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Minor Use Permit For Oxytetracycline In Marine And Freshwater Crustaceans
Funder
Fisheries Research and Development Corporation
Funding Amount
$75,000.00
Summary
This project will develop a Minor Use Permit application for oxytetracycline for use in crustacean aquaculture comprising: - a human health assessment focusing on worker exposure to OTC through mixing and administration - an environment assessment comprising use of existing trigger values with estimated release volumes of chemicals to understand environmental safety and to develop environmental release conditions - an efficacy and safety summary based on published information As ....This project will develop a Minor Use Permit application for oxytetracycline for use in crustacean aquaculture comprising: - a human health assessment focusing on worker exposure to OTC through mixing and administration - an environment assessment comprising use of existing trigger values with estimated release volumes of chemicals to understand environmental safety and to develop environmental release conditions - an efficacy and safety summary based on published information Assembly of these and all other relevant data into a Minor Use Permit application and submission to APVMA. Objectives: 1. Obtain a minor use permit for oxytetracycline use in crustacean aquaculture Read moreRead less
FRDC has obtained Board approval FRDC Board Meeting # 194, 24 November 2022) to become a member of CRC SAAFE and investment up to $1.0 million. This project is needed to manage the FRDC investment that will be comprised of investments seafood related projects. Conducting projects within CRC SAAFE will provide linkages to additional resources, expertise and knowledge sharing that will improve project outputs and foster national collaboration in addition to that currently provided by the FRDC. Th ....FRDC has obtained Board approval FRDC Board Meeting # 194, 24 November 2022) to become a member of CRC SAAFE and investment up to $1.0 million. This project is needed to manage the FRDC investment that will be comprised of investments seafood related projects. Conducting projects within CRC SAAFE will provide linkages to additional resources, expertise and knowledge sharing that will improve project outputs and foster national collaboration in addition to that currently provided by the FRDC. This will include the research and industry participants that are partners of CRC SAAFE. Objectives: 1. Best practice AMR mitigation and management in the seafood industry and the aquatic environment. 2. Improved biosecurity and animal welfare through development of vaccines to minimise use of antibiotics. Read moreRead less
Development Of An Experimental Aquaculture Facility (EAF) Specific Amoebic Gill Disease (AGD) Challenge Model That Can Reliably Evaluate Treatment Interventions To Support Industry Focused AGD Studies
Funder
Fisheries Research and Development Corporation
Funding Amount
$250,000.00
Summary
Commercial in confidence. To know more about this project please contact FRDC. Objectives: Commercial in confidence
Investigating Aetiology And Risk Factors Of Ocular Lesions And Associated Mortality In Ranched Southern Bluefin Tuna
Funder
Fisheries Research and Development Corporation
Funding Amount
$200,238.00
Summary
This year (2017), some of the ranching operations reported the increased cumulative mortality. In some severe cases, up to 90% of collected mortalities present some degree of unilateral or bilateral ocular damage ranging from corneal cloudiness, with or without ulcers, up to complete perforation. The anecdotal report of eye lesions has progressively increased since the 2015 season without a definitive cause being identified. Previous reports (Rough et al., 1999; Rough, 2000; Hayward et al., 2007 ....This year (2017), some of the ranching operations reported the increased cumulative mortality. In some severe cases, up to 90% of collected mortalities present some degree of unilateral or bilateral ocular damage ranging from corneal cloudiness, with or without ulcers, up to complete perforation. The anecdotal report of eye lesions has progressively increased since the 2015 season without a definitive cause being identified. Previous reports (Rough et al., 1999; Rough, 2000; Hayward et al., 2007; Hayward et al., 2008a; Hayward et al., 2008b; Hayward et al., 2009; Hayward et al., 2010; Hayward et al., 2011, including FRDC projects No 2003/225 and 2008/228, Nowak et al., 2007; Nowak et al., 2012) identified sea lice of the genus Caligus spp. as a differential cause of eye lesions in SBT. The copepod ectoparasite is thought to damage the eyes by feeding on the cornea