A multidimensional model of social cognitive ageing. This project aims to develop and test a model of how normal adult ageing affects the critical ability to perceive, interpret and process social information. By using an innovative approach that integrates laboratory-based assessments with measures of real-life social behaviour, this project expects to generate novel insights into how ageing affects a range of important social cognitive skills, as well as when and why any age-related difficulti ....A multidimensional model of social cognitive ageing. This project aims to develop and test a model of how normal adult ageing affects the critical ability to perceive, interpret and process social information. By using an innovative approach that integrates laboratory-based assessments with measures of real-life social behaviour, this project expects to generate novel insights into how ageing affects a range of important social cognitive skills, as well as when and why any age-related difficulties emerge. Expected outcomes include a better understanding of the factors that drive resilience and risk for social cognitive difficulties in late adulthood, with direct implications for promoting social engagement and preventing social detachment in Australia’s growing older adult community.Read moreRead less
Harnessing non-invasive brain stimulation to improve language function in healthy and pathological ageing. This project will examine how the ability of the ageing brain to process language can be improved by non-invasive brain stimulation. The findings have the potential to reveal new ways to treat language impairments in ageing-associated brain injury and disease.
Novel pharmacological agents to target stroke-induced brain injury. There is a looming stroke epidemic in Australia. 72% of Australian stroke sufferers are over the age of 65 and whereas in 1997 only 12% of Australians were in that age group, by 2030 that number will have increased to 23%. There is an urgent need for novel therapies. This project will aid the development of a novel anti-stroke therapy.
Molecules and mechanisms regulating axonal degeneration and regeneration in Caenorhabditis elegans neurons. Understanding the molecular mechanisms underlying nerve degeneration and regeneration is essential to tackle and provide treatment for neurodegenerative diseases and injury of the nervous system. This project aims to discover, using a genetic approach and a simple animal model system, the molecules regulating these crucial biological processes.
Metals in biocatalysis. Metals and enzymes are essential for the chemistry of life. This project will aim to garner the potential of metal-dependent enzymes to develop new drugs against osteoporosis, combat the spread of antibiotics resistance and optimise some of these enzymes to detoxify pesticide-polluted environments, thus contributing to global health and food security.
What about the children? A study of the intergenerational consequences of paternal incarceration. Parental incarceration may have a profound and detrimental effect on children, heightening risk of offending and extreme disadvantage. The proportion of children affected is certain to increase as prison populations continue to grow. This research will identify policies and prevention strategies that will interrupt the cycle of disadvantage for children of prisoners and prevent social exclusion. Sig ....What about the children? A study of the intergenerational consequences of paternal incarceration. Parental incarceration may have a profound and detrimental effect on children, heightening risk of offending and extreme disadvantage. The proportion of children affected is certain to increase as prison populations continue to grow. This research will identify policies and prevention strategies that will interrupt the cycle of disadvantage for children of prisoners and prevent social exclusion. Significant cost-savings and prevention of victimisation could result from effectively targeting this high-risk population, reducing risk of offending and increasing the young person's ability to contribute meaningfully to society. Appropriately timed programs can deliver a range of long-term benefits for children, families and communities.Read moreRead less
Trajectories and turning points for women's reproductive health. This project will take a whole life perspective to investigate women’s reproductive health. It uses data from more than 150,000 women in 10 cohort studies across six nations. Findings will advance our understanding of reproductive health and will support a more tailored approach to women’s health policy and strategies for healthy ageing.
Excessive sitting and population health: strengthening the science and the relevance to policy and practice. The majority of Australian adults spend most of their waking hours sitting; this increases the likelihood of developing diseases of inactivity, including diabetes, heart disease and some cancers. New research will investigate what factors encourage excessive sitting and what the health benefits are for people who deliberately do less sitting.
A longitudinal study into the development of personal vulnerabilities and well-being in adolescence. This longitudinal study examines the temperament and environmental factors that promote character strengths in adolescents. Character strengths such as empathy and emotion-management skills are potentially teachable and help prevent an adolescent from experiencing difficulties in social, emotional and academic adjustment.
Defining the molecular mechanisms of intracellular protein trafficking. Intracellular trafficking of proteins is critical for normal cell function and defects can lead to many different human diseases. Outcomes from this project will lead to insights into how trafficking is regulated at the atomic level and will help place Australia at the forefront of international efforts to understand this essential process.