Predicting Environmental Effects on Structure and Reactivity. This project tackles one of the most important and fundamental problems in theoretical chemistry: solvent effects on chemical reactions. The new methods and computer programs generated will be freely available to the Australian (and international) scientific communitities and will further enhance Australia's strong reputation in Theoretical Chemistry.
The applications chosen will allow new technologies in biosensing and strategies in ....Predicting Environmental Effects on Structure and Reactivity. This project tackles one of the most important and fundamental problems in theoretical chemistry: solvent effects on chemical reactions. The new methods and computer programs generated will be freely available to the Australian (and international) scientific communitities and will further enhance Australia's strong reputation in Theoretical Chemistry.
The applications chosen will allow new technologies in biosensing and strategies in computational drug design to be investigated. This will benefit the Australian biotechnology and pharmaceutical industries and may substantially aid in understanding the mechanism and treatment of disease. Read moreRead less
Process Chemistry for Distributed Manufacture of Nitric Acid. This project will benefit Australia by enabling a new approach to the manufacture of explosives for the country's mining industry which will provide the entire explosives supply chain with greater safety and security. Development of this technology will enhance Orica's competitive position as the largest manufacturer of mining explosives in the world and will produce wealth for the country through the continued success of this ASX Top ....Process Chemistry for Distributed Manufacture of Nitric Acid. This project will benefit Australia by enabling a new approach to the manufacture of explosives for the country's mining industry which will provide the entire explosives supply chain with greater safety and security. Development of this technology will enhance Orica's competitive position as the largest manufacturer of mining explosives in the world and will produce wealth for the country through the continued success of this ASX Top 50 company and the export of the technology.Read moreRead less
The Role Of The Intrauterine (pro) Renin-(pro)renin Receptor System In Prostaglandin Synthesis In Pregnancy.
Funder
National Health and Medical Research Council
Funding Amount
$488,478.00
Summary
Preterm birth is associated with a very high incidence of infant disability and mortality. This has long term economic and social costs to the Australian people. We will demonstrate that in late gestation, the intrauterine (pro)renin renin receptor system controls prostaglandin synthesis by the fetal membranes and the placenta. Prostaglandins can cause premature labour.
Chemistry at the threshold: unusual mechanisms and unexpected products. The chemical processes in combustion and in the atmosphere are complex and understood incompletely; for example 30-60 million tonnes of acids in the atmosphere are unaccounted for. The project will measure and model three new chemical processes that may account for the atmospheric acids, and other unexplained occurrences in combustion chemistry.
Atmospheric photochemistry - it's a lot more complicated than we thought. The project plans to develop a more accurate model of the changing atmosphere. The chemical composition of Earth’s atmosphere is changing because of anthropogenic activities. Predicting the consequences of this change requires accurate chemical models. The hydroxyl radical (OH) is the most important radical in the atmosphere, yet atmospheric models predict its concentration in forested regions to be about 10 times lower th ....Atmospheric photochemistry - it's a lot more complicated than we thought. The project plans to develop a more accurate model of the changing atmosphere. The chemical composition of Earth’s atmosphere is changing because of anthropogenic activities. Predicting the consequences of this change requires accurate chemical models. The hydroxyl radical (OH) is the most important radical in the atmosphere, yet atmospheric models predict its concentration in forested regions to be about 10 times lower than measured. These models also predict the amount of organic acids to be lower than measured. This project hypothesises two new chemical processes to account for these discrepancies. Photo-isomerisation of carbonyls to enols is suggested to be a source of organic acids. Reaction of extraordinarily hot carbonyl photofragments with oxygen is hypothesised to be an important source of OH radicals.Read moreRead less
Centre Of Research Excellence In Medicines And Ageing
Funder
National Health and Medical Research Council
Funding Amount
$2,601,415.00
Summary
Medicines have an important place in health and are commonly used for long periods, sometimes life-long. Using medicines wisely requires a careful balance between benefits and harmful effects. Currently, there is limited information to guide medicines use over a lifetime. Using large linked datasets, the CRE in Medicines and Ageing will generate much needed evidence about real world medicines use to support clinical and pharmaceutical policy decisions.
Molecular signatures of complex photodissociation reactions. All energy on earth comes from the sun, either directly (e.g photosynthesis) or indirectly (e.g fossil fuels). Photochemistry is the study of how this light is absorbed and what happens to a molecule afterwards. Despite significant experimental and theoretical advances in the past decade (some in our lab), scientists still cannot predict the outcomes of most photochemical reactions. In this project we will determine the reactivity o ....Molecular signatures of complex photodissociation reactions. All energy on earth comes from the sun, either directly (e.g photosynthesis) or indirectly (e.g fossil fuels). Photochemistry is the study of how this light is absorbed and what happens to a molecule afterwards. Despite significant experimental and theoretical advances in the past decade (some in our lab), scientists still cannot predict the outcomes of most photochemical reactions. In this project we will determine the reactivity of several small, fundamental organic molecules. Not only are these molecules pollutants around our cities, but discovery of how they react in the presence of light will allow us to understand and predict the photochemistry of a much wider range of organic species.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100365
Funder
Australian Research Council
Funding Amount
$462,237.00
Summary
Solar-driven catalytic production of high-value product from waste glycerol. Sustainable bio-refining requires an efficient and economical way of utilising the surplus amount of glycerol generated as a by-product in biodiesel industries. This project aims to construct an industry-scale solar-driven catalytic system to generate high-value-added chemicals and green hydrogen fuel from biomass wastes simultaneously. The structure-reactivity relationship of working catalysts will be established to fi ....Solar-driven catalytic production of high-value product from waste glycerol. Sustainable bio-refining requires an efficient and economical way of utilising the surplus amount of glycerol generated as a by-product in biodiesel industries. This project aims to construct an industry-scale solar-driven catalytic system to generate high-value-added chemicals and green hydrogen fuel from biomass wastes simultaneously. The structure-reactivity relationship of working catalysts will be established to fit the up-scale applications. The gained cutting-edge knowledge and technology will significantly contribute to biomass waste utilisation and sustainable fabrication, further bringing significant economic and social benefits by creating a new competitive business for Australian chemical and fuel areas. Read moreRead less