Using Lessons From The United Kingdom To Improve The Reproductive Health Of Aboriginal Adolescent Women
Funder
National Health and Medical Research Council
Funding Amount
$419,768.00
Summary
I will examine if parity and pre and post natal exercise can prevent urinary incontinence among older women in a large cohort study in the United Kingdom and use these skills to examine the contraceptive use of Aboriginal adolescent females and influence pre and post natal programs in four Aboriginal communities. The more knowledge and support Aboriginal adolescent females have the higher chances of them making informed decisions about their reproductive health.
Building The Evidence Base To Match Health Action To Need For Adolescents Globally
Funder
National Health and Medical Research Council
Funding Amount
$348,768.00
Summary
This fellowship involves 3 inter-related bodies of work focussing on adolescent health. Firstly, I will use existing data to better describe the health needs of adolescents living in the Asia-Pacific region, with a focus on Aboriginal and Torres Strait Islander adolescents. Secondly, I will identify priority areas for better data collection and explore novel methods to fill key gaps. Thirdly, I will investigate how the described health profiles can be translated into health action.
Prevalence Of Challenge-proven Food Allergy And Predictors Of Severe Adverse Reactions To Food In Early Adolescence: SchoolNuts
Funder
National Health and Medical Research Council
Funding Amount
$1,196,852.00
Summary
Food allergy (FA) has risen to epidemic proportions in recent times and Australia has one of the highest rates in the world. FA is most common in children under 5 years, yet adolescents are at the greatest risk of death from food-related anaphylaxis. We don’t know why this is the case. Our research will describe FA prevalence and will assess the factors placing FA adolescents at high risk of severe allergic reactions. Findings will influence policy for management of FA and anaphylaxis.
Characterising Disease Burden In Youth: A Systematic Analysis Of Global Data
Funder
National Health and Medical Research Council
Funding Amount
$137,700.00
Summary
I am a paediatric trainee who has worked with young people in a variety of settings. I have also completed training in epidemiology. My project will use the Global Burden of Disease study to estimate rates of death, disease, injury and risk factors for young people on a global scale. It will extend the burden of disease framework to better understand Indigenous young people’s health in Australia, and will critically review the best ways to measure the health of young Indigenous people.
Investigating The Relationships Between Cannabis And Other Drug Use, Mental Health, Early-life Factors And Life-course Outcomes: Integrative Analyses Of Data From Four Australasian Cohort Studies
Funder
National Health and Medical Research Council
Funding Amount
$292,097.00
Summary
The current study will be the first of its kind to use integrative data analyses _ a highly innovative approach _ to pool data from four large and long-running Australasian cohort studies to better understand the link between cannabis use and later-life outcomes. Dramatically improved knowledge of these relationships will create a clearer picture of the interventions required to reduce the harms associated with cannabis use.
The RADAR Project: Identifying Early Warning Signals On The Pathways To Alcohol Use Disorder
Funder
National Health and Medical Research Council
Funding Amount
$884,321.00
Summary
The transition from alcohol initiation to an alcohol use disorder is a crucial yet under-studied research area. The current project will characterise the natural history of alcohol use disorder and identify modifiable factors that increase or decrease the likelihood of developing an alcohol use disorder once alcohol use begins. This information will guide prevention of, and early intervention for, this disabling disorder.
