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A Randomised Trial Examining The Effectiveness Of Sympathetic Nervous Inhibition In Alleviating The Metabolic Side Effects Of Antipsychotic Medications In Patients With Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$477,426.00
Summary
Despite improved diagnosis and increased use of antipsychotic medications the mortality risk in patients with schizophrenia remains 2-3 times that of the general population, largely due to cardiovascular disease development. In this project we will test the effectiveness of sympathetic nervous inhibition with moxonidine (as add on therapy) in alleviating the metabolic side effects of antipsychotic medications in patients with schizophrenia.
Polypharmacy In The Heart Failure Patient: Are All Prescribed Drug Classes Required?
Funder
National Health and Medical Research Council
Funding Amount
$134,110.00
Summary
This project investigates the issue of polypharmacy is heart failure. Polypharmacy is the use of four or more prescription medications, and heart failure patients take six on average. This project investigates the evidence for safe withdrawal of medications failure that have not been shown to prolong life in heart, doctor and patient attitudes to withdrawing medications, and then runs a series of three clinical trials, each withdrawing a different medication in heart failure patients and closely ....This project investigates the issue of polypharmacy is heart failure. Polypharmacy is the use of four or more prescription medications, and heart failure patients take six on average. This project investigates the evidence for safe withdrawal of medications failure that have not been shown to prolong life in heart, doctor and patient attitudes to withdrawing medications, and then runs a series of three clinical trials, each withdrawing a different medication in heart failure patients and closely monitors the effects.Read moreRead less