epithelium of infested SBT. Lesions worsen when fish flash against the cage’s net to dislodge the itchy copepods. Partial or full vision loss is suspected to impair the capacity of the fish to compete for feed and to result, with time, in the death of affected fish. At this stage, it is unclear: 1 - what is the distribution of the observed increased mortality across the industry; 2 - what is the occurrence and severity of eye lesions across the industry; 3 - if the observed increased mortality is entirely attributable to eye lesions; 4 - if eye lesions are solely caused by C. chiastos or if other causes are involved; 5 - if potential tow-, cage-, and fish-level risk factors are associated with the occurrence of eye lesions and its cause(s). Objectives: 1. Estimate the frequency and distribution of increased mortality across the industry. 2. Describe the pathology and severity of eye lesions and estimate the frequency and distribution of these lesions across the industry. 3. Investigate potential tow-, farm-, and fish-level risk factors associated with increased mortality and eye lesion occurrence. 4. Investigate the putative role of sealice in causing this episode of eye lesions. Read moreRead less
Assess The Future Needs Of Australia's Aquatic Animal Disease Diagnostic System
Funder
Fisheries Research and Development Corporation
Funding Amount
$342,866.00
Summary
Global and domestic trends in aquatic animal production and trade indicate that Australia will increasingly require agile, strong, and modern diagnostic systems to effectively manage disease risks (AQUAPLAN, 2022). To strengthen and support the aquatic animal diagnostic network we need to thoroughly understand future industry needs – which are rapidly evolving.
This project seeks to forecast diagnostic needs and understand the changing demands for aquatic animal health diagnostic servi ....Global and domestic trends in aquatic animal production and trade indicate that Australia will increasingly require agile, strong, and modern diagnostic systems to effectively manage disease risks (AQUAPLAN, 2022). To strengthen and support the aquatic animal diagnostic network we need to thoroughly understand future industry needs – which are rapidly evolving.
This project seeks to forecast diagnostic needs and understand the changing demands for aquatic animal health diagnostic services in Australia. For example, activities such as the safe translocation of stock between states, the establishment of specific pathogen free (SPF) broodstock, point-of-care-testing, emerging production diseases and increasing requirements from trading partners, will all require robust diagnostic technologies that are reliable, fit-for-purpose and accessible within the diagnostic network.
To forecast diagnostic requirements, we propose the following key activities, including a workshop (if required). The workshop is a STOP-GO point in our project and the decision to go ahead will be established in consultation with a project Steering Committee. The main activities in this project include:
1. Establishment of a Steering Committee and Terms of Reference to assist with milestone reporting and project oversight.
2. Generation of a map of the current operators and regulators of the diagnostic network for aquatic animal health in Australia.
3. Stakeholder consultation. This will be conducted incrementally through key informant interviews with the following stakeholder groups:
I. Stage 1. Members of SCAAH representing each State and Territory to identity their future needs, and further key informants. II. Stage 2A. Diagnostic service providers (Government and private veterinary laboratories identified by SCAAH) to provide insight into current diagnostic services capabilities/capacity and identify future needs. III. Stage 2B. End-users of the diagnostic network and regulators (identified by SCAAH and the research team) to provide insight into current diagnostic needs and challenges and identify future needs.
4. Scoping review of existing and novel diagnostic technologies relevant to aquatic animal health (to be conducted in parallel to the stakeholder consultation process).
5. A workshop (STOP-GO point) with key stakeholders to discuss specific needs identified in Activity 3
6. A Final Report presenting a roadmap to guide the implementation and adoption of future diagnostic needs.
Our final report and roadmap will inform priority areas for investment in the diagnostic system and provide advice to regulators. Areas for investment could include additional research and development, and upskilling of veterinary practitioners and laboratory diagnosticians. A schematic diagram of the project proposal is presented in the Appendix.