Socioeconomic Variation In Community Risk Profiles Associated With Health And Behaviour Problems In Adolescents
Funder
National Health and Medical Research Council
Funding Amount
$459,700.00
Summary
Until recently, emotional and behavioural problems of adolescence have tended to be dismissed as part of the normal turbulence of adolescent development; however, attitudes to adolescent health and health promotion have changed quickly. Downward age-trends in tobacco, alcohol and illicit drug use have made adolescents a major target for health promotion. The practical potential for adolescent mental health promotion has gained considerable ground and knowledge of the modifiable determinants of y ....Until recently, emotional and behavioural problems of adolescence have tended to be dismissed as part of the normal turbulence of adolescent development; however, attitudes to adolescent health and health promotion have changed quickly. Downward age-trends in tobacco, alcohol and illicit drug use have made adolescents a major target for health promotion. The practical potential for adolescent mental health promotion has gained considerable ground and knowledge of the modifiable determinants of youth mental health problems has been progressed by a growing number of studies examining distal and proximal predictors in community samples. The project plans to comprehensively assess locally elevated risk factors and depressed protective factors predictive of a range of adolescent health and behaviour problems including substance abuse, obesity and depression in 30 communities across three Australian States. These communities will be selected from the entire socioeconomic spectrum to determine how the social context of our neighbourhoods may influence the health and behaviour of adolescents . Surveys of students in grade 6 and year 8 will be conducted. Each participating student will be weighed and measured and asked to complete a questionnaire that assesses a comprehensive range of community risk and protective factors.Read moreRead less
Early Life Stress, Adolescent Brain Development And Risk For Adverse Cognitive And Psychosocial Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$640,595.00
Summary
This project aims to study pre and postnatal childhood factors and examine their association with HPA-functioning, cognition, and mental health during adolescence in the Western Australian Pregnancy Cohort Study (Raine Study). Childhood exposures include not only trajectories of stressful life events, family functioning and mental health status during childhood, but also effects of intrauterine and postnatal growth patterns, and a comprehensive range of psychosocial, familial and environmental f ....This project aims to study pre and postnatal childhood factors and examine their association with HPA-functioning, cognition, and mental health during adolescence in the Western Australian Pregnancy Cohort Study (Raine Study). Childhood exposures include not only trajectories of stressful life events, family functioning and mental health status during childhood, but also effects of intrauterine and postnatal growth patterns, and a comprehensive range of psychosocial, familial and environmental factors. It is our objective to characterise functional polymorphisms for genes related to stress regulation and examine their interactions with early life exposures and their neurobiological consequences. We will also test 16 year old Raine subjects for cognitive ability, and in some we will image their brain activity while performing these tests. We anticipate to enhance the already comprehensive phenotypic Raine Study data base with neurobiological information for future neuroscience studies as the Raine cohort matures. We hypothesise that increased and sustained trajectories of early life stress, family dysfunction or poor mental health during childhood will increase the risk of Raine Study adolescents experiencing: (i) - increased stress sensitivity with higher baseline cortisol levels during adolescence; (ii) - increased adolescent stress sensitivity, if they are carriers of specific haplotypes of the glucocorticoid and mineralocorticoid receptor genes.;(iii) - depression during adolescence, if they are homozygous or heterozygous for the short allele of the serotonin transporter (5-HTT) gene; (iv) - poorer cognitive performance and increased atypical non-prefrontal cortex (PFC) brain activity during cognitive testing as measured by fMRI; and (v) -more mental health problems during adolescence.Read moreRead less
Young Adult Social Transitions - Course Of Mental And Behavioural Disorders:The Victorian Adolescent Health Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$560,750.00
Summary
The paths young people follow into adulthood have changed markedly in the past three decades. Traditionally the adoption of a role as marital partner, parent and fulltime employee in the late teens and early twenties was accompanied by a diminution or 'maturing out' of health risk behaviours and emotional problems arising in adolescence. The social transitions into adulthood are now both delayed and in many instances changed with higher rates of cohabitation, extended teriary educational partici ....The paths young people follow into adulthood have changed markedly in the past three decades. Traditionally the adoption of a role as marital partner, parent and fulltime employee in the late teens and early twenties was accompanied by a diminution or 'maturing out' of health risk behaviours and emotional problems arising in adolescence. The social transitions into adulthood are now both delayed and in many instances changed with higher rates of cohabitation, extended teriary educational participation and part-time employment. The effect of these social changes on health risk behaviours, behavioural and mental disorders is uncertain. This proposal will undertake a further follow-up in the late twenties of a group of just under 2000 young Victorians, already studied from the age of 14 years through to the age of 24 years. This study will assess the persistence of behavioural problems such as smoking and nicotine dependence, excessive alcohol consumption and dependence, cannabis dependence, illicit drug use, risk sexual behaviour, depression and anxiety disorders. The extent to which these may be associated with successful negotiation of transitions in education, employment, relationships, parenthood and establishing an independent home will be evaluated. Alternative explanations including the severity of dependence syndrome, personality, social background and genetic risk factors will also be explored.Read moreRead less