Lab-on-a-chip mass spectrometry tools for testing illicit drugs. This project aims to develop fit-for-purpose mass spectrometry tools for roadside and workplace testing of illicit drugs. The technology will be based on nanostructured semiconductor chips that are surface-functionalised to enable molecular capture without extensive sample processing and subsequent detection by a novel combination of techniques. The technology is expected to be applicable to saliva, sweat and urine samples.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346895
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
A Mass Directed Molecular Resolution Laboratory. The proposed "Mass Directed Molecular Resolution Laboratory" combines an integrated suite of instrumentation housed in purpose built laboratories with technical expertise to provide an unique "one stop shop" to meet the burgeoning mass spectrometry needs of the chemical community in the Melbourne area. This truly collaborative effort will service the needs of 17 research groups with 92 PhD students and post doctoral researchers and will enhance ex ....A Mass Directed Molecular Resolution Laboratory. The proposed "Mass Directed Molecular Resolution Laboratory" combines an integrated suite of instrumentation housed in purpose built laboratories with technical expertise to provide an unique "one stop shop" to meet the burgeoning mass spectrometry needs of the chemical community in the Melbourne area. This truly collaborative effort will service the needs of 17 research groups with 92 PhD students and post doctoral researchers and will enhance existing excellence in a range of areas. Finally, the laboratory will provide opportunities to: collaborate and consult with industry; train postgraduate students in instrumentation used at the cutting edge of chemical and biochemical sciences.Read moreRead less
Novel nanosensors for monitoring of water filtration membrane integrity. Novel nanosensors for monitoring of water filtration membrane integrity. This project aims to develop arrays of electrochemical biosensors based on nanostructured silicon for real-time monitoring of water filtration membrane integrity. Real-time monitoring of membrane performance, based on removing virus-sized particles, is a priority for the water industry to maximise asset life and meet increased demand for safe and high- ....Novel nanosensors for monitoring of water filtration membrane integrity. Novel nanosensors for monitoring of water filtration membrane integrity. This project aims to develop arrays of electrochemical biosensors based on nanostructured silicon for real-time monitoring of water filtration membrane integrity. Real-time monitoring of membrane performance, based on removing virus-sized particles, is a priority for the water industry to maximise asset life and meet increased demand for safe and high-quality water. Materials scientists, electrochemists, and specialists in water management and reuse aim to harness advances in nanostructured transducers and electrochemical protocols to develop online performance-monitoring technology. This project is expected to improve water treatment processes, removing viruses and reducing the risks and uncertainties of water recycling.Read moreRead less
Special Research Initiatives - Grant ID: SR180100005
Funder
Australian Research Council
Funding Amount
$1,225,000.00
Summary
Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The proj ....Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The project will provide a scientific basis for understanding the benefits and limitations associated with soil washing and immobilisation techniques and a more comprehensive understanding of future liabilities associated with formation of PFASs from precursors remaining in remediated soils. Collaboration with stakeholders will ensure benefits are captured both commercially and environmentally, as well as removing a potential and on-going health threat to communities exposed to these contaminants.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100094
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
Macromolecular characterisation and purification facility. In-depth characterisation of (bio)macromolecules and nanomaterials is fundamental to understanding their properties and application to advanced materials and technologies. The three new instruments at this facility dedicated to the purification, separation and characterisation of these compounds will provide an essential resource for polymer/materials research.
Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lip ....Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lipid biology at the cellular and sub-cellular level across a wide range of in vitro and in vivo models. The outcomes of this project should provide significant knowledge to tackle modern societal challenges in healthy ageing, brain pathologies and neurodegenerative diseases.Read moreRead less
Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This projec ....Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This project will push the boundaries of a variety of micro and nano "probe-free" microscopies to provide fundamental insights into these life processes, which could ultimately lead to improvements in the diagnosis, prevention and treatment of diseases.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100040
Funder
Australian Research Council
Funding Amount
$4,997,903.00
Summary
ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB). The Centre for Facilitated Advancement of Australia's Bioactives (FAAB) will transform the rapidly growing bioactive ingredients sector. It will apply advanced analytical methods to molecular characterisation of bioactive products derived from foods, food-waste, and cell-based biotechnologies. FAAB will determine modes of action for bioactives with potential lifestyle and nutritional benefits allowing for evidence- ....ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB). The Centre for Facilitated Advancement of Australia's Bioactives (FAAB) will transform the rapidly growing bioactive ingredients sector. It will apply advanced analytical methods to molecular characterisation of bioactive products derived from foods, food-waste, and cell-based biotechnologies. FAAB will determine modes of action for bioactives with potential lifestyle and nutritional benefits allowing for evidence-informed decision-making, and regulatory framework development. FAAB graduates will lead and deliver future national self-reliance to the Australian bioactives sector, increasing diversification and international competitiveness and development of regulation in a growing market. Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC140100022
Funder
Australian Research Council
Funding Amount
$2,148,935.00
Summary
ARC Training Centre for Portable Analytical Separation Technologies. ARC Training Centre for Portable Analytical Separation Technologies. Portable analytical separation systems will enable point-of sample analysis for complex samples in food, environmental and clinical applications. The Training Centre aims to train the next generation of industry-ready Australian researchers through creating a sustainable research partnership between university-based researchers and Australian industry focused ....ARC Training Centre for Portable Analytical Separation Technologies. ARC Training Centre for Portable Analytical Separation Technologies. Portable analytical separation systems will enable point-of sample analysis for complex samples in food, environmental and clinical applications. The Training Centre aims to train the next generation of industry-ready Australian researchers through creating a sustainable research partnership between university-based researchers and Australian industry focused on developing new capabilities and technologies that have the potential to facilitate, support, or catalyse the progressive deployment of portable separation science technologies into society. This will enable the development of new, portable and affordable analytical separation systems and contribute to creating a sustainable, globally competitive manufacturing industry in Australia.Read moreRead less