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Evidence-based Physical Activity Promotion In Primary Schools: Improving Children’s Health Through Sustainable Partnerships
Funder
National Health and Medical Research Council
Funding Amount
$1,299,824.00
Summary
Physical inactivity is a leading cause of disease in Australia. Working with the NSW Department of Education, this project aims to increase children’s activity and improve their health. Involving 200 primary schools, we will examine teachers’ adoption of the program and its impact on children’s fitness, well-being and academic performance. The project will provide the evidence and framework for the Department to promote physical activity throughout NSW and a model for adoption in other states.
The Central Australian Heart Protection Study: A Randomised Trial Of Nurse-Led, Family Based Secondary Prevention Of Acute Coronary Syndromes
Funder
National Health and Medical Research Council
Funding Amount
$1,923,630.00
Summary
Despite the high burden of cardiovascular diseases among Indigenous Australians, few intervention trials have sought to evaluate novel approaches to reducing differential outcomes in this vulnerable group. The Central Australian Heart Protection Study seeks to test the effectiveness of a nurse-led, family based education and assessment program in reducing the incidence of poor outcomes in indigenous and non-indigenous patient’s following an Acute Coronary Syndrome (ACS).
Enhancing Peripheral Clearance Of Beta Amyloid As A Treatment For Alzheimers Disease
Funder
National Health and Medical Research Council
Funding Amount
$548,681.00
Summary
Amyloid-beta (abeta) accumulation in the brain is a key step in the development of Alzheimer's disease, with potential therapies focusing on its clearance. Compounds that bind abeta in blood have been shown to alter brain abeta levels. We will assess the efficacy of a novel abeta-binding peptide to promote peripheral clearance of brain-derived abeta in a mouse model of AD. Such a drug would be effective in sporadic AD, where the efflux transport, clearance and degradation systems are defective.