ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions i ....ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions in science. An essential function of the network will be introducing researchers end users to new tools and broadening the horizons of graduate students.Read moreRead less
ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. The ARC Centre for the Mathematical Analysis of Cellular Systems aims to deliver the mathematics required to compute life. The Centre will deliver innovation in computational and mathematical biology and establish in silico biology alongside in vivo and in vitro biology. These models will allow us to understand the complexity of life at the cellu ....ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems. The ARC Centre for the Mathematical Analysis of Cellular Systems aims to deliver the mathematics required to compute life. The Centre will deliver innovation in computational and mathematical biology and establish in silico biology alongside in vivo and in vitro biology. These models will allow us to understand the complexity of life at the cellular level and enable new ways of combining diverse and heterogenous data. This will allow us to understand the mechanisms underlying cellular behaviour, and to apply rational design engineering methods in order to control the dynamics of biological systems. Read moreRead less
Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of posit ....Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of positron transport in PET. The project will allow validation of predictions from the model by undertaking experiments in liquid water.Read moreRead less
Non-equilibrium presolvation electron processes at the gas-liquid interface. The interaction of low-temperature plasma electrons with liquids has served as a reducing agent in various technological applications in water treatment, agriculture, biofuels and medicine. Predictive control of the plasma-liquid interface is essential to unlocking the potential of these applications, and this has been limited by the absence of the relevant non-equilibrium transport theory describing electrons at the pl ....Non-equilibrium presolvation electron processes at the gas-liquid interface. The interaction of low-temperature plasma electrons with liquids has served as a reducing agent in various technological applications in water treatment, agriculture, biofuels and medicine. Predictive control of the plasma-liquid interface is essential to unlocking the potential of these applications, and this has been limited by the absence of the relevant non-equilibrium transport theory describing electrons at the plasma-liquid interface together with fundamental data describing electron interactions with liquids. The project will develop a state of the art presolvation electron transport model informed by world first measurements of electron cross-sections for radicals and liquids and apply it to model plasma electrochemistry processes.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100151
Funder
Australian Research Council
Funding Amount
$744,000.00
Summary
Multi-kilohertz laser for attosecond and ultrafast science. Griffith University's Australian Attosecond Science Facility was established 12 years ago to facilitate internationally leading research into strong-field laser science. The facility is unique in Australia as it has the capability to precisely manipulate highly-amplified and ultra-short light pulses to investigate the dynamics of matter. The scientific outputs from the facility have delivered important new scientific advances in strong ....Multi-kilohertz laser for attosecond and ultrafast science. Griffith University's Australian Attosecond Science Facility was established 12 years ago to facilitate internationally leading research into strong-field laser science. The facility is unique in Australia as it has the capability to precisely manipulate highly-amplified and ultra-short light pulses to investigate the dynamics of matter. The scientific outputs from the facility have delivered important new scientific advances in strong-field physics enabling the development of new technologies. This grant will be used to procure an upgraded laser system enabling an order of magnitude enhancement of the output light for the next-generation research and maintaining international competitiveness of Australian investigators in this field.Read moreRead less
Electron scattering and transport for plasma-liquid interactions. The project aims to address the emerging technologies associated with the interaction of plasmas with liquids and biological matter, including plasma medicine. The project expects to generate new knowledge on the role of electron-induced processes through the development of complete and accurate sets of microscopic cross-sections for electrons with biomolecules within tissue. This microscopic data will inform new microscopic model ....Electron scattering and transport for plasma-liquid interactions. The project aims to address the emerging technologies associated with the interaction of plasmas with liquids and biological matter, including plasma medicine. The project expects to generate new knowledge on the role of electron-induced processes through the development of complete and accurate sets of microscopic cross-sections for electrons with biomolecules within tissue. This microscopic data will inform new microscopic models for non-equilibrium electron transport in liquids and biological matter, and its coupling to plasmas. The expected outcomes of this project include progress towards the optimisation of safety/efficacy of future generation plasma medicine devices through detailed understanding of plasma-biological tissue interactions.Read moreRead less
Classification methods for providing personalised and class decisions. This project provides a novel approach to the clustering of multivariate samples on entities in a class that automatically matches the sample clusters across the entities, allowing for inter-sample variation between the samples in a class. The project aims to develop a widely applicable, mixture-model-based framework for the simultaneous clustering of multivariate samples with inter-sample variation in a class and for the mat ....Classification methods for providing personalised and class decisions. This project provides a novel approach to the clustering of multivariate samples on entities in a class that automatically matches the sample clusters across the entities, allowing for inter-sample variation between the samples in a class. The project aims to develop a widely applicable, mixture-model-based framework for the simultaneous clustering of multivariate samples with inter-sample variation in a class and for the matching of the clusters across the entities in the class. The project will use a statistical approach to automatically match the clusters, since the overall mixture model provides a template for the class. It will provide a basis for discriminating between different classes in addition to the identification of atypical data points within a sample and of anomalous samples within a class. Key applications include biological image analysis and the analysis of data in flow cytometry which is one of the fundamental research tools for the life scientist.Read moreRead less
ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reac ....ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reactions and how higher brain function emerges from networks of neurons. By building a diverse, multidisciplinary, and industry-engaged ecosystem, the Centre means to develop our future leaders at the interface of quantum science and biology and drive Australian innovation across manufacturing, energy, agriculture, health, and national security.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101565
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Flexible data modelling via skew mixture models:challenges and applications. This project seeks to explore new models for handling data with non-normal features. Parametric distributions are fundamental to statistical modelling and inference. For centuries, the ‘normal’ distribution has been the dominant model for continuous data. However, real data rarely satisfy the assumption of normality. There is thus a strong demand for more flexible distributions. This project aims to develop new methodol ....Flexible data modelling via skew mixture models:challenges and applications. This project seeks to explore new models for handling data with non-normal features. Parametric distributions are fundamental to statistical modelling and inference. For centuries, the ‘normal’ distribution has been the dominant model for continuous data. However, real data rarely satisfy the assumption of normality. There is thus a strong demand for more flexible distributions. This project aims to develop new methodologies in finite mixture modelling using skew component distributions to provide better models for handling data with non-normal features (such as skewness, heavy/light tails, and multimodality). Applications may include security intrusion detection, clinical diagnosis and prognosis, and flow and mass cytometry.Read moreRead less
Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interact ....Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interactions, developing an efficient, clean source of excited metastable atoms, and integrating that source into the Australian National Facility for dating geological samples. This should provide significant benefits, such as significant improvement of operational efficiency and productivity of that facility.Read moreRead less