Optimising bubble continuous positive airway pressure (CPAP) for preterm infants. Synchrotron imaging will be used to see how the lungs of newborns are aerated and move when they are supported by continuous positive airway pressure (CPAP) breathing support. This project will provide fundamental biological information that will contribute to refinement of devices to support breathing in babies.
Pontine control of adaptive breathing behaviour in health and disease. This project will develop an understanding of the fundamental brain mechanisms associated with adaptive breathing during behaviour such as speech or swallowing. Adaptive breathing is impaired in lung disease, dementia and autism. This project will provide new insight to global brain function and treatment of central respiratory disorder.