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The Consequences Of Innate Anti-viral Effector Responses On Reproductive Outcomes In Placental Mammals
Funder
National Health and Medical Research Council
Funding Amount
$328,060.00
Summary
The mother's immune system can tolerate the growth of an ostensibly foreign fetus during pregnancy. We will investigate whether exposure to viral infections either just before or during pregnancy can result in reduced fertility and whether it may affect fetal growth and development. These results will contribute in designing effective interventions to limit any potential detrimental outcomes.
The Consequences Of Innate Immune Inflammatory Responses During Early Pregnancy And Their Effect On Reproductive Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$367,788.00
Summary
The mother's immune system can tolerate the growth of an ostensibly foreign fetus during pregnancy, yet remain vigilant to pathogenic challenge. We will investigate whether exposure to viral infections during early pregnancy leads to maternal and fetal inflammation which then impacts adversely on reproductive outcomes including fetal development and life-long health of offspring. Answers to these questions will contribute in designing effective interventions to limit the potential for detrimenta ....The mother's immune system can tolerate the growth of an ostensibly foreign fetus during pregnancy, yet remain vigilant to pathogenic challenge. We will investigate whether exposure to viral infections during early pregnancy leads to maternal and fetal inflammation which then impacts adversely on reproductive outcomes including fetal development and life-long health of offspring. Answers to these questions will contribute in designing effective interventions to limit the potential for detrimental outcomes.Read moreRead less