The Future of Australian Mineral Exports. Australia is among the world's largest exporters of steelmaking raw materials, specifically iron ore, coking coal and manganese. This project will develop an integrated econometric model of the global steel industry to forecast future trends in global steel production and the associated demand for raw materials. The results of this research will not only assist Australian mineral exporters in achieving better outcomes in annual pricing negotiations by im ....The Future of Australian Mineral Exports. Australia is among the world's largest exporters of steelmaking raw materials, specifically iron ore, coking coal and manganese. This project will develop an integrated econometric model of the global steel industry to forecast future trends in global steel production and the associated demand for raw materials. The results of this research will not only assist Australian mineral exporters in achieving better outcomes in annual pricing negotiations by improving market knowledge, but also help focus their longer term marketing strategies. The extensive global mine database to be assembled as part of the network flow component of this model will also allow Australian mineral exporters to assess their competitive position relative to foreign producers.Read moreRead less
The Cambrian Population Explosion of Arthropods in Australia: Ediacaran origins, evolution and biodiversity. This project addresses key questions on the origin and diversification of life, by investigating the evolution of the most important fossil group (arthropods) across arguably the most important event after the origin of life (the Cambrian explosion of macroscopic life). It will also excavate, promote and conserve two key geological resources of national importance, in the Flinders Ranges ....The Cambrian Population Explosion of Arthropods in Australia: Ediacaran origins, evolution and biodiversity. This project addresses key questions on the origin and diversification of life, by investigating the evolution of the most important fossil group (arthropods) across arguably the most important event after the origin of life (the Cambrian explosion of macroscopic life). It will also excavate, promote and conserve two key geological resources of national importance, in the Flinders Ranges and Kangaroo Island. Also, it will lead to increased knowledge of the palaeoecology and geology of the economically-important Adelaide geosyncline, and benefit rural SA communities through ecotourism, a rural schools education program, and public outreach.Read moreRead less
Deep Downunder: designing a deep-sea exploration and discovery capability for Australia. Exploration of the deep-sea with the modern technologies to be developed by Deep-Downunder is a first for Australia. We aim to explore and discover life at depths from 50-3000m off The Great Barrier Reef, around the seamounts of Lord Howe Island and Tasmania and in the deep canyons of WA and SA. We expect to discover new species, hope for a glimpse of giant squid at home and will answer specific questions on ....Deep Downunder: designing a deep-sea exploration and discovery capability for Australia. Exploration of the deep-sea with the modern technologies to be developed by Deep-Downunder is a first for Australia. We aim to explore and discover life at depths from 50-3000m off The Great Barrier Reef, around the seamounts of Lord Howe Island and Tasmania and in the deep canyons of WA and SA. We expect to discover new species, hope for a glimpse of giant squid at home and will answer specific questions on Australia's ocean biology, fisheries and biotechnology never before approachable. To be effective guardians of Australian waters we must learn what lies in the depths we can't see from a boat.Read moreRead less
Neurons isolated from embryonic stem cells as functional models for drug discovery. By using gene expression-based selection criteria embryonic stem cells can be driven to differentiate into specific neuronal lineages which show many of the morphological characteristics and immunocytochemical features of neurons in culture. There is, however, comparatively little evidence indicating that these stem cell-derived neurons actually behave as neurons. Our aim is to characterise and contrast four ne ....Neurons isolated from embryonic stem cells as functional models for drug discovery. By using gene expression-based selection criteria embryonic stem cells can be driven to differentiate into specific neuronal lineages which show many of the morphological characteristics and immunocytochemical features of neurons in culture. There is, however, comparatively little evidence indicating that these stem cell-derived neurons actually behave as neurons. Our aim is to characterise and contrast four neuronal cell cultures established with gene-based selection criteria. These cultures will be characterised by gene expression, immunocytochemistry, radiolabelled neurotransmitter release, electrophysiology and Ca2+ imaging studies. This study will highlight the functional effects of gene selection procedures upon stem cell-derived neurons.Read moreRead less
Regulation of large artery stiffness by endothelium-derived mediators and effects on the arterial pressure waveform. Stiffening of arteries is an important cardiovascular risk factor and increases with age, high blood pressure, high cholesterol and diabetes. Cells that line the blood vessels (endothelial cells), become damaged and this reduces the available amount of a dilator substance, nitric oxide, and increases the activity of a constrictor substance, endothelin-1. We have shown that nitric ....Regulation of large artery stiffness by endothelium-derived mediators and effects on the arterial pressure waveform. Stiffening of arteries is an important cardiovascular risk factor and increases with age, high blood pressure, high cholesterol and diabetes. Cells that line the blood vessels (endothelial cells), become damaged and this reduces the available amount of a dilator substance, nitric oxide, and increases the activity of a constrictor substance, endothelin-1. We have shown that nitric oxide regulates large artery stiffness and we believe that other endothelial mediators are also important regulators. Therefore, we aim to explore this in a series of studies. Regulation of stiffness of large arteries will improve treatment of age-related cardiovascular disease (eg isolated systolic hypertension)Read moreRead less
