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Modelling and manipulating brain network dynamics across the lifespan. This project aims to integrate advanced computational modelling and state-of-the-art recording techniques to generate new knowledge on the neural basis of ageing. People are said to grow wiser as they grow older, though more likely they will experience cognitive slowing and reduced memory functions that interfere with their daily lives. The anticipated goal of the project is to develop techniques to predict the personalised e ....Modelling and manipulating brain network dynamics across the lifespan. This project aims to integrate advanced computational modelling and state-of-the-art recording techniques to generate new knowledge on the neural basis of ageing. People are said to grow wiser as they grow older, though more likely they will experience cognitive slowing and reduced memory functions that interfere with their daily lives. The anticipated goal of the project is to develop techniques to predict the personalised effects of brain stimulation on the ageing brain. The outcomes of this research could significantly improve understanding of brain ageing, and advance the fields of systems neuroscience, network science, and brain stimulation.Read moreRead less
An anti-senescence nanoplatform and its underlying mechanism. The project will bring together complementary expertise and skills by combining biomaterials, cell and molecular biology, and engineering, to develop a novel nano-biomaterial platform for anti-senescence and gain an in-depth understanding of its underlying mechanisms. The underlying mechanisms of senescence remain elusive and bone substitutes with anti-senescence property have not been explored and becoming a growing field of interest ....An anti-senescence nanoplatform and its underlying mechanism. The project will bring together complementary expertise and skills by combining biomaterials, cell and molecular biology, and engineering, to develop a novel nano-biomaterial platform for anti-senescence and gain an in-depth understanding of its underlying mechanisms. The underlying mechanisms of senescence remain elusive and bone substitutes with anti-senescence property have not been explored and becoming a growing field of interest in bone regeneration. The project will develop a well-defined and efficient nanomaterial platform with optimal combination of nano-surface features and chemistry for cell rejuvenation, and it will give unprecedented depth of interdisciplinary understanding of senescence rejuvenation mechanisms.Read moreRead less
Efficient learning from multiple brain imaging data sets. Brain imaging data analysis methods have proven to be very effective in the study of brain functions and the identification of brain disorders because they minimise the modelling assumptions on the underlying structure of the problem. Analysis of multiple brain imaging data sets, either of the same modality as in multitask or multisubject data sets or from different modalities as in the case of data fusion, is a challenging problem in bi ....Efficient learning from multiple brain imaging data sets. Brain imaging data analysis methods have proven to be very effective in the study of brain functions and the identification of brain disorders because they minimise the modelling assumptions on the underlying structure of the problem. Analysis of multiple brain imaging data sets, either of the same modality as in multitask or multisubject data sets or from different modalities as in the case of data fusion, is a challenging problem in biomedical image analysis. This project will lead to fundamental contributions as well as techniques that address both problems: extraction of relevant features information from multisubject brain imaging data sets of the same modality or from fusion of brain imaging data sets collected from multimodalities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100200
Funder
Australian Research Council
Funding Amount
$270,427.00
Summary
AutoStem: a high performance, automated stem cell bioengineering facility. This project aims to establish an automated stem cell bioengineering ("AutoStem") facility that will enable critical insights into the molecular mechanisms that underly the loss in stem cell function and tissue homeostasis as we age. The AutoStem facility expects to lead to the discovery of the key drivers of stem cell ageing and the development of novel technological solutions to maintain tissue function with age. The o ....AutoStem: a high performance, automated stem cell bioengineering facility. This project aims to establish an automated stem cell bioengineering ("AutoStem") facility that will enable critical insights into the molecular mechanisms that underly the loss in stem cell function and tissue homeostasis as we age. The AutoStem facility expects to lead to the discovery of the key drivers of stem cell ageing and the development of novel technological solutions to maintain tissue function with age. The outcomes produced from the AutoStem facility will have significant economic and social benefits in enabling healthy ageing and increased productivity for an ageing Australia.Read moreRead less
Engineering the convergence of telecare and telehealth. This project will design a wrist-worn pendant that represents the convergence of telecare (fall detection and personal alarm pendants) and telehealth (remote management of chronic disease). The system has the potential to be retro-fitted to 100,000s of telecare systems deployed by an industry partner and to herald a new form of low-cost patient monitoring.
