The Effect Of Obstructive Sleep Apnoea And Its Treatment On Exercise Capacity On Obese Children
Funder
National Health and Medical Research Council
Funding Amount
$60,787.00
Summary
The aim of the study is to explore the effect of sleep apnoea and its treatment on obese children aged between 7 - 13 years. The project will study the effect of sleep apnoea and its recommended treatment on: 1. lung and cardiovascular function 2. blood markers (including cholesterol and insulin), and 3. quality of life in obese children. It is hoped this study will show treatment reverses any negative outcomes caused by sleep apnoea in obese children.
Obstructive Sleep Apnoea As A Risk Factor For Atrial Fibrillation
Funder
National Health and Medical Research Council
Funding Amount
$64,631.00
Summary
Atrial fibrillation is the most common sustained cardiac arrhythmia and obstructive sleep apnoea is a common sleep-related breathing disorder. It has recently been suggested that OSA increases the risk of developing AF . The aim, therefore of this study, is to determine the incidence of sleep apnoea in our population of highly symtomatic patients with atrial fibrillation and to assess the outcome on arrhythmia burden of treatment with continuous positive airways pressure (CPAP).
The Role Of Oxygen Therapy As Second-line Treatment For Patients With Obstructive Sleep Apnoea Who Are Intolerant Of Continuous Positive Airway Pressure Therapy, And Characterising Ventilatory Loop Gain As A Predictor Of The Success Of Therapy.
Funder
National Health and Medical Research Council
Funding Amount
$87,198.00
Summary
Obstructive sleep apnoea (OSA) is an increasingly common condition in Australia. Continuous positive airway pressure (CPAP) therapy is the _gold-standard� in OSA treatment, but a majority of sufferers are unable to tolerate this for the period required to treat their condition. We will be conducting a large Australian multi-centre, randomised, placebo controlled trial to investigate the utility of nocturnal oxygen therapy alone, in those people with OSA who are unable to tolerate CPAP.
Cardiometabolic Changes After Continuous Positive Airway Pressure Treatment For Obstructive Sleep Apnea
Funder
National Health and Medical Research Council
Funding Amount
$82,421.00
Summary
CPAP is the preferred treatment for patients with OSA because of its well-proven ability to decrease sleepiness and improve blood pressure control. This study will definitively establish if CPAP can also improve markers of cardio-metabolic health, such as visceral fat, insulin sensitivity, central blood pressure and arterial stiffness. The results of the study will shed light on the broader health consequences of OSA and contributes to the development of more targeted treatment strategies.