Experimental Demonstrations of New Theorems of Nonequilibrium Thermodynamics. In the last decade, two theorems have been proposed to revolutionise the field of thermodynamics. These theorems lift the restriction of the thermodynamic limit, allowing thermodynamic concepts to be applied to small systems such as nanomachines, and characterise systems that may be far-from-equilibrium. These theorems are at odds with a traditional understanding of 19th century thermodynamics where equilibrium is cent ....Experimental Demonstrations of New Theorems of Nonequilibrium Thermodynamics. In the last decade, two theorems have been proposed to revolutionise the field of thermodynamics. These theorems lift the restriction of the thermodynamic limit, allowing thermodynamic concepts to be applied to small systems such as nanomachines, and characterise systems that may be far-from-equilibrium. These theorems are at odds with a traditional understanding of 19th century thermodynamics where equilibrium is central and the Second Law inviolate. However they are critical to the application of thermodynamic concepts to modern systems of the 21st century. Using Optical Tweezers, we will experimentally demonstrate these theorems, present irrefutable evidence of their validity, and demonstrate their application in modern systems.Read moreRead less
Experimental Demonstrations of Violations of the Second Law of Thermodynamics. Inventors and engineers strive to scale-down machines, devices and engines to nanometre sizes for a range of technological purposes and scientists investigate protein motors to understand their operation in hopes of modifying their biological behaviour. However, according to a new theorem in Non-equilibrium Statistical Mechanics, there is a fundamental limit to this scaling-down of engines: such nanomachines, includi ....Experimental Demonstrations of Violations of the Second Law of Thermodynamics. Inventors and engineers strive to scale-down machines, devices and engines to nanometre sizes for a range of technological purposes and scientists investigate protein motors to understand their operation in hopes of modifying their biological behaviour. However, according to a new theorem in Non-equilibrium Statistical Mechanics, there is a fundamental limit to this scaling-down of engines: such nanomachines, including protein motors, will run in "reverse" for appreciable amounts of time and in violation of the Second Law of Thermodynamics. We propose to demonstrate this inescapable, operational limit in nanotechnology with experiments using an Optical Tweezers apparatus.Read moreRead less
Synthesis and Analysis of Canine Anabolic Steroid Metabolites. The Australian racing industry is a major driver of economic activity. In NSW, racing is estimated to contribute $1,000 million to GDP, $151 million to Government revenue and provide 50,000 jobs. The future security and prosperity of the racing industry depends on maintaining the highest standards of integrity in the public eye, and this in turn depends on the enforcement of regulations relating to illicit substances. The outcome of ....Synthesis and Analysis of Canine Anabolic Steroid Metabolites. The Australian racing industry is a major driver of economic activity. In NSW, racing is estimated to contribute $1,000 million to GDP, $151 million to Government revenue and provide 50,000 jobs. The future security and prosperity of the racing industry depends on maintaining the highest standards of integrity in the public eye, and this in turn depends on the enforcement of regulations relating to illicit substances. The outcome of this project will be the introduction of robust methods of analysis for potential drug abuse in greyhound racing that will position Australia as a world leader in the field.Read moreRead less
Nanotribology-The Chemical Rolling Resistance of Single Nanocrystals. Australian efforts in biosensors, environmental monitoring and mobile-health are predicated on the establishment of a nanotechnology based manufacturing sector. The key to this will be understanding how ultrasmall mechanical devices work. This application explores how we can make novel mechanical devices from molecules and small crystals.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882357
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
A Computational Facility for Multi-scale Modelling in Bio and Nanotechnology. Bio- and nanotechnology have the potential to transform Australian industry and research, and to bring significant benefits for consumers. The scope will include materials for energy storage, medical diagnostics and cellular imaging, bioengineering, drug and gene delivery, improved foods by molecular design, novel materials for electronics, improved techniques for particle processing, and molecular sieves for filtering ....A Computational Facility for Multi-scale Modelling in Bio and Nanotechnology. Bio- and nanotechnology have the potential to transform Australian industry and research, and to bring significant benefits for consumers. The scope will include materials for energy storage, medical diagnostics and cellular imaging, bioengineering, drug and gene delivery, improved foods by molecular design, novel materials for electronics, improved techniques for particle processing, and molecular sieves for filtering/purifying water and gases. The dedicated computing facility will enable a fast interactive cycle between simulation and experiment in these areas, accelerating the pace of research and applications.Read moreRead less
Energy Conversion and Signal Transduction in Nanomechanical Systems. Miniaturization of materials and electronic devices is an important technological goal. In order to make smaller working devices,we need to understand how to create molecular scale devices such as valves, switches, pumps and motors. This Fellowship will explore ways to make smaller, portable devices that can be used for personal health monitoring,environmental sensing and the detection of disease and pathogens.
Disorder and Dynamics in Superionic Conductors. This project will pursue a powerful new approach to superionic conductors, an important class of advanced materials that are critical to the development of clean-energy technologies, such as solid-oxide fuel cells. This will be a new direction for Australian science in the theoretical treatment of material properties. The project will also make significant progress in the computer-aided design of advanced materials, and in the simulation methods th ....Disorder and Dynamics in Superionic Conductors. This project will pursue a powerful new approach to superionic conductors, an important class of advanced materials that are critical to the development of clean-energy technologies, such as solid-oxide fuel cells. This will be a new direction for Australian science in the theoretical treatment of material properties. The project will also make significant progress in the computer-aided design of advanced materials, and in the simulation methods themselves, contributing to pure science in the form of our understanding of the physics and chemistry of materials at the most fundamental level. Read moreRead less
The First Chemically Accurate Tools in Theoretical Materials Research. Non-metallic materials are widely used in catalytic, separation and sensing applications. This project will create a new, accurate, general and systematic approach to the computational study of non-metallic materials and will provide an enormous step forward in our ability to design these materials for specific applications. With ever increasing demand, growing world population and shrinking natural resources, the benefits of ....The First Chemically Accurate Tools in Theoretical Materials Research. Non-metallic materials are widely used in catalytic, separation and sensing applications. This project will create a new, accurate, general and systematic approach to the computational study of non-metallic materials and will provide an enormous step forward in our ability to design these materials for specific applications. With ever increasing demand, growing world population and shrinking natural resources, the benefits of such rational materials design impact on the development of new, safer, more efficient, reusable materials in chemical, engineering, electronic and biological applications. Read moreRead less
Special Research Initiatives - Grant ID: SR0354636
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecula ....Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecular scale computations in the fields of nanoscience, biomaterials, biotechnology, biomedical science and environmental science. It will uncover and explore critical new interdisciplinary science and create new molecular-based paradigms that will drive advances in these fields over the next decade.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237958
Funder
Australian Research Council
Funding Amount
$133,000.00
Summary
An enclosive flow Cooling cell for spectroscopic studies. We wish to install a low temperature absorption cell that will be coupled to high resolution spectrometer systems operating in the infrared, visible and ultra-violet regions of the spectrum. This will enable us to further develop techniques for the study of the structures, dynamics and kinetics of molecules of biological and atmospheric significance. This will lead to a better understanding of the structures, dynamics and reaction kinetic ....An enclosive flow Cooling cell for spectroscopic studies. We wish to install a low temperature absorption cell that will be coupled to high resolution spectrometer systems operating in the infrared, visible and ultra-violet regions of the spectrum. This will enable us to further develop techniques for the study of the structures, dynamics and kinetics of molecules of biological and atmospheric significance. This will lead to a better understanding of the structures, dynamics and reaction kinetics of these species and in the case of atmospheric species also provide molecular parameters required for atmospheric monitoring.Read moreRead less