The development of flexible, graded plasma surface engineered coatings for superior interfacial performance. The next generation of intraocular lenses, medical devices to treat patients with cataracts, will be developed through application of advanced surface engineering technologies. These superior coated lenses will improve biocompatibility and function, leading to additional benefit for the forecasted 2.7 million Australians with cataracts by 2021.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100003
Funder
Australian Research Council
Funding Amount
$318,900.00
Summary
Vector network analyser suite for advanced terahertz materials and devices. This project aims to establish terahertz measurement capabilities to further Australia's strength and momentum in terahertz research. This will comprise of two terahertz extension modules, working with a dedicated vector-network analyser, and high-precision probes and probe station. The project will enable point-feeding, monochromatic, coherent, and fine spectral-resolution measurement at an atmospheric window of 220-330 ....Vector network analyser suite for advanced terahertz materials and devices. This project aims to establish terahertz measurement capabilities to further Australia's strength and momentum in terahertz research. This will comprise of two terahertz extension modules, working with a dedicated vector-network analyser, and high-precision probes and probe station. The project will enable point-feeding, monochromatic, coherent, and fine spectral-resolution measurement at an atmospheric window of 220-330 GHz. The capabilities are essential for development of two-dimensional materials, active components, waveguides, and antennas towards a common goal of efficient integrated terahertz devices and systems. The project will serve emerging terahertz applications including standoff imaging and short-range high-speed data transmission. This will have broad impact in the areas of surveillance, biomedicine, security, and public safety and well-being.Read moreRead less
Engineering high-efficiency all-dielectric antennas for terahertz channels. This project aims to create unconventional antenna platforms to support terahertz links. The project expects to deliver high-efficiency, high-gain dielectric resonator antennas and dielectric rod antenna arrays fed by dielectric wave-guides. The expected outcomes of this project will build critical components for future terahertz communication infrastructure. These antennas will support demands in point-to-point wireless ....Engineering high-efficiency all-dielectric antennas for terahertz channels. This project aims to create unconventional antenna platforms to support terahertz links. The project expects to deliver high-efficiency, high-gain dielectric resonator antennas and dielectric rod antenna arrays fed by dielectric wave-guides. The expected outcomes of this project will build critical components for future terahertz communication infrastructure. These antennas will support demands in point-to-point wireless transmission between mobile base stations, within data centres, and at information kiosks.Read moreRead less
Wideband Strongly-Truncated Composite Cavity-Resonator Antennas. A rapidly growing demand for fast wireless services calls for wideband communication systems with wideband antennas, which are compact, aesthetically appealing and inexpensive, yet have good performance. With novel concepts, this project aims to produce a new class of antennas that deliver impressive performance (bandwidth and gain) while taking up a dramatically reduced area in a way that was impossible before, increasing a figure ....Wideband Strongly-Truncated Composite Cavity-Resonator Antennas. A rapidly growing demand for fast wireless services calls for wideband communication systems with wideband antennas, which are compact, aesthetically appealing and inexpensive, yet have good performance. With novel concepts, this project aims to produce a new class of antennas that deliver impressive performance (bandwidth and gain) while taking up a dramatically reduced area in a way that was impossible before, increasing a figure-of-merit to up to seven times the state-of-the-art. Their planar geometry and simplicity lead to low cost. This is expected to create new knowledge, design methods and examples, prototypes, test results and guidelines required to design, optimise and make these versatile antennas for emerging robust broadband wireless systems.Read moreRead less
Silicon-Carbide Switches for Post-Silicon Efficiency of Power Electronics. The aim of this project is to create a prototype of a silicon carbide (SiC)-based power-electronic switch for improved energy efficiency and reduced size of power-electronic circuits, well beyond the theoretical limits of silicon technology. Until very recently, the dominant controlled switch in electronics could only be implemented as a silicon transistor. A new method of electronic passivation of SiC surfaces has enable ....Silicon-Carbide Switches for Post-Silicon Efficiency of Power Electronics. The aim of this project is to create a prototype of a silicon carbide (SiC)-based power-electronic switch for improved energy efficiency and reduced size of power-electronic circuits, well beyond the theoretical limits of silicon technology. Until very recently, the dominant controlled switch in electronics could only be implemented as a silicon transistor. A new method of electronic passivation of SiC surfaces has enabled the recent commercialisation of SiC transistors. It is expected that the material advantages of SiC can be fully exploited by a new device structure and a new fabrication process.Read moreRead less