Is Calcium part of the mechanism used in glucose signalling in embryogenesis. A vital stage in the development of the embryo is formation of the blastocyst about 4 days after conception. For this to happen the embryo must receive glucose from the mother. We believe that rather being used by the embryo to generate energy, this glucose acts as a signal to switch on the developmental pathway leading to blastocyst formation. Without this signal there is no blastocyst and the pregnancy fails. The pr ....Is Calcium part of the mechanism used in glucose signalling in embryogenesis. A vital stage in the development of the embryo is formation of the blastocyst about 4 days after conception. For this to happen the embryo must receive glucose from the mother. We believe that rather being used by the embryo to generate energy, this glucose acts as a signal to switch on the developmental pathway leading to blastocyst formation. Without this signal there is no blastocyst and the pregnancy fails. The project investigates this signal mechanism. The results will advance understanding of the mechanisms regulating development and in particular link the mother's nutritive status to her fertility during very early pregnancy.Read moreRead less
Evolution of the biofabrication of mineralized structures in animals. Shells and skeletons are produced by a wide range of animals. These highly-order crystalline structures are genetically-encoded and produce high-performance composite materials that exceed present capabilities in human engineering. This international collaboration will elucidate the molecular mechanisms controlling the fabrication of these architectures. This knowledge will contribute significantly to the development of materi ....Evolution of the biofabrication of mineralized structures in animals. Shells and skeletons are produced by a wide range of animals. These highly-order crystalline structures are genetically-encoded and produce high-performance composite materials that exceed present capabilities in human engineering. This international collaboration will elucidate the molecular mechanisms controlling the fabrication of these architectures. This knowledge will contribute significantly to the development of materials for advanced electronics and energy transducers, human bone therapeutics and marine-based products such as pearls and cements, through the identification of genes underlying biofabrication networks and the development of in vitro bioproduction systems.Read moreRead less
University of Queensland/Arizona State University partnership to design industrially suitable zeolite membranes for desalination. For desalination, the highest costs are organic-based membrane replacement (lasting ~1 year) and energy requirement. Functionalised zeolitic membranes are low-cost, high performing, chemically tolerant and thermally stable. New zeolite membranes in principle could perform the separation outlasting their organic counterparts, while at the same time offering major energ ....University of Queensland/Arizona State University partnership to design industrially suitable zeolite membranes for desalination. For desalination, the highest costs are organic-based membrane replacement (lasting ~1 year) and energy requirement. Functionalised zeolitic membranes are low-cost, high performing, chemically tolerant and thermally stable. New zeolite membranes in principle could perform the separation outlasting their organic counterparts, while at the same time offering major energy reductions from higher fluxes. Current zeolite membrane research for desalination however is lacking. The proposed team offers experience in bringing highly significant lab scale technologies to industrial scales. The outcomes will address mutual priorities between Australia and USA for reliable low cost supply of fresh water.Read moreRead less
Biodiversity in high rainfall mediterranean-climate ecosystems: Integrating fields of ecological enquiry to achieve improved conservation outcomes. This project targets research priority 'An Environmentally Sustainable Australia' through the management and protection of Australia's terrestrial biodiversity, and by increasing understanding of the impact of climate change and variability at the local to regional level. By linking disparate data sets across similar climatic regions, and through dir ....Biodiversity in high rainfall mediterranean-climate ecosystems: Integrating fields of ecological enquiry to achieve improved conservation outcomes. This project targets research priority 'An Environmentally Sustainable Australia' through the management and protection of Australia's terrestrial biodiversity, and by increasing understanding of the impact of climate change and variability at the local to regional level. By linking disparate data sets across similar climatic regions, and through direct links to management agencies, this project will enable development of a landscape conservation culture for improved conservation outcomes, and more direct information use through science-based adaptive management. Efficient use of existing data and the 'promotion of an innovation culture and economy' by linking global perspectives to local conservation needs, are hallmarks of this project.Read moreRead less
International Evaluation of Algorithms for Mapping in Optically Shallow Waters. This work provides a means for Australian science and management agencies to apply a method for accurately mapping shallow coastal environments. The work will build Australian research capability by developing new collaborations among experienced researchers; as well as allowing the Australian teams to benchmark their proposed methods internationally. Nationally, the work will strengthen international research exper ....International Evaluation of Algorithms for Mapping in Optically Shallow Waters. This work provides a means for Australian science and management agencies to apply a method for accurately mapping shallow coastal environments. The work will build Australian research capability by developing new collaborations among experienced researchers; as well as allowing the Australian teams to benchmark their proposed methods internationally. Nationally, the work will strengthen international research experience and generate opportunities for postgraduate and postdoctoral researchers to link into leading-edge international research networks. This work will also allow us to build strong ongoing collaborations between research teams in Australia and their counterparts overseas (specifically USA, Canada, UK and Germany). Read moreRead less
The fossil record of galaxy formation. This Australian-led team recently used the Anglo-Australian Telescope to discover large numbers of a new type of very small galaxy in the centres of two galaxy clusters. This project will maintain Australian leadership in this new area of astrophysics research, whilst using the best international expertise and facilities.
