A multidimensional model of social cognitive ageing. This project aims to develop and test a model of how normal adult ageing affects the critical ability to perceive, interpret and process social information. By using an innovative approach that integrates laboratory-based assessments with measures of real-life social behaviour, this project expects to generate novel insights into how ageing affects a range of important social cognitive skills, as well as when and why any age-related difficulti ....A multidimensional model of social cognitive ageing. This project aims to develop and test a model of how normal adult ageing affects the critical ability to perceive, interpret and process social information. By using an innovative approach that integrates laboratory-based assessments with measures of real-life social behaviour, this project expects to generate novel insights into how ageing affects a range of important social cognitive skills, as well as when and why any age-related difficulties emerge. Expected outcomes include a better understanding of the factors that drive resilience and risk for social cognitive difficulties in late adulthood, with direct implications for promoting social engagement and preventing social detachment in Australia’s growing older adult community.Read moreRead less
Testing theoretical models of age and disease related changes to inform prevention. Pathological brain changes associated with future cognitive decline become detectable in the 40s or earlier. Yet little is known about what constitutes normal brain ageing in mid-life. Using a number of neuroimaging and epidemiological techniques this project will scrutinise brain and cognitive ageing in middle-age and their significance.
The role of P2X7 and P2X4 receptor mediated innate phagocytosis in pathogenesis and treatment of neurodegenerative diseases. This project will identify how inherited variation in two proteins of the brain can accelerate the removal of neurones and predispose to a range of neurodegenerative diseases. Knowledge of the biological basis of this finding will allow a search for new compounds which will slow and protect against this form of neurodegeneration.
Why remembering together is crucial as we age. This project will test whether remembering everyday information or important past events with a long-term partner compensates for, predicts and/or reduces the risk of memory and cognitive decline. The project will identify and then target for treatment the strategies that spouses use to help each other remember, especially as they age and memory starts to fail.
Harnessing non-invasive brain stimulation to improve language function in healthy and pathological ageing. This project will examine how the ability of the ageing brain to process language can be improved by non-invasive brain stimulation. The findings have the potential to reveal new ways to treat language impairments in ageing-associated brain injury and disease.
Modelling and manipulating brain network dynamics across the lifespan. This project aims to integrate advanced computational modelling and state-of-the-art recording techniques to generate new knowledge on the neural basis of ageing. People are said to grow wiser as they grow older, though more likely they will experience cognitive slowing and reduced memory functions that interfere with their daily lives. The anticipated goal of the project is to develop techniques to predict the personalised e ....Modelling and manipulating brain network dynamics across the lifespan. This project aims to integrate advanced computational modelling and state-of-the-art recording techniques to generate new knowledge on the neural basis of ageing. People are said to grow wiser as they grow older, though more likely they will experience cognitive slowing and reduced memory functions that interfere with their daily lives. The anticipated goal of the project is to develop techniques to predict the personalised effects of brain stimulation on the ageing brain. The outcomes of this research could significantly improve understanding of brain ageing, and advance the fields of systems neuroscience, network science, and brain stimulation.Read moreRead less
The role of social-emotional learning in attaining literacy and numeracy. This project aims to characterise variability in developmental pathways to literacy and numeracy, and the factors that contribute to this variation, utilising innovative analytical approaches and population data. This project expects to generate new knowledge regarding the role of school-based social-emotional learning programs in supporting children’s achievement of literacy and numeracy. Expected outcomes of the project ....The role of social-emotional learning in attaining literacy and numeracy. This project aims to characterise variability in developmental pathways to literacy and numeracy, and the factors that contribute to this variation, utilising innovative analytical approaches and population data. This project expects to generate new knowledge regarding the role of school-based social-emotional learning programs in supporting children’s achievement of literacy and numeracy. Expected outcomes of the project include enhanced collaboration with government to deliver policy-relevant information on the most effective targets and timing for delivering social-emotional programs that maximise academic learning. This should assist policy makers to develop better strategies to support every child’s academic achievement.Read moreRead less
Understanding the contribution of neuroinflammation in acute and chronic neural injury. A major focus of this project will be investigating the involvement of neuroinflammation in neural cell damage. It will explore how neuroinflammation contributes to this damage in both acute and chronic neuropathologies.
Emerging technologies for enrichment in old age: A critical perspective. This project aims to generate knowledge about older adults' experiences with emerging technologies used for social and emotional enrichment. Technologies like virtual reality are said to offer social benefits for those in advanced old age, but we have limited knowledge about the issues that can impede older adults’ experiences with these technologies and even cause harm for vulnerable users. This project seeks to identify e ....Emerging technologies for enrichment in old age: A critical perspective. This project aims to generate knowledge about older adults' experiences with emerging technologies used for social and emotional enrichment. Technologies like virtual reality are said to offer social benefits for those in advanced old age, but we have limited knowledge about the issues that can impede older adults’ experiences with these technologies and even cause harm for vulnerable users. This project seeks to identify empirically informed strategies for good practice in the design and deployment of emerging technologies for enrichment in old age. This should inform the future ethical design and use of emerging technologies to benefit the social and emotional well-being of older Australians.Read moreRead less
The Genetic Analysis of Neurological Diseases. Multiple sclerosis and Parkinson's are debilitating neurodegenerative diseases, which affect 16,000 and 80,000 Australians, respectively. Between them, these diseases cost the community $7.8 billion per annum, and there is no cure. This proposal will study the genes that influence a person's predisposition to developing these diseases, and what makes some people have particular characteristics. It will provide novel insights into the diseases themse ....The Genetic Analysis of Neurological Diseases. Multiple sclerosis and Parkinson's are debilitating neurodegenerative diseases, which affect 16,000 and 80,000 Australians, respectively. Between them, these diseases cost the community $7.8 billion per annum, and there is no cure. This proposal will study the genes that influence a person's predisposition to developing these diseases, and what makes some people have particular characteristics. It will provide novel insights into the diseases themselves and information that could help in the development of new and more effective drugs, and biomarkers to assist in the prediction of prognosis. Such advances would decrease the economic impact of these diseases and improve quality of life for those affected.Read moreRead less