As per AQUAPLAN’s vision, this project is an exceptional opportunity to bring together a network of collaborators across multiple disciplines and sectors to support sustainable industry growth. Objectives: 1. Undertake stakeholder consultation to inform future demands on the diagnostic system over the next 5 to 10 years considering the current diagnostic landscape, and the emergence of new diagnostic needs and technologies. Read moreRead less
Aquatic Animal Health Technical Forum And Training Workshops
Funder
Fisheries Research and Development Corporation
Funding Amount
$78,000.00
Summary
There is a need to continue the workshops as they provide a forum for representatives from research institutes, Government departments and industry to discuss current aquatic animal health issues facing Australia in a friendly and collaborative setting that encourages open and frank interactions leading to improved mutual understanding of issues facing the different sectors. Workshops have been well supported and have included participants from Government and private laboratories and the aquacul ....There is a need to continue the workshops as they provide a forum for representatives from research institutes, Government departments and industry to discuss current aquatic animal health issues facing Australia in a friendly and collaborative setting that encourages open and frank interactions leading to improved mutual understanding of issues facing the different sectors. Workshops have been well supported and have included participants from Government and private laboratories and the aquaculture industry. Industry participants have been from a diversity of farms and representative of a wide variety of aquaculture species. The participant numbers have increased at each workshop from 17 to 35- ideally the maximum group size of 35. This maximum number allows the workshop to be conducted at various locations, as it is not too large a group for host facilities to accommodate. Previous workshops have led to the exchange of information and methods. This has provided ongoing contacts established at the workshops, for participants to discuss issues, and in turn, respond more effectively to disease outbreaks. With aquaculture facilities and the species farmed continuing to expand in Australia, transferring these vital skills and knowledge to a new generation of researches and those involved in aquatic animal health, will be of benefit to both the aquatic animal health sector and industries. Due to budgetary constraints in both Government and industry sectors, funding is required to assist workshop participants with travel expenses to attend the workshops. Without partial travel subsidy many forum participants would not obtain authorization to participate. This has repeatedly been raised in feedback and would affect attendance.
The exchange of information and pathways for new people involved in aquatic animal health will be lost and need to be re-established if the workshops fail to continue on an annual basis.
Objectives: 1. Source workshop venues, in various States and Territories, that have aquatic animal health capability or services and can accommodate the group size. 2. Organise all aspects of conducting the workshops including; advertising through Health Highlights subscription and peer referrals, guest presenter, presentation program, field trips and practical sessions, accommodation and catering. 3. Encourage new and emerging science and production staff to attend the AAHTF and to gain experience in making presentations 4. Continue to update the contact list and email distribution list/group for continued information exchange 5. Reports and financial acquittals prepared according to milestone schedule. Read moreRead less
South Australian Pacific Oyster Selective Breeding Program: Building POMS Resistance To Reduce Risk For The South Australian Oyster Industry
Funder
Fisheries Research and Development Corporation
Funding Amount
$936,428.00
Summary
Due to the recent detection of POMS in wild Pacific Oysters in the Port River, the SA industry urgently need POMS resistant oysters. Having POMS resistant oysters stocked onto farms prior to any potential outbreak will be critical for protecting the industry from significant losses and financial impacts.
To achieve a resistance level of over 90% for ≥ one year old oysters, the SA Pacific Oyster selective breeding program will need to establish at least three more generations of families ....Due to the recent detection of POMS in wild Pacific Oysters in the Port River, the SA industry urgently need POMS resistant oysters. Having POMS resistant oysters stocked onto farms prior to any potential outbreak will be critical for protecting the industry from significant losses and financial impacts.
To achieve a resistance level of over 90% for ≥ one year old oysters, the SA Pacific Oyster selective breeding program will need to establish at least three more generations of families for genetic improvement after the completion of the Future Oysters CRC-P project in 2019.
