Combating Escalating Harms Associated With Pharmaceutical Opioid Use
Funder
National Health and Medical Research Council
Funding Amount
$925,767.00
Summary
Increases in opioid use have been accompanied by increased opioid harms. But there is a lack of population-level evidence about drivers of long-term prescribed opioid use, dependence, overdose and other harms. Using linked data, we will fill these gaps using a cohort of all people in NSW prescribed opioids since 2002, linked to datasets containing information on health, social and health service utilisation, that will permit a comprehensive assessment of the risks of all prescribed opioids.
Post-market Surveillance Of Medicine-related Adverse Events
Funder
National Health and Medical Research Council
Funding Amount
$99,248.00
Summary
Observational studies using administrative data are an important complement to spontaneous reporting systems for detecting medicine-related adverse events after they go to market, as they reflect real-world use of medicines; yet, they require rigorous methodological approaches to avoid bias. This project will review the existing methodologies for detecting adverse events in administrative data and apply them to Australian data.
Temporal Trends In The Incidence, Site And Survival Of Metastatic Breast Cancer In Australia
Funder
National Health and Medical Research Council
Funding Amount
$190,494.00
Summary
There have been major advances in breast cancer treatment over the last decade. This project will use information collected from the NSW cancer registry and hospitals to report on changes in the type and risk of breast cancer spread and survival for women with a new diagnosis of breast cancer before and after new treatments introduced since 2005. This information is essential for doctors to provide women with up-to-date information; and for planning appropriate health services and research.
Using Big Data To Reduce Inappropriate Medication Use
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Potentially inappropriate medication use both increases patient harm and wastes considerable health resources. However methods for measuring patterns of use are not well developed nor utilised in policy. This research will measure the scope, variation and burden of potentially inappropriate medication use in Australia. My unique combination of biostatistical, data and policy expertise will enable this research to create new actionable tools for evaluating the Australian healthcare system.
Improving The Mental Health Outcomes Of People With Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$1,189,979.00
Summary
Australians with intellectual disability (ID) have very high rates of mental illness but experience very poor access to mental health services. Our research will develop a sound evidence base on the profile of mental ill health, service use, pathways to care and mental health policy for people with intellectual disability. Together with consumers and support persons we will examine ways to improve mental health services for people with intellectual disability.
Seeding Success: Identifying Factors That Contribute To Positive Early Childhood Health And Development In Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$692,845.00
Summary
This study will identify the key drivers of positive early childhood health and development in Aboriginal children, and the features of local communities and early childhood service provision that make a tangible difference, using a large population-based cohort of children in NSW. We will apply novel methods for using linked population data that can be used to inform program planning and evaluation nationally, and will advance theory, research and practice to "seed success" for Aboriginal child ....This study will identify the key drivers of positive early childhood health and development in Aboriginal children, and the features of local communities and early childhood service provision that make a tangible difference, using a large population-based cohort of children in NSW. We will apply novel methods for using linked population data that can be used to inform program planning and evaluation nationally, and will advance theory, research and practice to "seed success" for Aboriginal children.Read moreRead less
Centre Of Research Excellence In Medicines And Ageing
Funder
National Health and Medical Research Council
Funding Amount
$2,601,415.00
Summary
Medicines have an important place in health and are commonly used for long periods, sometimes life-long. Using medicines wisely requires a careful balance between benefits and harmful effects. Currently, there is limited information to guide medicines use over a lifetime. Using large linked datasets, the CRE in Medicines and Ageing will generate much needed evidence about real world medicines use to support clinical and pharmaceutical policy decisions.
ManagemenT Of ChronIc CardioMetabolic DiseasE And Treatment DiScontinuity In Adult ADHD PAtieNts (TIMESPAN)
Funder
National Health and Medical Research Council
Funding Amount
$499,613.00
Summary
The aim of TIMESPAN is to improve the management of patients with Attention Deficit Hyperactivity Disorders (ADHD) and co-occurring cardiometabolic disease (i.e. obesity, type-2 diabetes, and cardiovascular disease). Inadequate treatment of these common conditions can lead to premature death and substantial societal costs. We will use linked electronic health records and novel research methods to improve clinical outcomes and quality of life of adults with ADHD and cardiometabolic disease.
Achieving Better Mental Health For Maltreated Children: Translating Population Data Into Policy
Funder
National Health and Medical Research Council
Funding Amount
$522,706.00
Summary
This project uses linked population data to determine (a) the earliest indicators of risk of harm, and (b) mental health outcomes and health-care costs associated with children receiving child protection services, in partnership with the NSW department of Family and Community Services. The findings will ensure timely and effective responses to the most vulnerable children to mitigate adverse mental health and other outcomes associated with early life adversity.
Developmental Schizotypy In The General Population: Early Risk Factors And Predictive Utility.
Funder
National Health and Medical Research Council
Funding Amount
$830,952.00
Summary
This study will determine early childhood risk factors for psychosis-proneness in children aged 11 years, and emerging signs and symptoms of mental health disorders of these children, using population data from the NSW Child Development Study. Determining risk for psychosis as early as possible in the life course will enable the provision of preventative interventions to children at critical points in development.