The formation and structure of distant galaxies. (i) The proposed galaxy evolution science involves the study of one of the most fundamental processes within the universe, thereby contributing to the Priority Goal of 'Breakthrough Science' under National Research Priority 3. (ii) It will bring national benefit through international collaborations with prestigious US, UK, and Canadian institutions. (iii) These collaborations will lead to new research capacity being built within Australia, with co ....The formation and structure of distant galaxies. (i) The proposed galaxy evolution science involves the study of one of the most fundamental processes within the universe, thereby contributing to the Priority Goal of 'Breakthrough Science' under National Research Priority 3. (ii) It will bring national benefit through international collaborations with prestigious US, UK, and Canadian institutions. (iii) These collaborations will lead to new research capacity being built within Australia, with considerable knowledge and expertise being vested in young postgraduate and postdoctoral researchers.Read moreRead less
Negotiating the minefield: Social conventions surrounding group criticism and their role in explaining defensiveness. People often describe the delivery of group criticism as a 'minefield', because of the potential for mistrust, hostility and defensiveness. When it comes to group criticism, being right is not enough; one must also obey certain conventions that are designed to minimize hurt and denial. In this project we explore for the first time what these 'rules of engagement' are, and what t ....Negotiating the minefield: Social conventions surrounding group criticism and their role in explaining defensiveness. People often describe the delivery of group criticism as a 'minefield', because of the potential for mistrust, hostility and defensiveness. When it comes to group criticism, being right is not enough; one must also obey certain conventions that are designed to minimize hurt and denial. In this project we explore for the first time what these 'rules of engagement' are, and what this means for those who wish to promote positive change in groups. This will have applied implications in that it will help provide specific recommendations regarding how to negotiate sensitive issues within a range of cultural, national, and corporate groups.Read moreRead less
Galaxy recycling in clusters of galaxies. Large galaxies are thought to form by merging smaller dwarf galaxies, but recent discoveries reveal a more violent picture: some dwarf galaxies are torn apart by the gravity of their companions, their contents strewn across inter-galactic space.
We will investigate how much this debris is recycled into other galaxies. We will examine Hubble Space Telescope images of dwarf galaxies to test if they are broken up to form the ultra-compact dwarf galaxies we ....Galaxy recycling in clusters of galaxies. Large galaxies are thought to form by merging smaller dwarf galaxies, but recent discoveries reveal a more violent picture: some dwarf galaxies are torn apart by the gravity of their companions, their contents strewn across inter-galactic space.
We will investigate how much this debris is recycled into other galaxies. We will examine Hubble Space Telescope images of dwarf galaxies to test if they are broken up to form the ultra-compact dwarf galaxies we recently discovered. We will model the rate at which dwarf galaxies are disrupted to determine how the dark matter is distributed in such galaxies.Read moreRead less
How does Motor Cortex Excitability Influence Internal Model Retention. Each year 40,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced quality of ....How does Motor Cortex Excitability Influence Internal Model Retention. Each year 40,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced quality of life and functional life-span, as well as significantly reduced costs of health care. In understanding the fundamental principles underlying the stability and adaptability of movement coordination, this research is likely to make a significant contribution to the design of programs for rehabilitation of the upper limb.Read moreRead less