Chronic pain and functional impairment following traumatic injury: an investigation into the impact of compensation status and experience. This project will enhance understanding of the impact of the psychosocial factors and the compensation process on recovery from traumatic injury. The project will generate new resources (screening and referral guidelines; educational materials) to improve decision making consistency, client experience, and recovery from road trauma.
Improving Neurobehavioural Development In Preterm Infants: A Randomised Controlled Trial Of A Neonatal Intervention
Funder
National Health and Medical Research Council
Funding Amount
$680,920.00
Summary
Up to 50% of preterm infants will have one or more developmental difficulties. While medical complications are implicated in these problems, recent evidence points to the added effect of the infant's early environment. Hospitalised premature infants experience stress from necessary but painful hospital procedures, overstimulation and maternal deprivation. Evidence, largely from animal studies, suggests stressful early experience negatively affects brain development. We also know that premature i ....Up to 50% of preterm infants will have one or more developmental difficulties. While medical complications are implicated in these problems, recent evidence points to the added effect of the infant's early environment. Hospitalised premature infants experience stress from necessary but painful hospital procedures, overstimulation and maternal deprivation. Evidence, largely from animal studies, suggests stressful early experience negatively affects brain development. We also know that premature infants find it difficult to handle stress as they are highly disorganised neurobehaviourally. The primary aim of this study is to assess the effectiveness of a parent-based intervention in enhancing neurobehavioural development at two years of age in very premature infants. It is predicted that this stress-reduction intervention will also enhance medical stability,normal brain development, parent-child interaction and parental mental health. The intervention to be trialled involves intensive training of parents of very premature infants, and in the 12 weeks following birth the parents will be the change agents. A randomised controlled trial comparing intervention and control groups will be undertaken to assess the effectiveness of this intervention. Assessments of early brain and 2 year intellectual, emotional and behavioural development will provide important outcome measures. A major strength of this study is the inclusion of advanced Magnetic Resonance Imaging (MRI) technology as it enables differences in brain development between the intervention and control group to be assessed, the association between brain and neurobehavioural development to be explored, and the impact of stress on early brain development to be investigated. This intervention is relatively simple and inexpensive, and would be a valuable contribution to neonatal care if found to be effective in enhancing brain and neurobehavioural development.Read moreRead less
The role of attention re-training in pain tolerance. Chronic pain is one of the most debilitating and expensive chronic health problems in westernized countries. Chronic pain develops when an individual is injured and is fearful of the pain that they experience. This causes them to become hypervigilant to pain, avoid activity and results in a vicious cycle of increasing disability. This research has two, related aims. First, we aim to test this model to see whether hypervigilance influences resp ....The role of attention re-training in pain tolerance. Chronic pain is one of the most debilitating and expensive chronic health problems in westernized countries. Chronic pain develops when an individual is injured and is fearful of the pain that they experience. This causes them to become hypervigilant to pain, avoid activity and results in a vicious cycle of increasing disability. This research has two, related aims. First, we aim to test this model to see whether hypervigilance influences response to pain, as predicted. Second, we will develop and test an intervention to reduce hypervigilance to pain in healthy people and those with acute injuries. If the intervention is successful, it will have the potential to prevent the development of chronic pain or reduce its severity.Read moreRead less
Motherhood choices: a decision aid for women with rheumatoid arthritis. Decisions about pregnancy in the context of debilitating rheumatoid arthritis impact directly on both the mother and the child as well as their family and wider social unit. Providing evidence-based information to support women in making informed decisions about motherhood is critical in maximizing the well-being of the mother and ensuring a healthy start to life for a baby. The project will contribute to the national resear ....Motherhood choices: a decision aid for women with rheumatoid arthritis. Decisions about pregnancy in the context of debilitating rheumatoid arthritis impact directly on both the mother and the child as well as their family and wider social unit. Providing evidence-based information to support women in making informed decisions about motherhood is critical in maximizing the well-being of the mother and ensuring a healthy start to life for a baby. The project will contribute to the national research priority area of promoting and maintaining good health, addressing the goal of supporting a healthy start to life.Read moreRead less
