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Research Topic : Animal Models
Australian State/Territory : WA
Socio-Economic Objective : Expanding Knowledge in Technology
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  • Funded Activity

    Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100056

    Funder
    Australian Research Council
    Funding Amount
    $621,198.00
    Summary
    High-frequency ultrasound and photoacoustic imaging for Western Australia. This project aims to obtain a small animal, high-frequency ultrasound and photoacoustic imaging instrument, to be placed in the University of Western Australia's Centre for Microscopy, Characterisation and Analysis. As a node of the National Imaging Facility, this infrastructure will result in enhanced capacity for fundamental, interdisciplinary, biological, and bionanotechnology research in Western Australia, and enable .... High-frequency ultrasound and photoacoustic imaging for Western Australia. This project aims to obtain a small animal, high-frequency ultrasound and photoacoustic imaging instrument, to be placed in the University of Western Australia's Centre for Microscopy, Characterisation and Analysis. As a node of the National Imaging Facility, this infrastructure will result in enhanced capacity for fundamental, interdisciplinary, biological, and bionanotechnology research in Western Australia, and enable pursuit of projects previously only possible either interstate or internationally. New capacity in small animal in-vivo imaging will generate knowledge in biology, feeding into such areas as species conservation and reproductive health, and intellectual property and commercial opportunity in areas such as medical imaging and theranostics.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP220102042

    Funder
    Australian Research Council
    Funding Amount
    $485,575.00
    Summary
    Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn .... Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.
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    Funded Activity

    Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100146

    Funder
    Australian Research Council
    Funding Amount
    $500,000.00
    Summary
    Multiphoton confocal microscope for high-speed, deep tissue imaging and multimodal nanoscale characterisation. This facility will provide the ability to optically section deep nanoparticles, cells, tissues and whole animals at high speed with unsurpassed spatial resolution at the atomic level. It will give biomedical, physical and life scientists and materials engineers the opportunity to image a range of dynamic processes and reconstruct these in three dimensions for the first time.
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