Landscape level visualisation and evaluation. Sustainable forest policy requires social acceptance. Prior research has investigated relative acceptability of options at a forest stand level. However, we have insufficient understanding of public acceptance of forest management systems implemented across the wider landscape. Only detailed knowledge of public reaction to social, environmental and economic impacts and the trade-offs involved can red ....Social acceptability of forest management options: Landscape level visualisation and evaluation. Sustainable forest policy requires social acceptance. Prior research has investigated relative acceptability of options at a forest stand level. However, we have insufficient understanding of public acceptance of forest management systems implemented across the wider landscape. Only detailed knowledge of public reaction to social, environmental and economic impacts and the trade-offs involved can reduce the divisive nature of the forest management debate. This project will use interactive, still and animated computer representations of landscapes to examine social acceptability of alternatives to clearfell harvesting. This knowledge will be integrated with biophysical data to improve management of forested landscapes.Read moreRead less
Acceptability of Forest Harvesting Systems. Fierce public debate over forest management has prompted forest agencies to develop and test alternative harvesting systems. This project will examine community response to these harvesting and regeneration options. It will avoid the biases of existing research by developing an interactive simulation of the forest environment that will allow participants to view visual, ecological and economic outcomes of harvest options, as well as changes over time ....Acceptability of Forest Harvesting Systems. Fierce public debate over forest management has prompted forest agencies to develop and test alternative harvesting systems. This project will examine community response to these harvesting and regeneration options. It will avoid the biases of existing research by developing an interactive simulation of the forest environment that will allow participants to view visual, ecological and economic outcomes of harvest options, as well as changes over time as forest regenerates. Public judgements of the acceptability of harvesting options will be integrated with the outcomes of related biophysical studies to identify socially and ecologically sustainable management options for Australian native forests.Read moreRead less
ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environme ....ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environments. EII will address 3 tightly coupled research themes: Ability to interoperate across existing heterogenous platforms & applications; Efficient processing of very large data sets; Technology adoption & impact. Generic results will be applicable to e-science and large business information systems installations.Read moreRead less
Uncovering the genetic basis for saxitoxin production in Australian marine and freshwater systems: novel molecular tools for management. In Australia, toxic algal blooms have had a devastating impact on marine and freshwater resources. In collaboration with a biotechnology company, this project will use an innovative method to design a molecular genetic tool to monitor, research and potentially mitigate the effects of saxitoxin production on water supplies and aquaculture industries. In working ....Uncovering the genetic basis for saxitoxin production in Australian marine and freshwater systems: novel molecular tools for management. In Australia, toxic algal blooms have had a devastating impact on marine and freshwater resources. In collaboration with a biotechnology company, this project will use an innovative method to design a molecular genetic tool to monitor, research and potentially mitigate the effects of saxitoxin production on water supplies and aquaculture industries. In working with monitoring authorities throughout Australia, we will produce a specific, sensitive and cost-effective technology that will ultimately be applicable worldwide. Read moreRead less
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
A Roadmap for Greening Existing Australian Housing. The project will minimise the impact of the Greenhouse Pollution Reduction Scheme and anticipated rises in water costs on the householders. It will assist the consumers and the building industry in evaluating the environmental and economic costs and benefits of specific retrofitting actions for building envelope and major fixed appliances (thermal insulation, glazing, air infiltration, hot water, heating/cooling, lighting, low water flow and wa ....A Roadmap for Greening Existing Australian Housing. The project will minimise the impact of the Greenhouse Pollution Reduction Scheme and anticipated rises in water costs on the householders. It will assist the consumers and the building industry in evaluating the environmental and economic costs and benefits of specific retrofitting actions for building envelope and major fixed appliances (thermal insulation, glazing, air infiltration, hot water, heating/cooling, lighting, low water flow and water reuse appliances, and solar photovoltaic systems). In addition to assisting a burgeoning renovation industry, the project will enable accurate assessment of the impacts of the Green Loans Program and guide future national and local energy and water reduction policies. Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Identifying the specific structural features of metallothionein that regulate its ability to modulate astrogliosis. This project contributes directly to the Designated National Research Priority 2 and could potentially have a significant impact upon the broader Australian Community by identifying a novel and powerful therapeutic agent based upon metallothionein proteins with the ultimate aim of helping patients who have a brain injury or a neurodegenerative disease. It is important to note that ....Identifying the specific structural features of metallothionein that regulate its ability to modulate astrogliosis. This project contributes directly to the Designated National Research Priority 2 and could potentially have a significant impact upon the broader Australian Community by identifying a novel and powerful therapeutic agent based upon metallothionein proteins with the ultimate aim of helping patients who have a brain injury or a neurodegenerative disease. It is important to note that the partnership between UTAS and Bestenbalt LLC is a critical step in the development of these exciting research discoveries into commercially viable outcomes for the Australian Biotechnology Industry and the broader Australian community.Read moreRead less
Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These a ....Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These are significant community issues in both economical and social terms. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest cellular processes associated with aging or disease of the brain, and will provide clues to promoting healthy aging.Read moreRead less