Suicide prevention and management of deliberate self-harm: randomised control trial of an assertive engagement, brief psychotherapy and community linkage model. Suicide is the second commonest cause of death by injury in Australia. Suicide prevention is an important public health priority but rates remain high. People who have previously attempted suicide are most likely to kill themselves. Most suicidal people attend emergency departments where they get inadequate treatment for their psychologi ....Suicide prevention and management of deliberate self-harm: randomised control trial of an assertive engagement, brief psychotherapy and community linkage model. Suicide is the second commonest cause of death by injury in Australia. Suicide prevention is an important public health priority but rates remain high. People who have previously attempted suicide are most likely to kill themselves. Most suicidal people attend emergency departments where they get inadequate treatment for their psychological and social problems and remain depressed and suicidal. This project will test the effectiveness of a new psychological and social treatment to reduce the depression and link suicidal people with community supports. If successful, this treatment could be provided in any emergency department and help decrease suicide rates in Australia.Read moreRead less
Discovery Indigenous Researchers Development - Grant ID: DI110100034
Funder
Australian Research Council
Funding Amount
$300,401.00
Summary
Measurement matters: analysis of potential methodological and discrimination biases in assessments of medication treatments for ADHD, and stakeholder views. This research aims to identify multiple stakeholders' views of the nature of Attention Deficit Hyperactivity Disorder and test if discrimination and survey wording result in bias when assessing the impact of medical treatments. This will result in understandings of discrimination and measurement bias; multiple stakeholders' perceptions; and ....Measurement matters: analysis of potential methodological and discrimination biases in assessments of medication treatments for ADHD, and stakeholder views. This research aims to identify multiple stakeholders' views of the nature of Attention Deficit Hyperactivity Disorder and test if discrimination and survey wording result in bias when assessing the impact of medical treatments. This will result in understandings of discrimination and measurement bias; multiple stakeholders' perceptions; and better methodology in research.
Read moreRead less
Experimental and computational assessment of the mechanical, musculo-skeletal and neuromuscular contributions to rhythmic multi-joint arm movements. The human body is a complex mechanical system that is controlled by a vast neural network comprising many millions of connections. To date, realistic descriptions of the interactions between these neuro-mechanical features have proved elusive. This project seeks to develop a mathematical model that accurately describes the essential features of the ....Experimental and computational assessment of the mechanical, musculo-skeletal and neuromuscular contributions to rhythmic multi-joint arm movements. The human body is a complex mechanical system that is controlled by a vast neural network comprising many millions of connections. To date, realistic descriptions of the interactions between these neuro-mechanical features have proved elusive. This project seeks to develop a mathematical model that accurately describes the essential features of the control system for human movement, and yet is simple enough to inform the design of artificial devices to generate or assist movement. The knowledge derived should improve mechanical and neural prosthetic systems, and guide rehabilitation protocols. The work will ultimately provide a considerable benefit to the community by reducing the social cost of a range of movement disorders.Read moreRead less
An inverse control approach to resolving the neural basis of spatial and muscular dependencies in coordinated multi-limb movements. Each year 48,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will ....An inverse control approach to resolving the neural basis of spatial and muscular dependencies in coordinated multi-limb movements. Each year 48,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced quality of life and functional life-span, as well as significantly reduced costs of health care. In understanding the fundamental principles underlying the stability and adaptability of movement coordination, this research is likely to make a significant contribution to the design of programs for movement rehabilitation.Read moreRead less
Cortical Mechanisms Mediating Bilateral Interactions Between the Upper Limbs. Each year 40,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced qual ....Cortical Mechanisms Mediating Bilateral Interactions Between the Upper Limbs. Each year 40,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced quality of life and functional life-span, as well as significantly reduced costs of health care. In understanding the fundamental principles underlying the stability and adaptability of movement coordination, this research is likely to make a significant contribution to the design of programs for rehabilitation of the upper limb.Read moreRead less
The neural basis of interlimb coordination. The aims of the proposed research program are to increase our understanding the control of voluntary movement. It is expected that the outcomes of this research program will have eventual application to a number of acquired movement deficits, in particular those arising from spinal cord and brain injury. This research will also be of diagnostic value in determining the integrity of the motor pathways, in both acquired and developmental movement disorde ....The neural basis of interlimb coordination. The aims of the proposed research program are to increase our understanding the control of voluntary movement. It is expected that the outcomes of this research program will have eventual application to a number of acquired movement deficits, in particular those arising from spinal cord and brain injury. This research will also be of diagnostic value in determining the integrity of the motor pathways, in both acquired and developmental movement disorders.Read moreRead less