Value Adding to Australian Cashmere Fleece. This project will lead to major technical advance in the processing of both cashmere fibres and cashmere guard hair. Reducing the level of breakage in fine cashmere fibres will add significant premium to the price of cashmere fibres and products. In addition, the large amount of coarse guard hair removed from cashmere dehairing process will be converted into quality fine powders, which will add significant value to an otherwise 'waste' product. This pr ....Value Adding to Australian Cashmere Fleece. This project will lead to major technical advance in the processing of both cashmere fibres and cashmere guard hair. Reducing the level of breakage in fine cashmere fibres will add significant premium to the price of cashmere fibres and products. In addition, the large amount of coarse guard hair removed from cashmere dehairing process will be converted into quality fine powders, which will add significant value to an otherwise 'waste' product. This project will benefit the entire animal fibre industry, particularly the rare animal fibre industry.Read moreRead less
Nanoparticles with designed morphology for surface-coating applications. Significantly improved water-based paints, with zero volatile organic content and organic opacifiers, are highly desirable for environmental and health reasons. The science needed to produce such paints has been persistently elusive. USyd and Dulux will collaborate to achieve these paints by using Australian-developed platform technologies that allow polymer architecture to be controlled at molecular and nanoscale levels. T ....Nanoparticles with designed morphology for surface-coating applications. Significantly improved water-based paints, with zero volatile organic content and organic opacifiers, are highly desirable for environmental and health reasons. The science needed to produce such paints has been persistently elusive. USyd and Dulux will collaborate to achieve these paints by using Australian-developed platform technologies that allow polymer architecture to be controlled at molecular and nanoscale levels. This will give us the means to make structured nanoparticles with morphologies that had been regarded as unachievable, and that are the key to dispensing with harmful ingredients in paints.Read moreRead less
Particle Transport and Separation in High Aspect Ratio Inclined Channels. This project will be of benefit to the Australian coal and mineral processing industries, worth tens of billions of dollars to the Australian economy each year. The objective is to establish new options for the processing of particles as large as 50mm, and smaller than 50 microns in size, and hence significantly extend the operating size range of the Reflux Classifier. The development of new resources, especially those of ....Particle Transport and Separation in High Aspect Ratio Inclined Channels. This project will be of benefit to the Australian coal and mineral processing industries, worth tens of billions of dollars to the Australian economy each year. The objective is to establish new options for the processing of particles as large as 50mm, and smaller than 50 microns in size, and hence significantly extend the operating size range of the Reflux Classifier. The development of new resources, especially those of poorer grade, requires more effective separation technology. Success in this project will significantly benefit the end users of the technology and also contribute to Australia's Mining Services industry.Read moreRead less
Better Planning for and Managing Asymmetric Threats to Australia's Security: Applying the Field Anomaly Relaxation (FAR) Systems Thinking Approach. Despite an enviable national security condition, Australia is at risk in an information-abundant world that increasingly spawns asymmetric threats such as information terrorism. What is needed are enhanced strategic and operational structures to improve the nation's security and ensure sound futures planning. This research focuses on applying the Fie ....Better Planning for and Managing Asymmetric Threats to Australia's Security: Applying the Field Anomaly Relaxation (FAR) Systems Thinking Approach. Despite an enviable national security condition, Australia is at risk in an information-abundant world that increasingly spawns asymmetric threats such as information terrorism. What is needed are enhanced strategic and operational structures to improve the nation's security and ensure sound futures planning. This research focuses on applying the Field Anomaly Relaxation (FAR) systems thinking approach to asymmetric information warfare threats to Australia. This is a new approach previously developed by ECU researchers investigating risk and innovation in the armed forces. It will now be extended to improve professional practice and the knowledge and skill base of Australia's information defence practitioners.Read moreRead less
The potential of biosolids and flyash mixtures for soil remediation for revegetation of degraded land. Revegetation of land that has been subjected to land clearing or mining is often limited by the poor quality or lack of topsoil. It may prove possible to remediate these areas of land by incorporating a mixture of two waste products, biosolids and flyash. The aim in this project is to determine the usefulness of this method of land remediation by investigating the nutrient levels and fate of co ....The potential of biosolids and flyash mixtures for soil remediation for revegetation of degraded land. Revegetation of land that has been subjected to land clearing or mining is often limited by the poor quality or lack of topsoil. It may prove possible to remediate these areas of land by incorporating a mixture of two waste products, biosolids and flyash. The aim in this project is to determine the usefulness of this method of land remediation by investigating the nutrient levels and fate of contaminants in various mixtures of biosolids and flyash materials, in the absence and presence of soil minerals, and soil ameliorants such as fertilizers and gypsum.Read moreRead less