New fermentation and purification production technologies for menaquinone-7 for promoting bone and cardiovascular health. We will develop a significantly more cost-efficient and environmentally friendly process for the production of vitamin K (menaquinone-7, or MK7) to manufacture food supplements for humans and animals. MK7 will increase bone regeneration and minimise the risk of cardiovascular disease. It has the potential to reduce the costs of these conditions for the community, and to incre ....New fermentation and purification production technologies for menaquinone-7 for promoting bone and cardiovascular health. We will develop a significantly more cost-efficient and environmentally friendly process for the production of vitamin K (menaquinone-7, or MK7) to manufacture food supplements for humans and animals. MK7 will increase bone regeneration and minimise the risk of cardiovascular disease. It has the potential to reduce the costs of these conditions for the community, and to increase the quality of life for Australia's ageing population. Orthopaedic diseases are also a major veterinary issue, and our advance should make MK7 a more widely used available supplementary food for animals such as horses and dogs. Read moreRead less
Cellular Responses to Adversity: Oxidative Stress and Protection Against Oxidative Damage. A deficiency in the protein haem oxygenase-1 causes severe biological consequences in animals and humans. These include decreased reproduction, retarded development, the inability of the body to handle iron, chronic inflammation and increased susceptibility to age-associated diseases. This study will determine how a deficiency of the protein alters cells at the level of genes, proteins and protein function ....Cellular Responses to Adversity: Oxidative Stress and Protection Against Oxidative Damage. A deficiency in the protein haem oxygenase-1 causes severe biological consequences in animals and humans. These include decreased reproduction, retarded development, the inability of the body to handle iron, chronic inflammation and increased susceptibility to age-associated diseases. This study will determine how a deficiency of the protein alters cells at the level of genes, proteins and protein functions. By doing so, the project will illuminate how haem oxygenase-1 alters cell functions in a beneficial way. This information will eventually assist in preventing the serious disorders associated with deficiency of haem oxygenase-1. It will also provide the basis for novel treatments to slow down age-associated diseases.Read moreRead less
The use of social marketing strategies and adult education principles to improve asthma self management in older people. Asthma is estimated to affect up to 10 per cent of people aged 65+ some of whom experience the condition for the first time later in life. Mortality rates from asthma in Australia are highest in the older population and statistics show that older people are most likely to be admitted to hospital following attendance at an Emergency Department for asthma. Older people lack aw ....The use of social marketing strategies and adult education principles to improve asthma self management in older people. Asthma is estimated to affect up to 10 per cent of people aged 65+ some of whom experience the condition for the first time later in life. Mortality rates from asthma in Australia are highest in the older population and statistics show that older people are most likely to be admitted to hospital following attendance at an Emergency Department for asthma. Older people lack awareness about asthma, often manage it poorly, and their health related quality of life is impacted by asthma. There is disparity in asthma information, management and service provision targeted specifically to the needs of the elderly. This project will provide much-needed evidence on the effectiveness of carefully researched and targeted programs for older asthmatics.Read moreRead less
Access to mobile communications for older people with impairments. This research will determine the potential to use mobile communications to enable older people with impairments to remain active members of the community. it will test the capacity for mobiles to enable:
* older people with impairments to maintain social communication links and summon assistance; and
* caregivers to maintain contact with the older person during the day.
Providing these capabilities has the potential to improve ....Access to mobile communications for older people with impairments. This research will determine the potential to use mobile communications to enable older people with impairments to remain active members of the community. it will test the capacity for mobiles to enable:
* older people with impairments to maintain social communication links and summon assistance; and
* caregivers to maintain contact with the older person during the day.
Providing these capabilities has the potential to improve the wellbeing and confidence of older people with impairments and their caregivers and to reduce negative outcomes due to falls or other medical problems by enabling older people to summon assistance easily.Read moreRead less
Economic and Social Benefits of treating and preventing influenza in Aged Care Facilities. Influenza is a deadly issue for the elderly, their carers and the community. It reduces quality of life and productivity through hospitalisation and work absenteeism. By preventing influenza using an antiviral drug for residents and staff in aged care facilities there should be considerable economic and social benefits. This controlled scientific experiment will determine how much disease and death can be ....Economic and Social Benefits of treating and preventing influenza in Aged Care Facilities. Influenza is a deadly issue for the elderly, their carers and the community. It reduces quality of life and productivity through hospitalisation and work absenteeism. By preventing influenza using an antiviral drug for residents and staff in aged care facilities there should be considerable economic and social benefits. This controlled scientific experiment will determine how much disease and death can be averted and provide real data that is critical to planning for an influenza pandemic. It will direct where emphasis should be placed between the control measures of infection control (eg hand-washing, masks), vaccination and use of antiviral drugs. Annual outbreaks will be curtailed.Read moreRead less