Establishing the SA Pacific Oyster selective breeding program requires specific techniques and skills. SARDI is the only organisation in SA that has the purpose-built hatchery facility for this species and has produced target numbers of Pacific Oyster families over the last three seasons. SARDI also has a well-established team in oyster genetics and bivalve hatchery technologies.
To support the Stage 2 development of the SA selective breeding program, Flinders Ports, in partnership with the Fisheries Research and Development Corporation (FRDC), ASI, SAOGA and PIRSA-SARDI will jointly fund this project for the SA oyster industry to address POMS risks, and further mitigate the risk factors associated with the spread of POMS outside the Port River related to dredging activities in the Outer Harbour.
Objectives: 1. Develop selective families with 90% POMS disease resistance for ≥ one year old Pacific Oysters 2. Support the SA industry by provision of high POMS resistant broodstock for commercial spat production Read moreRead less
A Trivalent Vaccine For Sustainable Yellowtail Kingfish Growout
Funder
Fisheries Research and Development Corporation
Funding Amount
$809,040.00
Summary
Optimised vaccines deliver improved animal health and avoid use of antimicrobials in the production of fish (Sommerset et al., Expert Review Vaccines 2005, 4, 89-101.). Australian YTK Photobacteriosis outbreaks have been reported in association with Photobacterium damselae subsp damselae (Pdd), Photobacterium damselae subspecies piscicida(Pdp) and various Vibrio harveyi(Vh) isolates (Matt Landos, Nicky Buller, unpublished). To support stable production of high quality finfish highly efficacious ....Optimised vaccines deliver improved animal health and avoid use of antimicrobials in the production of fish (Sommerset et al., Expert Review Vaccines 2005, 4, 89-101.). Australian YTK Photobacteriosis outbreaks have been reported in association with Photobacterium damselae subsp damselae (Pdd), Photobacterium damselae subspecies piscicida(Pdp) and various Vibrio harveyi(Vh) isolates (Matt Landos, Nicky Buller, unpublished). To support stable production of high quality finfish highly efficacious controls of microbial diseases are critical. Successful examples are currently employed in salmon (Yersinia ruckeri, Vibrio anguillarum) and barramundi (Streptococcus iniae) whereby disease outbreaks drove the need for vaccine development. These conditions are now both well controlled in vaccinated populations and have dramatically reduced reliance on administration of antibiotics. Currently, crude autogenous vaccines are in use with YTK for control of only Pdd in South Australia and Western Australia with some reported success. Recently Pdp has emerged as a significant pathogen in South Australian outbreaks. Reliable vaccination against Pdp has proven difficult in international experience using traditional autogenous and generic killed vaccine methods, hence increasingly research is exploring DNA vaccination methods to improve protection against this pathogen (Kato et al., Vaccine 2015, 33 (8), 1040-1045). It is also probable that antigenic diversity had been underestimated, given high diversity that recent sequencing technology has revealed in our preliminary research . Preparedness for the emergence of highly pathogenic Pdp strains is prudent to allow rapid controls to be developed, without incurring business-ending losses within the growing aquaculture sector, or having high levels of reliance on oral antibiotics. Genetic sequence data on isolates generated through this project can be used for epidemiological modelling, new rapid diagnostic typing tools and immediate response if disease emergence occurs in other finfish industries. Pdp is acknowledged as a serious pathogen internationally in species including yellowtail, cobia, flounder, seabream, pompano and sea bass. (Andreoni et al.J Immunol Res. 2014).
Objectives: 1. Generate comprehensive genome database of Australian isolates of Pdd, Pdp and Vh associated with Photobacteriosis outbreaks in YTK 2. Generate and supply diagnostic laboratory reagents and methods for typing Photobacterium and Vibrio isolates associated with YTK outbreaks. 3. Deliver optimised monovalent and multivalent (Pdd, Pdp, Vh) killed vaccines, with production outline, appropriate adjuvant type, dose, safety and efficacy profile in YTK, ready for manufacture. Read moreRead less