Brain Regulation of Reproduction: Challenging the ‘KNDy’ Hypothesis. The brain switches reproduction on and off by changing the frequency of pulses of gonadotrophin releasing hormone. The processes that produce the pulses have been a puzzle for decades but, recently, brain cells that produce three peptides (kisspeptin, neurokinin B, dynorphin), known as ‘KNDy cells’, have been heralded as the ‘missing link’, or even the ‘pulse generator’. Using sheep, this project will challenge the KNDy hypothe ....Brain Regulation of Reproduction: Challenging the ‘KNDy’ Hypothesis. The brain switches reproduction on and off by changing the frequency of pulses of gonadotrophin releasing hormone. The processes that produce the pulses have been a puzzle for decades but, recently, brain cells that produce three peptides (kisspeptin, neurokinin B, dynorphin), known as ‘KNDy cells’, have been heralded as the ‘missing link’, or even the ‘pulse generator’. Using sheep, this project will challenge the KNDy hypothesis with pheromones and with acute increases in nutrition, two factors that rapidly increase the frequency of gonadotrophin releasing hormone pulses. The outcomes of this research are directly relevant to the optimisation of reproductive management in farm animals, wildlife and humans.Read moreRead less
The molecular basis of sperm competition. This project aims to unravel the molecular basis of reproductive conflicts. Males compete for paternity and this continues after mating if females copulate and receive semen from multiple males. In ants and bees, molecules in males’ ejaculates recognise and kill rival males’ sperm. Reproductive proteins in leaf cutter ants’ seminal fluid may be the molecular agents of sperm competition. This project will investigate reproductive proteins and their functi ....The molecular basis of sperm competition. This project aims to unravel the molecular basis of reproductive conflicts. Males compete for paternity and this continues after mating if females copulate and receive semen from multiple males. In ants and bees, molecules in males’ ejaculates recognise and kill rival males’ sperm. Reproductive proteins in leaf cutter ants’ seminal fluid may be the molecular agents of sperm competition. This project will investigate reproductive proteins and their functioning and effects on reproductive success. This project will show how reproductive conflicts over paternity operate on the protein level and may lead to novel avenues for future pest control.Read moreRead less
Evolutionary proteomics of social insects. This project aims to understand the molecular mechanisms that affect fertility in honeybees and leaf-cutting ants by identifying the function of proteins in male and female secretions related to insemination and sperm storage. The understanding of these general principles will have important applications for honeybee breeding.
Discovery Early Career Researcher Award - Grant ID: DE130101660
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
The secret of bee navigation: magnetic field sensitive cells in the honeybee Apis mellifera. Honeybees are known to use the Earth's geomagnetic field to orient themselves and carry out their vital role as crop pollinators and honey producers. Locating and characterising the cells responsible for this magnetic sense is of great significance to neuroscience and will provide important new insights into animal behaviour and ecology.
Ecological immunity in the Lepidoptera: unravelling the relationship between immune function, sperm quality, and reproductive success. The effect of juvenile immune challenge and an individual's population ecology on subsequent adult immune function, physiology and reproductive success is poorly understood, despite its ability to explain fundamental processes in sexual selection. This project will unravel the relationship between immune function, sperm quality, and reproductive success.
Polarization vision: insights from biological systems for imaging solutions. This project aims to discover how invertebrate and vertebrate model species see linearly polarised light by constructing a novel instrument to determine limits to sensitivities, as well as animals' ability to distinguish small differences in degree and angle of linear polarisation. The project aims to predict how this might be affected as environments change. A clear understanding of biological solutions to polarisation ....Polarization vision: insights from biological systems for imaging solutions. This project aims to discover how invertebrate and vertebrate model species see linearly polarised light by constructing a novel instrument to determine limits to sensitivities, as well as animals' ability to distinguish small differences in degree and angle of linear polarisation. The project aims to predict how this might be affected as environments change. A clear understanding of biological solutions to polarisation perception can inform the design and development of novel bio-inspired imaging sensors that will be particularly suited to small, autonomous robots.Read moreRead less
Linking evolutionary and molecular biology to safeguard Australian honeybees. Honeybee populations are declining globally but their pollination services are of central importance for food production. This project will study honeybee proteins that influence both fertility and immunity and their effects in vivo. This knowledge is of interest for the bee breeding industry to avoid or combat bee declines in managed Australian bees.
Bio-inspired camouflage to prevent shark attacks on surfers. Bio-inspired camouflage to prevent shark attacks on surfers. This project aims to develop a new shark deterrent technology to protect surfers and paddlers. Shark attacks are physically and emotionally devastating for the victims, and make the community disproportionately afraid. Surfers are at most risk of attack, but current surfboard-mounted deterrents are ineffective and not widely used. This project will build on the recent discove ....Bio-inspired camouflage to prevent shark attacks on surfers. Bio-inspired camouflage to prevent shark attacks on surfers. This project aims to develop a new shark deterrent technology to protect surfers and paddlers. Shark attacks are physically and emotionally devastating for the victims, and make the community disproportionately afraid. Surfers are at most risk of attack, but current surfboard-mounted deterrents are ineffective and not widely used. This project will build on the recent discovery that white sharks do not attack counter-illuminated (light emitting) seal-shaped decoys, and use new information about shark vision to understand why this ‘camouflage’ is so successful. This will also help to protect threatened shark species by reducing reliance on culling programs to keep people safe in the water.Read moreRead less
RoboCrab: An integrative approach to the natural ecology of decision making. The project aims to analyse and model the sophisticated and context-dependent escape behaviour of fiddler crabs under both natural conditions and in controlled laboratory settings. A crucial problem for biology is to understand how animals can make adaptive decisions in natural, complex sensory environments; such understanding also has direct application to robotics. The project plans to examine the effects of eye stabi ....RoboCrab: An integrative approach to the natural ecology of decision making. The project aims to analyse and model the sophisticated and context-dependent escape behaviour of fiddler crabs under both natural conditions and in controlled laboratory settings. A crucial problem for biology is to understand how animals can make adaptive decisions in natural, complex sensory environments; such understanding also has direct application to robotics. The project plans to examine the effects of eye stabilisation and oscillation, record from key neural stages using naturalistic stimuli to derive precise algorithms, and integrate and test the results on a robot model – RoboCrab. This may provide new insight into the integration of low-level sensory input with behavioural decision making circuits and the evolution of escape behaviours.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100126
Funder
Australian Research Council
Funding Amount
$160,000.00
Summary
Expanding capability in Western Australian flow cytometry for earth, oceans, environmental and biomedical science: state-of-the-art four laser and 12 colour analysis. This multiparameter flow cytometry facility will find wide application in the biological and environmental sciences, including analysis: of cells in vertebrates giving new understanding of cognitive development; of parasites and bacteria leading to new animal vaccines; and of marine plankton leading to more sustainable ecosystems a ....Expanding capability in Western Australian flow cytometry for earth, oceans, environmental and biomedical science: state-of-the-art four laser and 12 colour analysis. This multiparameter flow cytometry facility will find wide application in the biological and environmental sciences, including analysis: of cells in vertebrates giving new understanding of cognitive development; of parasites and bacteria leading to new animal vaccines; and of marine plankton leading to more sustainable ecosystems and fisheries.Read moreRead less