New Approaches to the Control of Post-Weaning Diarrhoea in Piglets. In Australia, post?weaning diarrhoea (PWD) in piglets is a major constraint to efficient and profitable production. Increasing levels of resistance to dietary antibiotics by gut pathogens such as Escherichia coli, the bacterium implicated in PWD, is a major reason for this problem. This research will identify nutritional means of controlling PWD and increasing production after weaning. This will be achieved by strategic nutritio ....New Approaches to the Control of Post-Weaning Diarrhoea in Piglets. In Australia, post?weaning diarrhoea (PWD) in piglets is a major constraint to efficient and profitable production. Increasing levels of resistance to dietary antibiotics by gut pathogens such as Escherichia coli, the bacterium implicated in PWD, is a major reason for this problem. This research will identify nutritional means of controlling PWD and increasing production after weaning. This will be achieved by strategic nutritional interventions in the pre-weaning and (or) post-weaning periods targeted at reducing bacterial pathogens in the gut. A reduction in PWD will increase the overall efficiency of pig production in Australia and reduce antibiotic use.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190101364
Funder
Australian Research Council
Funding Amount
$422,460.00
Summary
Securing future supplies of chicken-meat protein. This project aims to generate advanced knowledge in amino acid metabolism in poultry in order to reduce soybean inclusion in broiler diets. Chicken-meat is the dominant animal protein source in human diets in Australia. However, Australia chicken-meat industry will need to increase production by more than 40 per cent to meet population growth by 2050. Soybean meal is the major protein source in poultry diets but the sustainability of increased so ....Securing future supplies of chicken-meat protein. This project aims to generate advanced knowledge in amino acid metabolism in poultry in order to reduce soybean inclusion in broiler diets. Chicken-meat is the dominant animal protein source in human diets in Australia. However, Australia chicken-meat industry will need to increase production by more than 40 per cent to meet population growth by 2050. Soybean meal is the major protein source in poultry diets but the sustainability of increased soy production is problematic. The expected outcomes of this project will be an increase in our future capacity to produce affordable, healthy chicken-meat with humane animal welfare by novel dietary formulations. Chicken-meat production generates less greenhouse gases than its competitors but this project will contribute to the reduction of harmful environmental outputs and ensure food security for Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101470
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Improving poultry health and performance through microbiota manipulations. The project aims to develop methods to modulate microbiota to improve poultry health and productivity and reduce the need for antibiotics. Probiotic administration is currently the only way in agriculture to restore imbalanced intestinal microbiota. Recent research shows that intestinal microbiota resist all new-coming bacteria and remove them from the intestinal environment. The initial inoculum at the time of birth shap ....Improving poultry health and performance through microbiota manipulations. The project aims to develop methods to modulate microbiota to improve poultry health and productivity and reduce the need for antibiotics. Probiotic administration is currently the only way in agriculture to restore imbalanced intestinal microbiota. Recent research shows that intestinal microbiota resist all new-coming bacteria and remove them from the intestinal environment. The initial inoculum at the time of birth shapes the gut microbiota for life and has the strongest influence on development of the immune system. Accordingly, at-hatch administration of proven beneficial strains to poultry is likely to ensure permanent colonisation with beneficial bacteria. This process would improve both the productivity and health of poultry and other agricultural animals.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170101132
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
How social relationships improve sheep productivity. This project aims to determine how the social network structure of a flock and different individuals’ experience and leadership abilities improve a population’s well-being and productivity (wool clip and lambing rates). This project will use social network theory and collective behaviour in animals to manage sheep in Australia’s arid rangelands, which are important for the pastoral industry, but where ecological challenges reduce livestock pro ....How social relationships improve sheep productivity. This project aims to determine how the social network structure of a flock and different individuals’ experience and leadership abilities improve a population’s well-being and productivity (wool clip and lambing rates). This project will use social network theory and collective behaviour in animals to manage sheep in Australia’s arid rangelands, which are important for the pastoral industry, but where ecological challenges reduce livestock productivity. An expected outcome is management guidelines for the sheep industry to improve wool and meat production.Read moreRead less
Quantifying the effect of nutrient-gene interaction in utero in key tissues instrumental to productivity and sustainability of the beef industry. The cattle industry occupies 43 per cent of the land mass and provides 13 per cent of rural employment. Nutritional insult in utero affects postnatal reproductive and production traits in cattle and imposes epigenetic modifications. This project investigates the effect upon genes affecting appetite, ovarian development, adipogenesis, myogenesis and pos ....Quantifying the effect of nutrient-gene interaction in utero in key tissues instrumental to productivity and sustainability of the beef industry. The cattle industry occupies 43 per cent of the land mass and provides 13 per cent of rural employment. Nutritional insult in utero affects postnatal reproductive and production traits in cattle and imposes epigenetic modifications. This project investigates the effect upon genes affecting appetite, ovarian development, adipogenesis, myogenesis and post natal growth.Read moreRead less
