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Early stress experiences and stress resilience in pigs. Animal stress has substantial implications on animal productivity, health and welfare of farm animals and thus farm profitability. This project aims to examine the stress resilience in pigs. Modern pig farming is a major source of food, providing substantial nutritional, social and economic benefits in Australia and worldwide. Animal welfare is of increasing concern to the public, consumers and pork producers, and stress vulnerability is an ....Early stress experiences and stress resilience in pigs. Animal stress has substantial implications on animal productivity, health and welfare of farm animals and thus farm profitability. This project aims to examine the stress resilience in pigs. Modern pig farming is a major source of food, providing substantial nutritional, social and economic benefits in Australia and worldwide. Animal welfare is of increasing concern to the public, consumers and pork producers, and stress vulnerability is an animal health and production problem in the life of the commercial pig. This project will generate new knowledge on early life management to endow stress resilience in pigs, with expected benefits for animal welfare, farm productivity and profitability.Read moreRead less
Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will ena ....Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will enable science-based guidelines, advancing disease control, local eradication, and regulatory approval for wombats. Our research framework is adaptable to other mange-impacted species, and advance methods and theory for control of treatable disease in wildlife.Read moreRead less
Targeting TGF-beta proteins to control animal reproduction. This project aims to develop a suite of novel biologics to control fertility in female mammals. This project expects to demonstrate that targeting a single class of ovarian proteins will enhance or inhibit egg production. The expected outcomes of this project are to (1) transform the breeding of livestock animals, which should provide significant benefits to the agricultural industry, through increased herd/flock sizes, and (2) provide ....Targeting TGF-beta proteins to control animal reproduction. This project aims to develop a suite of novel biologics to control fertility in female mammals. This project expects to demonstrate that targeting a single class of ovarian proteins will enhance or inhibit egg production. The expected outcomes of this project are to (1) transform the breeding of livestock animals, which should provide significant benefits to the agricultural industry, through increased herd/flock sizes, and (2) provide a non-surgical method of contraception in companion/feral species, which should address the large unmet need for fertility control in these animals.
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Utilising novel Pongamia trees to decarbonise Australia’s beef value-chain. Progress towards a carbon neutral beef industry typically focusses on nutritional strategies, overlooking potential innovations in farming system configuration. This project aims to develop a framework for the integration of Pongamia into beef production systems, so that not only emissions reductions are maximised, but also to support carbon capture and farm system resilience. This project seeks to determine the impact o ....Utilising novel Pongamia trees to decarbonise Australia’s beef value-chain. Progress towards a carbon neutral beef industry typically focusses on nutritional strategies, overlooking potential innovations in farming system configuration. This project aims to develop a framework for the integration of Pongamia into beef production systems, so that not only emissions reductions are maximised, but also to support carbon capture and farm system resilience. This project seeks to determine the impact of Pongamia meal on cattle production efficiency, meat quality and methane emissions. Through quantification of carbon sequestration potential in tree plantations, whole-farm modelling will elucidate production scenarios capable of achieving the reductions needed for a carbon neutral Australian beef industry.Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Resilience of eucalypts to future droughts. This project aims to examine how resilient Eucalyptus species are to future droughts by combining data synthesis, manipulative experiments and modelling. Climate change is expected to increase the frequency, magnitude and duration of future droughts, with major environmental and socio-economic consequences for Australia. Current predictive capacity is extremely limited: experiments are limited in scale and cannot capture important global change interac ....Resilience of eucalypts to future droughts. This project aims to examine how resilient Eucalyptus species are to future droughts by combining data synthesis, manipulative experiments and modelling. Climate change is expected to increase the frequency, magnitude and duration of future droughts, with major environmental and socio-economic consequences for Australia. Current predictive capacity is extremely limited: experiments are limited in scale and cannot capture important global change interactions, whilst models do not represent the functional characteristics and adaptions of eucalypts. This project will develop a strong evidence- and process-based understanding to quantify the functional behaviour of drought-adapted Eucalyptus species and leverage this insight to make future model projections.Read moreRead less
Transforming residues from meat processing into engineered soil amendments. The aim of this project is to transform organic residues from meat processing into agricultural soil amendments that actively improve nutrient retention and reduce nitrous oxide (a potent greenhouse gas) emissions. Current disposal and treatment options for meat processing residues are economically and environmentally unsustainable. In this research, a modified hydrothermal carbonisation process will be developed to tran ....Transforming residues from meat processing into engineered soil amendments. The aim of this project is to transform organic residues from meat processing into agricultural soil amendments that actively improve nutrient retention and reduce nitrous oxide (a potent greenhouse gas) emissions. Current disposal and treatment options for meat processing residues are economically and environmentally unsustainable. In this research, a modified hydrothermal carbonisation process will be developed to transform organic residues into novel hydrochars. The influence of these hydrochars on soil nutrient retention and nitrous oxide production will then be assessed using stable isotope tracing, genetic characterisation, and numerical modeling. The project will reduce the economic and environmental costs of organic waste disposal.Read moreRead less
New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput anal ....New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput analytical cultivation, molecular networking, and chemical and biological analyses, expected outcomes include an enhanced ability to explore and exploit valuable chemistry hidden within microbial genomes, leading to the discovery of new classes of natural antiparasitic to safeguard livestock.
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How brains become lateralised. This project aims to understand how the left and right sides of the brain become specialised for different cognitive functions, a phenomenon called lateralisation. Lateralisation is one of the least understood organisational principles of the brain, yet is crucial to the way we think and behave. Manifested most clearly as handedness, the brain is lateralised for many cognitive tasks such as language, reasoning, memory and emotion. However, the developmental origin ....How brains become lateralised. This project aims to understand how the left and right sides of the brain become specialised for different cognitive functions, a phenomenon called lateralisation. Lateralisation is one of the least understood organisational principles of the brain, yet is crucial to the way we think and behave. Manifested most clearly as handedness, the brain is lateralised for many cognitive tasks such as language, reasoning, memory and emotion. However, the developmental origin and anatomical substrate of most cognitive asymmetries are unknown. This project will use a chick model of brain lateralisation to quantify and localise to specific brain circuits the patterns of differential gene expression that give rise to anatomical and functional asymmetries.Read moreRead less
Understanding population growth time lags in invasive species. This project will use data collected from wild animals, landholder surveys, and computer simulation models to understand why invasive chital deer (Axis axis) are suddenly increasing in number after many years of slow population growth. By combining multiple empirical datasets and developing new modelling techniques, we will generate a new method for understanding population trends in introduced species. The results of this study will ....Understanding population growth time lags in invasive species. This project will use data collected from wild animals, landholder surveys, and computer simulation models to understand why invasive chital deer (Axis axis) are suddenly increasing in number after many years of slow population growth. By combining multiple empirical datasets and developing new modelling techniques, we will generate a new method for understanding population trends in introduced species. The results of this study will allow Queensland Department of Agriculture and Fisheries and others to better predict invasive species growth rates, which will allow for better, and more cost effective control methods. Read moreRead less