Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tib ....Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tibial defects. Furthermore, it will establish Australia's prominence in the tissue engineering field, training the next generation of young scientists and engineers. This technology will be of interest to numerous research groups and companies worldwide and will foster international collaboration, placing Australia at the forefront of this emerging field.Read moreRead less
Model-based estimation methods for improved classification of electroencephalographic data: application to monitoring depth of anaesthesia. This project will use advanced computing methods applied to electrical brain wave recordings to track how the brain changes as a person undergoes general anaesthesia during surgery. This will lead to better anaesthesia monitoring devices and reduce the chances of people experiencing pain during surgery or IQ deficits after the anaesthesia.
Characterization, modelling and control for robotic thermal ablation. This project aims to study the fundamental issues in robotic-assisted minimally invasive thermal ablation, an important therapy for patients with cancer. It aims to establish advanced characterisation and modelling methodologies for thermomechanical behaviours of soft tissues, together with automatic planning and precise manipulation control techniques for robotic thermal ablation therapies. The project will establish new know ....Characterization, modelling and control for robotic thermal ablation. This project aims to study the fundamental issues in robotic-assisted minimally invasive thermal ablation, an important therapy for patients with cancer. It aims to establish advanced characterisation and modelling methodologies for thermomechanical behaviours of soft tissues, together with automatic planning and precise manipulation control techniques for robotic thermal ablation therapies. The project will establish new knowledge and instrumentation for robotic-assisted thermal ablation and minimally invasive surgery. The outcomes of this project will produce important benefits to medicine, healthcare and medical technology industry, and further consolidate Australia’s position in innovative technologies and research and development of advanced healthcare systems and instruments.Read moreRead less
Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
Use of an animal model to understand mechanisms underlying reductions in body weight associated with use of the laparoscopic adjustable gastric band. At least one in ten Australians is classified as morbidly obese and as such are eligible for bariatric surgery. Those undergoing the surgery will achieve an average excess weight loss of up to 60 per cent, they will have reduced or eliminated diabetes and will appreciably improve their prospects of survival. These experiments aimed at understandin ....Use of an animal model to understand mechanisms underlying reductions in body weight associated with use of the laparoscopic adjustable gastric band. At least one in ten Australians is classified as morbidly obese and as such are eligible for bariatric surgery. Those undergoing the surgery will achieve an average excess weight loss of up to 60 per cent, they will have reduced or eliminated diabetes and will appreciably improve their prospects of survival. These experiments aimed at understanding the mechanisms underpinning this success have the potential to further improve surgical approaches and outcomes and provide insights that will better enable weight loss therapies for all overweight and obese Australians.Read moreRead less