Synthesis of nanoparticles by impinging liquid-jet precipitation for inhalation drug delivery. The project aim is to develop a state of the art technology for the efficient, reliable and economical production of nanoparticles of drugs suitable for inhalation delivery to the lung. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. The project will focus on both the production process and the particle properties for aerosol a ....Synthesis of nanoparticles by impinging liquid-jet precipitation for inhalation drug delivery. The project aim is to develop a state of the art technology for the efficient, reliable and economical production of nanoparticles of drugs suitable for inhalation delivery to the lung. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. The project will focus on both the production process and the particle properties for aerosol administration. Successful development of the technology will not only gain new knowledge in the key area of nanotechnology, but also lead to better inhalation therapy to benefit patients.Read moreRead less
Development of a novel process for the formation of particles with controlled surface architecture for respiratory drug delivery. A successful conclusion of this project will enhance substantially the competitiveness of Australia's research in functional nanomaterials and advanced biomaterials. The Australian pharmaceutical industry will gain through the ability to develop proprietary pharmaceutical formulations targeted towards taking advantage of the novel process. Patients of asthma, lung inf ....Development of a novel process for the formation of particles with controlled surface architecture for respiratory drug delivery. A successful conclusion of this project will enhance substantially the competitiveness of Australia's research in functional nanomaterials and advanced biomaterials. The Australian pharmaceutical industry will gain through the ability to develop proprietary pharmaceutical formulations targeted towards taking advantage of the novel process. Patients of asthma, lung infection and other serious health problems will benefit from an improved delivery of therapeutic dose at a much reduced cost. The technology is environmentally friendly as powder aerosol delivery does not require any harmful organic solvent to operate.Read moreRead less
High Gravity Precipitation of Nanoparticles for Pulmonary Drug Delivery. This collaborative project aims to explore the huge market potential of drug delivery by inhalation aerosols using nanoparticles. It will apply cutting edge nanotechnology to develop new techniques using high gravity to synthesise particles of biomaterials suitable for inhalation. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. Successful developme ....High Gravity Precipitation of Nanoparticles for Pulmonary Drug Delivery. This collaborative project aims to explore the huge market potential of drug delivery by inhalation aerosols using nanoparticles. It will apply cutting edge nanotechnology to develop new techniques using high gravity to synthesise particles of biomaterials suitable for inhalation. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. Successful development of the technology will position both Australia and the industry partner to take a lead in the application of this novel technology in pharmaceutical aerosols, and provides better inhalation therapy to benefit patients.Read moreRead less
The Scale-up and Evaluation of a Novel Dense Gas Technology Platform for the Production of Particles for Aerosol Drug Delivery. This project provides a unique opportunity to develop an Australian-invented technology in particle engineering, enabling it to enter the international pharmaceutical market. This will enhance the growth of Australia's pharmaceutical research and development, and benefit the Australian pharmaceutical industry. The outcome will also contribute to improvements in the heal ....The Scale-up and Evaluation of a Novel Dense Gas Technology Platform for the Production of Particles for Aerosol Drug Delivery. This project provides a unique opportunity to develop an Australian-invented technology in particle engineering, enabling it to enter the international pharmaceutical market. This will enhance the growth of Australia's pharmaceutical research and development, and benefit the Australian pharmaceutical industry. The outcome will also contribute to improvements in the health and well-being of Australians. The research falls within the Designated National Research Priority of Frontier Technologies for Building and Transforming Australian Industries.Read moreRead less
Dispersion of Pharmaceutical Powders as Aerosols for Inhalation. The detrimental environmental effects of chlorofluorocarbons (CFC) have led to an urgent need of a replacement for the existing CFC propellant driven medical inhalers. Generation of aerosols from dry powders has enormous potential as an alternative for delivery of drugs to the lung. The aims of the proposed research are to investigate specifically the powder surface properties and the orperating conditions on the dispersion of po ....Dispersion of Pharmaceutical Powders as Aerosols for Inhalation. The detrimental environmental effects of chlorofluorocarbons (CFC) have led to an urgent need of a replacement for the existing CFC propellant driven medical inhalers. Generation of aerosols from dry powders has enormous potential as an alternative for delivery of drugs to the lung. The aims of the proposed research are to investigate specifically the powder surface properties and the orperating conditions on the dispersion of powders as aerosols for inhalation. The knowledge gained will acclerate the design of better powder aerosols, thus benefiting patients suffering from respiratory and systemic diseases.Read moreRead less
Mannitol Powders for Assessment of Asthma in Children. A successful conclusion of this project will enable Australia to become a world leader in childhood asthma assessment. The availability of an objective diagnostic test for early detection of asthma would assist formulating early treatment strategies at this crucial stage in the progression of the disease, improving the quality of life of asthma sufferers in their early years. The Australian pharmaceutical sector will benefit through the ab ....Mannitol Powders for Assessment of Asthma in Children. A successful conclusion of this project will enable Australia to become a world leader in childhood asthma assessment. The availability of an objective diagnostic test for early detection of asthma would assist formulating early treatment strategies at this crucial stage in the progression of the disease, improving the quality of life of asthma sufferers in their early years. The Australian pharmaceutical sector will benefit through the ability to develop proprietary formulations targeted towards taking advantages of the scientific knowledge on pharmaceutical powders and aerosols. The mannitol testing is environmental friendly as powder aerosol delivery does not require any harmful organic solvents to operate.Read moreRead less