Understanding how bacteria form multicellular biofilm communities on surfaces: the role of cyclic diguanylate as a potent biofilm activator. Bacteria usually exist as multicellular communities called biofilms when attached to surfaces, frequently to the detriment of the environment, industry and health. This project will explore the strategies bacteria use to switch from living as free-floating, individual cells to forming biofilms by studying how bacteria 'switch on' their biofilm genes.
Improved electrophoretic analyser for water quality monitoring. This proposal will advance the Australian made Eco Detection portable electrophoretic analyser for autonomous monitoring of water chemistry - the Eco Sensor. We will re-design and miniaturise the fluidic manifold to reduce capital- and per-sample cost, increase the sensitivity of nutrients - nitrate and phospate - by 100-times in both fresh- and sea-waters, and develop new ultra-sensitive reagents for heavy metal detection at enviro ....Improved electrophoretic analyser for water quality monitoring. This proposal will advance the Australian made Eco Detection portable electrophoretic analyser for autonomous monitoring of water chemistry - the Eco Sensor. We will re-design and miniaturise the fluidic manifold to reduce capital- and per-sample cost, increase the sensitivity of nutrients - nitrate and phospate - by 100-times in both fresh- and sea-waters, and develop new ultra-sensitive reagents for heavy metal detection at environmentally regulated levels. This will provide a single platform for at-site near-real-time monitoring of water chemistry for agricultural, mining, water corporations and other industries that use and/or discharge water to the environment. Read moreRead less
Predictive Models And Interventions For Coronary Heart Disease In Aboriginal And Torres Strait Islander People
Funder
National Health and Medical Research Council
Funding Amount
$203,125.00
Summary
The main causes of heart disease in western countries are smoking, high blood pressure and high cholesterol. However, in indigenous populations, other factors may be more important. We propose to look at these conventional risk factors and others like diabetes, blood clotting disorders and inflammation to see which are best for predicting heart attack in Aboriginal and Torres Strait Islander people . We will also examine the effect of heart disease prevention programs run by communities, to see ....The main causes of heart disease in western countries are smoking, high blood pressure and high cholesterol. However, in indigenous populations, other factors may be more important. We propose to look at these conventional risk factors and others like diabetes, blood clotting disorders and inflammation to see which are best for predicting heart attack in Aboriginal and Torres Strait Islander people . We will also examine the effect of heart disease prevention programs run by communities, to see if they can improve these risk factors. Finally, we will use this information to produce educational materials and clinical tools for health services.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100441
Funder
Australian Research Council
Funding Amount
$474,443.00
Summary
Sounds of change: using ecological knowledge to advance acoustic monitoring. To recover biodiversity, conservation actions must be informed by robust ecological data. In partnership with Bush Heritage Australia, this project aims to transform ecological monitoring with eco-acoustic technologies by developing new acoustic metrics to measure biodiversity at various levels, from individual species through to whole communities. This project will combine advanced computer methods with theories of ani ....Sounds of change: using ecological knowledge to advance acoustic monitoring. To recover biodiversity, conservation actions must be informed by robust ecological data. In partnership with Bush Heritage Australia, this project aims to transform ecological monitoring with eco-acoustic technologies by developing new acoustic metrics to measure biodiversity at various levels, from individual species through to whole communities. This project will combine advanced computer methods with theories of animal sounds and communities to generate metrics that are informed by animal ecology and directly address monitoring needs of conservation organisations. By experimentally testing the metrics on long-duration real-world sound data, this project will provide new tools to measure conservation impact and prioritise actions.Read moreRead less
Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of th ....Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of this complex inverse estuary system and its surrounding catchment. The new understanding of the sources, fluxes and fate of nutrients within the bay and the surrounding catchment, arising from this project, is expected to benefit management decision-making and establish a new standard in estuarine water quality investigation.Read moreRead less
Development And Validation Of The First Culturally Based Quality Of Life Tool For Aboriginal Australians Living With Dementia Or Cognitive Impairment
Funder
National Health and Medical Research Council
Funding Amount
$602,435.00
Summary
Enhancing quality of life (QoL) is the central goal of care providers for clients with dementia. A QoL tool identifies areas of need, enabling strategies to be planned and evaluated accordingly. Dementia is highly prevalent in Aboriginal Australians. There is no QoL tool for Aboriginal Australians living with dementia. This project will develop and test a QoL tool with Aboriginal Australians living with dementia or other cognitive impairment. The factors affecting QoL will also be identified.
eGenomics - Next generation biomonitoring of threatened species. DNA is the molecule of life and exists everywhere in the environment as a largely untapped source of information on evolution, biodiversity, and ecosystem health. Our overriding aim is to start mining that information to benefit threatened species. Based on optimized ancient DNA methods, powerful sequencing technology, whole genome analyses, and RNA profiling, we present a novel and holistic framework for genetic biomonitoring. In ....eGenomics - Next generation biomonitoring of threatened species. DNA is the molecule of life and exists everywhere in the environment as a largely untapped source of information on evolution, biodiversity, and ecosystem health. Our overriding aim is to start mining that information to benefit threatened species. Based on optimized ancient DNA methods, powerful sequencing technology, whole genome analyses, and RNA profiling, we present a novel and holistic framework for genetic biomonitoring. In two parallel model systems we will study corals and reptiles to improve environmental detection while simultaneously obtaining information on their population health. This will foster more efficient conservation of endangered species that are of tremendous importance to our marine and terrestrial ecosystems.Read moreRead less
From Advocacy To Action: Utilising Health Impact Assessment As A Tool To Realise The Right To Health.
Funder
National Health and Medical Research Council
Funding Amount
$97,419.00
Summary
The actions of governments often affect people’s health and wellbeing. Health Impact Assessment (HIA) is used to identify how these actions may impact on health and develop recommendations about how to maximise positive health benefits and reduce or stop negative impacts. This project is investigating how human rights can be used to strengthen the role of HIA in protecting the right to health.
Epidemiology, Costs And Clinical Outcomes Of Inflammatory Bowel Disease In Victoria
Funder
National Health and Medical Research Council
Funding Amount
$66,881.00
Summary
The inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are chronic inflammatory disorders of the gastrointestinal tract. The number of people in Australia with these conditions is unknown and the impact of illness is also poorly defined. This research aims to establish the number of people developing these conditions in a region of Australia. In addition the impact in terms of personal and health economic costs, quality of life and psychological effect will be determined.