Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100213
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Advanced fluorescence characterisation facility. Fluorescence is the emission of light by a substance that has absorbed light of a different wavelength. Fluorescence techniques and fluorescent molecules have enabled a great many of the most important advances in biology, chemistry and medicine in recent decades. This facility will support a wide range of research projects using or exploring fluorescence and luminescence. The research supported will underpin advances in diverse scientific fields.
New strategies for highly sensitive chemical detection based on luminescent ruthenium and iridium complexes. Chemical reactions that emit tiny quantities of light, not even visible to the naked eye, can be used to detect the biomarkers of disease or traces of chemical or biological weapons in a terrorist attack. This project creates a new generation of reagents for this remarkably sensitive mode of detection for these and other important applications.
Probing antimicrobial drug resistance by multimodal molecular analysis. This project aims to investigate drug resistance in microbial agents. With the emergence of "super bugs" there is a need to understand the biochemistry of antimicrobial resistance. Combining vibrational spectroscopic approaches and metabolomic techniques, the project will investigate cell populations, single cells and subcellular structures in search of biomarkers for drug resistance. The discovery of such biomarkers could l ....Probing antimicrobial drug resistance by multimodal molecular analysis. This project aims to investigate drug resistance in microbial agents. With the emergence of "super bugs" there is a need to understand the biochemistry of antimicrobial resistance. Combining vibrational spectroscopic approaches and metabolomic techniques, the project will investigate cell populations, single cells and subcellular structures in search of biomarkers for drug resistance. The discovery of such biomarkers could lead to improved disease management and eradication programs through identification and treatment of drug resistant pathogens in individuals that have the potential to re-infect the community.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100035
Funder
Australian Research Council
Funding Amount
$4,958,927.00
Summary
ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, ....ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, providing the materials and inspiration for young researchers to apply novel hyphenated methods to complex environmental and industrial systems. This Centre will deliver fundamental developments in hyphenated technologies, new analytical capability, and applied outcomes across multiple end-user groups and interests. Read moreRead less
New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordi ....New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordinary people to gain knowledge about the concentrations of molecular compounds in their environments and in themselves. This will stimulate economic and social benefits related to environmental testing and early disease diagnosis and generate new commercial opportunities for the Australian biotechnology industry.Read moreRead less
Microfluidic Separation Science: Innovative Technology for Characterising Complex Chemical Systems. At present there is a need for fast and detailed chemical analysis of complex samples, such as those important to biomedical diagnostics and forensic science. Innovative technology will be developed here in order to reduce analysis time whilst maintaining the integrity of the chemical information contained within the sample. This step change in separation science will directly aid biomedical diagn ....Microfluidic Separation Science: Innovative Technology for Characterising Complex Chemical Systems. At present there is a need for fast and detailed chemical analysis of complex samples, such as those important to biomedical diagnostics and forensic science. Innovative technology will be developed here in order to reduce analysis time whilst maintaining the integrity of the chemical information contained within the sample. This step change in separation science will directly aid biomedical diagnostics, forensic sample determination and industrial process monitoring through decreased analysis time with an increase in the chemical information gained. By performing chemical separations on a microfluidic scale a reduction in both the cost of analysis and impact of solvent waste on the environment will be achieved.Read moreRead less
Rapid amperometric measurement of chemical oxygen demand in polluted water based on electrochemical and photocatalytic properties of nanoparticulates. The project will enhance a newly developed technology for measuring aggregate organic pollution in wastewater. The conventional wet chemistry method is disadvantaged by being slow (2 hr) and requiring toxic heavy metal (mercury, chromium) and hazardous reagents. Aqua Diagnostic's method, by contrast, is rapid (5-10 minutes) and uses only safe ch ....Rapid amperometric measurement of chemical oxygen demand in polluted water based on electrochemical and photocatalytic properties of nanoparticulates. The project will enhance a newly developed technology for measuring aggregate organic pollution in wastewater. The conventional wet chemistry method is disadvantaged by being slow (2 hr) and requiring toxic heavy metal (mercury, chromium) and hazardous reagents. Aqua Diagnostic's method, by contrast, is rapid (5-10 minutes) and uses only safe chemical reagents. It will be further improved to facilitate unprecedented near-real-time (less than 1 minute) online pollution monitoring and greater analytical robustness. The project will directly benefit the wastewater management community, enrich Australian industry's expertise in nanotechnology applications and grow high-tech exports as this innovative technology continues to penetrate international markets.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100094
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
Macromolecular characterisation and purification facility. In-depth characterisation of (bio)macromolecules and nanomaterials is fundamental to understanding their properties and application to advanced materials and technologies. The three new instruments at this facility dedicated to the purification, separation and characterisation of these compounds will provide an essential resource for polymer/materials research.
Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materia ....Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materials and biomedical engineering, the project will contribute to the training of young researchers in these emerging technologies which interest Nutromics Pty Ltd. The project will improve Australia's standing in technology around wearable devices, improving our global competitive edge with economic and scientific impact.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101253
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
Redox-mediated electrochemiluminescence enhancement for novel biosensors. This project aims to understand and apply a novel approach to the enhancement of diagnostic tests for agricultural biosecurity applications. Government and Industry require simple, rapid tests to monitor and detect threats to Australia’s agricultural biosecurity. This interdisciplinary project intends to enhance collaboration, generate fundamental advances in the field of analytical chemistry and bolster Australia’s resear ....Redox-mediated electrochemiluminescence enhancement for novel biosensors. This project aims to understand and apply a novel approach to the enhancement of diagnostic tests for agricultural biosecurity applications. Government and Industry require simple, rapid tests to monitor and detect threats to Australia’s agricultural biosecurity. This interdisciplinary project intends to enhance collaboration, generate fundamental advances in the field of analytical chemistry and bolster Australia’s research capabilities through new analytical techniques and technologies. The breadth of applications of this technology should also provide significant benefits to the Australian biotechnology industry, improve existing instrumentation and impact diverse research fields from biosecurity to health monitoring.
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