Maximizing male fertility: the role of CRISP proteins. This project aims to investigate the function of cysteine rich secretory protein (CRISP) family members in fertility. It is expected to generate new knowledge on the role CRISP1 and 4 play in sperm competition in vivo, and thus, evolutionary processes; to define the role seminal plasma CRISPs play in fertility; and identify the mechanism underpinning their biological activities. This will be achieved using a range of innovative, state-of-the ....Maximizing male fertility: the role of CRISP proteins. This project aims to investigate the function of cysteine rich secretory protein (CRISP) family members in fertility. It is expected to generate new knowledge on the role CRISP1 and 4 play in sperm competition in vivo, and thus, evolutionary processes; to define the role seminal plasma CRISPs play in fertility; and identify the mechanism underpinning their biological activities. This will be achieved using a range of innovative, state-of-the-art approaches. Expected outcomes and benefits include an enhanced knowledge of the mechanisms underpinning fertility and infertility, enhanced collaboration and research knowhow, and an evidence base for future applied projects aimed enhancing fertility in agricultural species.Read moreRead less
Targeting TGF-beta proteins to control animal reproduction. This project aims to develop a suite of novel biologics to control fertility in female mammals. This project expects to demonstrate that targeting a single class of ovarian proteins will enhance or inhibit egg production. The expected outcomes of this project are to (1) transform the breeding of livestock animals, which should provide significant benefits to the agricultural industry, through increased herd/flock sizes, and (2) provide ....Targeting TGF-beta proteins to control animal reproduction. This project aims to develop a suite of novel biologics to control fertility in female mammals. This project expects to demonstrate that targeting a single class of ovarian proteins will enhance or inhibit egg production. The expected outcomes of this project are to (1) transform the breeding of livestock animals, which should provide significant benefits to the agricultural industry, through increased herd/flock sizes, and (2) provide a non-surgical method of contraception in companion/feral species, which should address the large unmet need for fertility control in these animals.
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Stimulation of the mammalian reproductive system by olfactory pathways. This project answers fundamental questions about mammalian reproductive biology but, because we work with the sheep model, our findings can be applied to two of Australia's biggest export industries, wool and sheepmeat. Understanding the reproductive responses of our production animals to exteroceptive factors such as socio-sexual signals, photoperiod and nutrition is an important first step towards refining the management ....Stimulation of the mammalian reproductive system by olfactory pathways. This project answers fundamental questions about mammalian reproductive biology but, because we work with the sheep model, our findings can be applied to two of Australia's biggest export industries, wool and sheepmeat. Understanding the reproductive responses of our production animals to exteroceptive factors such as socio-sexual signals, photoperiod and nutrition is an important first step towards refining the management of breeding programs. It has been argued that this approach will also minimise, and perhaps even remove the need for, exogenous hormones and drugs for controlling the reproductive process.Read moreRead less
Development of cloning technology for the Australian Pig Industry. Cloning has the potential to be the most efficient of the reproductive technologies developed for increasing genetic improvement in livestock. Currently up to 5% of cloned embryos develop to term in the pig. This is higher than that reported for cattle and sheep. Moreover the use of this technology in the pig does not appear not to result in the same sorts of problems and losses seen around the time of birth in these species ....Development of cloning technology for the Australian Pig Industry. Cloning has the potential to be the most efficient of the reproductive technologies developed for increasing genetic improvement in livestock. Currently up to 5% of cloned embryos develop to term in the pig. This is higher than that reported for cattle and sheep. Moreover the use of this technology in the pig does not appear not to result in the same sorts of problems and losses seen around the time of birth in these species i.e. the majority of cloned pigs appear normal and are healthy at birth. However before cloning can be used commercially, current efficiencies need to be increased approx two fold for this to be economically viable. The aim of the present study is to improve the efficiency of our current cloning protocol and develop associated technologies such as embryo freezing to facilitate commercialisation. This will ensure that the Australian Pig Industry remains competitive at a pivotal time in its development.Read moreRead less
Relationships between insulin resistance, diet and obesity in ponies and horses. There are an estimated 1.2 million horses in Australia, and the horse industry is estimated to contribute over $6.3 billion to the economy. Laminitis is a significant health and welfare problem in Australia, as it is worldwide, causing pain and lameness, loss of use, and sometimes necessitating euthanasia. Laminitis is one of the most common reasons for horse owners to seek veterinary attention, and diet and obesity ....Relationships between insulin resistance, diet and obesity in ponies and horses. There are an estimated 1.2 million horses in Australia, and the horse industry is estimated to contribute over $6.3 billion to the economy. Laminitis is a significant health and welfare problem in Australia, as it is worldwide, causing pain and lameness, loss of use, and sometimes necessitating euthanasia. Laminitis is one of the most common reasons for horse owners to seek veterinary attention, and diet and obesity increasingly predispose to this condition. Since treatment of laminitis is difficult, prevention is crucial. The outcomes from this project will include the provision of more specific advice on dietary and exercise management to vets and horse owners to reduce the incidence and impact of laminitis on the horse industry.Read moreRead less